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Coronary Artery Disease: HELP
Articles by Ismail Dogu Kilic
Based on 13 articles published since 2008
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Between 2008 and 2019, Ismail Dogu Kilic wrote the following 13 articles about Coronary Artery Disease.
 
+ Citations + Abstracts
1 Review Absorb bioresorbable vascular scaffold: What have we learned after 5 years of clinical experience? 2015

Caiazzo, Gianluca / Kilic, Ismail Dogu / Fabris, Enrico / Serdoz, Roberta / Mattesini, Alessio / Foin, Nicolas / De Rosa, Salvatore / Indolfi, Ciro / Di Mario, Carlo. ·Division of Cardiology, Department of Medical and Surgical Sciences, "Magna Graecia" University, Catanzaro, Italy; Cardiovascular National Institute of Health Research Biomedical Research Unit, Royal Brompton & Harefield NHS Foundation Trust, London, United Kingdom. · Cardiovascular National Institute of Health Research Biomedical Research Unit, Royal Brompton & Harefield NHS Foundation Trust, London, United Kingdom. · Cardiovascular National Institute of Health Research Biomedical Research Unit, Royal Brompton & Harefield NHS Foundation Trust, London, United Kingdom; Cardiovascular Department, "Ospedali Riuniti" & University of Trieste, Trieste, Italy. · Department of Heart and Vessels, AOUC Careggi, Florence, Italy. · National Heart Centre Singapore, Singapore. · Division of Cardiology, Department of Medical and Surgical Sciences, "Magna Graecia" University, Catanzaro, Italy. · Cardiovascular National Institute of Health Research Biomedical Research Unit, Royal Brompton & Harefield NHS Foundation Trust, London, United Kingdom. Electronic address: c.dimario@rbht.nhs.uk. ·Int J Cardiol · Pubmed #26298354.

ABSTRACT: Bioresorbable scaffolds have the potential to introduce a paradigm shift in interventional cardiology, a true anatomical and functional "vascular restoration" instead of an artificial stiff tube encased by persistent metallic foreign body. Early clinical studies using the first commercially available drug-eluting bioresorbable vascular scaffold (BVS) reported very promising safety and efficacy outcomes, comparable to best-in-class second-generation drug-eluting metal stent. To date, more than 60,000 Absorb BVSs have been implanted with only the interim analysis of one randomized trial (ABSORB II RCT) available. Recent registries have challenged the initial claim that BVS is immune from Scaffold Thrombosis (ST). However, suboptimal device expansion and insufficient intracoronary imaging guidance can explain higher than expected ST, especially in complex lesions. The aim of this review article is to critically evaluate the results of the available Absorb BVS studies and discuss the lessons learned to optimize lesion selection and implantation technique of such devices.

2 Article How should I treat an iatrogenic type IIA DeBakey-Stanford aortic dissection during a percutaneous right coronary artery intervention? 2017

Stoicescu, Claudiu / Vinereanu, Dragos / Kilic, Ismail Dogu / Nasifov, Muharrem / Goktekin, Omer / Sawaya, Fadi / Millan-Iturbe, Oscar / Søndergaard, Lars. ·University of Medicine and Pharmacy Carol Davila, Bucharest, Romania. ·EuroIntervention · Pubmed #29033388.

ABSTRACT: -- No abstract --

3 Article Turkey: coronary and structural heart interventions from 2010 to 2015. 2017

Kilic, Ismail Dogu / Karacop, Erdem / Akdemir, Ramazan / Goktekin, Omer. ·Department of Cardiology, Pamukkale University Hospitals, Denizli, Turkey. ·EuroIntervention · Pubmed #28504237.

ABSTRACT: Growing populations and ageing demographics lead to an increased burden of ischaemic heart disease and related cardiovascular interventions, resulting in pressure on healthcare systems. Although the healthcare system in Turkey has undergone comprehensive remodelling over the last decade, there are many challenges to overcome, including better reimbursement for cardiovascular interventions, standardisation of interventional cardiology services and research-related activities. In this manuscript, we present an overview of coronary and structural heart interventions in Turkey, as well as providing information on current reimbursement policies and the healthcare system.

4 Article Optical coherence tomography guidance for percutaneous coronary intervention with bioresorbable scaffolds. 2016

Caiazzo, Gianluca / Longo, Giovanni / Giavarini, Alessandra / Kilic, Ismail Dogu / Fabris, Enrico / Serdoz, Roberta / Mattesini, Alessio / Foin, Nicolas / Secco, Gioel Gabrio / De Rosa, Salvatore / Indolfi, Ciro / Di Mario, Carlo. ·Division of Cardiology, Department of Medical and Surgical Sciences, "Magna Græcia" University, Catanzaro, Italy; National Institute of Health Research Cardiovascular Biomedical Research Unit, Royal Brompton & Harefield NHS Foundation Trust, London, United Kingdom. · National Institute of Health Research Cardiovascular Biomedical Research Unit, Royal Brompton & Harefield NHS Foundation Trust, London, United Kingdom. · Pamukkale University School of Medicine, Cardiology, Denizli, Turkey. · National Institute of Health Research Cardiovascular Biomedical Research Unit, Royal Brompton & Harefield NHS Foundation Trust, London, United Kingdom; Cardiovascular Department, "Ospedali Riuniti" & University of Trieste, Trieste, Italy. · National Heart Centre Singapore, Singapore. · Division of Cardiology, Department of Medical and Surgical Sciences, "Magna Græcia" University, Catanzaro, Italy. · National Institute of Health Research Cardiovascular Biomedical Research Unit, Royal Brompton & Harefield NHS Foundation Trust, London, United Kingdom. Electronic address: c.dimario@rbht.nhs.uk. ·Int J Cardiol · Pubmed #27404705.

ABSTRACT: BACKGROUND: The effect of optical coherence tomography (OCT) guidance on the implantation strategy during all phases of percutaneous coronary intervention (PCI) with bioresorbable vascular scaffolds (BVSs) in a real-world scenario has been poorly investigated. METHODS: Consecutive patients undergoing BVS implantation at our institution were included in this registry. Frequency-domain OCT pullbacks were performed at the operator's discretion during all phases of BVS implantation procedures to optimize preparation of lesions, confirm BVS size, and optimize expansion and apposition of scaffolds. RESULTS: Between September 2012 and July 2015, 203 BVSs were implanted in 101 consecutive patients at our institution (2.01 BVSs/patient). In 66 patients, the procedure was performed under OCT guidance. In the OCT subgroup, 66 (77.6%) of the 85 treated lesions were complex (B2/C AHA/ACC type). Overall, 147 OCT pullbacks were performed and 72/147 (49.0%) pullbacks indicated the need for changing strategy. After angiography-only-guided optimisation of BVS in 27 (31.8%) lesions, an OCT examination prompted performance of a second post-expansion. This resulted in an increase in the minimal scaffold area (5.5 to 6.3mm(2), p=0.004) and a decrease in the incomplete scaffold apposition area (1.1 to 0.6mm(2), p=0.082), with no new stent fractures. When the population was divided according to the time of BVS implantation, an initial learning adaptation became evident, with the number of OCT-guided changes in strategy significantly decreasing between the initial and final time periods (p=0.017). CONCLUSIONS: OCT guidance for BVS implantation significantly affects the procedural strategy, with favourable effects on acute results and the learning curve.

5 Article Bioresorbable vascular scaffold restenosis: intravascular imaging evaluation. 2016

Fabris, Enrico / Kilic, Ismail Dogu / Caiazzo, Gianluca / Serdoz, Roberta / Foin, Nicolas / Sinagra, Gianfranco / Di Mario, Carlo. ·aThe NIHR Cardiovascular BRU, Royal Brompton Hospital & NHLI Imperial College, London, UK bCardiovascular Department, Ospedali Riuniti and University of Trieste, Trieste, Italy cDepartment of Cardiology, Pamukkale University, Denizli, Turkey dNational Heart Centre, Singapore, Singapore. ·J Cardiovasc Med (Hagerstown) · Pubmed #26599682.

ABSTRACT: : The mechanism of restenosis in bioresorbable vascular scaffold (BVS) may be different from that of metallic stents and it is still poorly investigated. Intravascular imaging techniques are useful tools for corroborating or excluding possible mechanisms of intra-scaffold restenosis. In these novel devices intravascular imaging should be systematically used for a better comprehension of the in-scaffold restenosis mechanism.

6 Article Indications and immediate and long-term results of a novel pericardium covered stent graft: Consecutive 5 year single center experience. 2016

Secco, Gioel Gabrio / Serdoz, Roberta / Kilic, Ismail Dogu / Caiazzo, Gianluca / Mattesini, Alessio / Parisi, Rosario / De Luca, Giuseppe / Pistis, Gianfranco / Marino, Paolo Nicola / Di Mario, Carlo. ·NIHR Biomedical Research Unit, Royal Brompton & Harefield NHS Foundation Trust, London, United Kingdom. · Interventional Cardiology, "Antonio E Biagio E Cesare Arrigo" Hospital, Alessandria, Italy. · Department of Cardiology, Pamukkale University, Denizli, Turkey. · Department of Cardiology, University of Eastern Piedmont, Novara, Italy. ·Catheter Cardiovasc Interv · Pubmed #26541909.

ABSTRACT: BACKGROUND: The use of covered stent grafts during percutaneous coronary intervention (PCI) is a life saving solution to seal acute iatrogenic vessel rupture. However, the presence of an impenetrable mechanical barrier is also appealing during treatment of friable coronary plaques but the synthetic PTFE-membrane that might trigger excessive neointimal proliferation has limited its elective-use. Pericardium tissue may offer an appealing "natural" alternative. Aim of our study is to report the consecutive 5-year single center experience with the use of pericardium-covered stents (PCS) (ITGI-Medical, Israel) in a variety of emergency and elective applications. METHODS: Nineteen consecutive patients undergoing implantation of PCS at the Royal Brompton in the last 5-years. Reasons for PCS implantation included treatment of degenerated vein grafts, large coronary aneurysms, and acute iatrogenic vessel rupture. RESULTS: Angiographic success, defined as the ability of the device to be deployed in the indexed lesion with no contrast extravasation with residual angiographic stenosis <30% and a final thrombolysis in myocardial infarction (TIMI)-3 flow was achieved in all cases. Procedural success, defined as the achievement of angiographic success without any major adverse cardiovascular event (MACE) was achieved in 94.7% of patients. In-stent restenosis (ISR) was observed in 26.3% and all patients underwent successful target vessel revascularization with DES (mean time to restenosis 9.0 ± 4.0 months). At a mean follow-up of 32.5 ± 23.3 months no acute or late stent thrombosis was observed. CONCLUSION: PCSs were effective in the treatment of friable embolization-prone coronary plaques, sealing of acute iatrogenic vessel rupture and exclusion of large aneurysms with no thrombosis but high target lesion revascularization.

7 Article Is high pressure postdilation safe in bioresorbable vascular scaffolds? Optical coherence tomography observations after noncompliant balloons inflated at more than 24 atmospheres. 2016

Fabris, Enrico / Caiazzo, Gianluca / Kilic, Ismail Dogu / Serdoz, Roberta / Secco, Gioel Gabrio / Sinagra, Gianfranco / Lee, Renick / Foin, Nicolas / Di Mario, Carlo. ·NIHR Biomedical Research Unit, Royal Brompton and Harefield NHS Foundation Trust, London, United Kingdom. · Cardiovascular Department, Ospedali Riuniti and University of Trieste, Trieste, Italy. · Department of Cardiology, Pamukkale University, Denizli, Turkey. · Department of Clinical and Experimental Medicine, University of Eastern Piedmont, Novara, Italy. · National Heart Centre Singapore, Singapore. ·Catheter Cardiovasc Interv · Pubmed #26370357.

ABSTRACT: OBJECTIVES: Optical coherence tomography (OCT) was used to investigate integrity and expansion of bioresorbable drug-eluting scaffolds (BVS) after high-pressure postdilation (HPPD). BACKGROUND: Because of concerns about the risk of BVS damage, postdilation was not recommended and applied in the existing randomized studies and most registries. Recent real world data suggest incomplete BVS expansion cause higher rates of thrombosis. In vivo confirmation of the safety of high pressure postdilation is of paramount importance. METHODS: Data from final OCT examination of consecutive implanted BVS, postdilated with noncompliant (NC) balloons at pressure ≥24 atm were analyzed. The following stent performance indices were assessed with OCT: mean and minimal lumen and scaffold area, residual area stenosis (RAS), incomplete strut apposition (ISA), tissue prolapse, eccentricity index (EI), symmetry index (SI), strut fractures, and edge dissections. RESULT: Twenty-two BVS postdilated at high pressure were analyzed. The average maximal postdilation balloon inflation (maxPD) was 28 ± 3 atm. High pressure OPN NC Balloon (SIS Medical AG, Winterthur Switzerland) was used in 41% of postdilations with a maximal PD of 30 ± 4.7 atm. Final mean and minimal lumen area were 6.8 ± 1.4 and 5.5 ± 1.4 mm(2) , respectively. OCT showed low percentage of RAS (16 ± 9.6%), and low percentage of ISA (1.8 ± 2.4%). Mean EI was 0.86 ± 0.02 and SI 0.35 ± 0.14. OCT analysis showed one edge dissection and no scaffold fractures. CONCLUSIONS: BVS deployment optimization using HPPD does not cause BVS disruption and is associated with a good BVS expansion, low rate of strut malapposition and edge dissections.

8 Article Three-dimensional optical coherence tomography reconstruction of a long coronary artery dissection: advantages over intravascular ultrasound imaging. 2016

Caiazzo, Gianluca / Kilic, Ismail Dogu / Foin, Nicolas / Fabris, Enrico / Serdoz, Roberta / Indolfi, Ciro / Di Mario, Carlo. ·aDivision of Cardiology, Department of Medical and Surgical Sciences, 'Magna Graecia' University, Catanzaro, Italy bCardiovascular National Institute of Health Research, Biomedical Research Unit, Royal Brompton & Harefield NHS Foundation Trust, London, UK cNational Heart Centre, Singapore, Singapore. ·J Cardiovasc Med (Hagerstown) · Pubmed #26164450.

ABSTRACT: -- No abstract --

9 Article Stent deformation at the edge of a high pressure balloon. 2015

Kilic, Ismail Dogu / Foin, Nicolas / Konstantinidis, Nikolaos / Serdoz, Roberta / Caiazzo, Gianluca / Di Mario, Carlo. ·The NIHR Cardiovascular BRU, Royal Brompton Hospital & NHLI Imperial College, London, UK. · National Heart Centre, Singapore. · The NIHR Cardiovascular BRU, Royal Brompton Hospital & NHLI Imperial College, London, UK. Electronic address: c.dimario@rbht.nhs.uk. ·Cardiovasc Revasc Med · Pubmed #25819072.

ABSTRACT: Focal ultrashort balloons are essential tools for lesion preparation and final stent expansion. However, they may cause a major distortion of the adjacent segments. Here we report a case with a stent deformation emphasizing the importance of utilizing intravascular imaging techniques for optimal interventions.

10 Article Atrial tachycardia treated by coil embolization of a giant coronary artery fistula. 2014

Alihanoglu, Yusuf Izzettin / Uludag, Burcu / Kilic, Ismail Dogu / Yildiz, Bekir Serhat / Kocyigit, Ali / Evrengul, Harun. ·Department of Cardiology, Pamukkale University Medical Faculty, Denizli, Turkey. Electronic address: aliizyu@mynet.com. · Department of Cardiology, Pamukkale University Medical Faculty, Denizli, Turkey. · Department of Radiology, Pamukkale University Medical Faculty, Denizli, Turkey. ·Rev Port Cardiol · Pubmed #25442001.

ABSTRACT: Coronary artery fistulas are the second most frequently seen coronary anomaly following abnormalities of coronary artery origin and distribution. A coronary fistula is defined as a direct communication between a coronary artery and any cardiac chamber or vessel. Treatment options include percutaneous embolization and surgical intervention. Herein, we present a case of a giant coronary artery fistula and right atrial tachycardia that was induced during a diagnostic electrophysiologic study but was not inducible after the successful treatment of the fistula. This is the first case indicating this association.

11 Article Atherosclerotic changes in coronary aneurysms post-Kawasaki disease: in vivo demonstration with near-infrared spectroscopy and intravascular ultrasound. 2014

Kilic, Ismail Dogu / Di Mario, Carlo. ·NIHR Cardiovascular Biomedical Research Unit, Royal Brompton Hospital, NHLI Imperial College, Sydney Street, London SW3 6NP, UK. · NIHR Cardiovascular Biomedical Research Unit, Royal Brompton Hospital, NHLI Imperial College, Sydney Street, London SW3 6NP, UK c.dimario@rbht.nhs.uk. ·Eur Heart J · Pubmed #24917646.

ABSTRACT: -- No abstract --

12 Minor Retrieval of fractured guide wire with balloon support in intermediate coronary artery: A rare complication and management. 2016

Yildiz, Bekir Serhat / Kilic, Ismail Dogu / Alihanoglu, Yusuf Izzettin / Evrengul, Harun. ·Pamukkale University, Medical Faculty, Department of Cardiology, Denizli, Turkey. Electronic address: bserhatyildiz@yahoo.com. · Pamukkale University, Medical Faculty, Department of Cardiology, Denizli, Turkey. · Professor, Pamukkale University, Medical Faculty, Department of Cardiology, Denizli, Turkey. ·Indian Heart J · Pubmed #27316491.

ABSTRACT: -- No abstract --

13 Minor Three-vessel coronary artery disease evaluation by multimodality imaging with near-infrared spectroscopy (NIRS) plus intravascular ultrasound (IVUS) and optical coherence tomography (OCT). 2015

Fabris, Enrico / Kilic, Ismail Dogu / Caiazzo, Gianluca / Serdoz, Roberta / Sinagra, Gianfranco / Di Mario, Carlo. ·The NIHR Cardiovascular BRU, Royal Brompton Hospital, London, UK; NHLI Imperial College, London, UK; Cardiovascular Department, Ospedali Riuniti and University of Trieste, Trieste, Italy. · The NIHR Cardiovascular BRU, Royal Brompton Hospital, London, UK; NHLI Imperial College, London, UK; Department of Cardiology, Pamukkale University, Denizli, Turkey. · The NIHR Cardiovascular BRU, Royal Brompton Hospital, London, UK; NHLI Imperial College, London, UK. · Cardiovascular Department, Ospedali Riuniti and University of Trieste, Trieste, Italy. · The NIHR Cardiovascular BRU, Royal Brompton Hospital, London, UK; NHLI Imperial College, London, UK. Electronic address: c.dimario@rbht.nhs.uk. ·Int J Cardiol · Pubmed #25438201.

ABSTRACT: -- No abstract --