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Coronary Artery Disease: HELP
Articles by James K. Min
Based on 181 articles published since 2008
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Between 2008 and 2019, J. K. Min wrote the following 181 articles about Coronary Artery Disease.
 
+ Citations + Abstracts
Pages: 1 · 2 · 3 · 4 · 5 · 6 · 7 · 8
1 Guideline ACR Appropriateness Criteria 2017

Anonymous3940905 / Akers, Scott R / Panchal, Vandan / Ho, Vincent B / Beache, Garth M / Brown, Richard K J / Ghoshhajra, Brian B / Greenberg, S Bruce / Hsu, Joe Y / Kicska, Gregory A / Min, James K / Stillman, Arthur E / Stojanovska, Jadranka / Abbara, Suhny / Jacobs, Jill E. ·Principal Author, VA Medical Center, Philadelphia, Pennsylvania. Electronic address: akerssco@me.com. · Research Author, Internal Medicine Resident, Henry Ford Allegiance Health, Jackson, Michigan. · Panel Vice-Chair, Uniformed Services University of the Health Sciences, Bethesda, Maryland. · University of Louisville School of Medicine, Louisville, Kentucky. · University Hospital, Ann Arbor, Michigan. · Massachusetts General Hospital, Boston, Massachusetts. · Arkansas Children's Hospital, Little Rock, Arkansas. · Kaiser Permanente, Los Angeles, California. · University of Washington, Seattle, Washington. · Cedars Sinai Medical Center, Los Angeles, California; American College of Cardiology. · Emory University Hospital, Atlanta, Georgia. · University of Michigan Health System, Ann Arbor, Michigan. · Specialty Chair, UT Southwestern Medical Center, Dallas, Texas. · Panel Chair, New York University Medical Center, New York, New York. ·J Am Coll Radiol · Pubmed #28473096.

ABSTRACT: In patients with chronic chest pain in the setting of high probability of coronary artery disease (CAD), imaging has major and diverse roles. First, imaging is valuable in determining and documenting the presence, extent, and severity of myocardial ischemia, hibernation, scarring, and/or the presence, site, and severity of obstructive coronary lesions. Second, imaging findings are important in determining the course of management of patients with suspected chronic myocardial ischemia and better defining those patients best suited for medical therapy, angioplasty/stenting, or surgery. Third, imaging is also necessary to determine the long-term prognosis and likely benefit from various therapeutic options by evaluating ventricular function, diastolic relaxation, and end-systolic volume. Imaging studies are also required to demonstrate other abnormalities, such as congenital/acquired coronary anomalies and severe left ventricular hypertrophy, that can produce angina in the absence of symptomatic coronary obstructive disease due to atherosclerosis. Clinical risk assessment is necessary to determine the pretest probability of CAD. Multiple methods are available to categorize patients as low, medium, or high risk for developing CAD. The American College of Radiology Appropriateness Criteria are evidence-based guidelines for specific clinical conditions that are reviewed annually by a multidisciplinary expert panel. The guideline development and revision include an extensive analysis of current medical literature from peer reviewed journals and the application of well-established methodologies (RAND/UCLA Appropriateness Method and Grading of Recommendations Assessment, Development, and Evaluation or GRADE) to rate the appropriateness of imaging and treatment procedures for specific clinical scenarios. In those instances where evidence is lacking or equivocal, expert opinion may supplement the available evidence to recommend imaging or treatment.

2 Guideline ACCF/AHA/ASE/ASNC/HFSA/HRS/SCAI/SCCT/SCMR/STS 2013 multimodality appropriate use criteria for the detection and risk assessment of stable ischemic heart disease: a report of the American College of Cardiology Foundation Appropriate Use Criteria Task Force, American Heart Association, American Society of Echocardiography, American Society of Nuclear Cardiology, Heart Failure Society of America, Heart Rhythm Society, Society for Cardiovascular Angiography and Interventions, Society of Cardiovascular Computed Tomography, Society for Cardiovascular Magnetic Resonance, and Society of Thoracic Surgeons. 2014

Wolk, Michael J / Bailey, Steven R / Doherty, John U / Douglas, Pamela S / Hendel, Robert C / Kramer, Christopher M / Min, James K / Patel, Manesh R / Rosenbaum, Lisa / Shaw, Leslee J / Stainback, Raymond F / Allen, Joseph M / Anonymous3380779. · ·J Am Coll Cardiol · Pubmed #24355759.

ABSTRACT: The American College of Cardiology Foundation along with key specialty and subspecialty societies, conducted an appropriate use review of common clinical presentations for stable ischemic heart disease (SIHD) to consider use of stress testing and anatomic diagnostic procedures. This document reflects an updating of the prior Appropriate Use Criteria (AUC) published for radionuclide imaging (RNI), stress echocardiography (Echo), calcium scoring, coronary computed tomography angiography (CCTA), stress cardiac magnetic resonance (CMR), and invasive coronary angiography for SIHD. This is in keeping with the commitment to revise and refine the AUC on a frequent basis. A major innovation in this document is the rating of tests side by side for the same indication. The side-by-side rating removes any concerns about differences in indication or interpretation stemming from prior use of separate documents for each test. However, the ratings were explicitly not competitive rankings due to the limited availability of comparative evidence, patient variability, and range of capabilities available in any given local setting. The indications for this review are limited to the detection and risk assessment of SIHD and were drawn from common applications or anticipated uses, as well as from current clinical practice guidelines. Eighty clinical scenarios were developed by a writing committee and scored by a separate rating panel on a scale of 1 to 9, to designate Appropriate, May Be Appropriate, or Rarely Appropriate use following a modified Delphi process following the recently updated AUC development methodology. The use of some modalities of testing in the initial evaluation of patients with symptoms representing ischemic equivalents, newly diagnosed heart failure, arrhythmias, and syncope was generally found to be Appropriate or May Be Appropriate, except in cases where low pre-test probability or low risk limited the benefit of most testing except exercise electrocardiogram (ECG). Testing for the evaluation of new or worsening symptoms following a prior test or procedure was found to be Appropriate. In addition, testing was found to be Appropriate or May Be Appropriate for patients within 90 days of an abnormal or uncertain prior result. Pre-operative testing was rated Appropriate or May Be Appropriate only for patients who had poor functional capacity and were undergoing vascular or intermediate risk surgery with 1 or more clinical risk factors or an organ transplant. The exercise ECG was suggested as an Appropriate test for cardiac rehabilitation clearance or for exercise prescription purposes. Testing in asymptomatic patients was generally found to be Rarely Appropriate, except for calcium scoring and exercise testing in intermediate and high-risk individuals and either stress or anatomic imaging in higher-risk individuals, which were all rated as May Be Appropriate. All modalities of follow-up testing after a prior test or percutaneous coronary intervention (PCI) within 2 years and within 5 years after coronary artery bypass graft (CABG) in the absence of new symptoms were rated Rarely Appropriate. Pre-operative testing for patients with good functional capacity, prior normal testing within 1 year, or prior to low-risk surgery also were found to be Rarely Appropriate. Imaging for an exercise prescription or prior to the initiation of cardiac rehabilitation was Rarely Appropriate except for cardiac rehabilitation clearance for heart failure patients.

3 Guideline ACCF/SCAI/AATS/AHA/ASE/ASNC/HFSA/HRS/SCCM/SCCT/SCMR/STS 2012 appropriate use criteria for diagnostic catheterization: American College of Cardiology Foundation Appropriate Use Criteria Task Force Society for Cardiovascular Angiography and Interventions American Association for Thoracic Surgery American Heart Association, American Society of Echocardiography American Society of Nuclear Cardiology Heart Failure Society of America Heart Rhythm Society, Society of Critical Care Medicine Society of Cardiovascular Computed Tomography Society for Cardiovascular Magnetic Resonance Society of Thoracic Surgeons. 2012

Patel, Manesh R / Bailey, Steven R / Bonow, Robert O / Chambers, Charles E / Chan, Paul S / Dehmer, Gregory J / Kirtane, Ajay J / Wann, L Samuel / Ward, R Parker / Douglas, Pamela S / Patel, Manesh R / Bailey, Steven R / Altus, Philip / Barnard, Denise D / Blankenship, James C / Casey, Donald E / Dean, Larry S / Fazel, Reza / Gilchrist, Ian C / Kavinsky, Clifford J / Lakoski, Susan G / Le, D Elizabeth / Lesser, John R / Levine, Glenn N / Mehran, Roxana / Russo, Andrea M / Sorrentino, Matthew J / Williams, Mathew R / Wong, John B / Wolk, Michael J / Bailey, Steven R / Douglas, Pamela S / Hendel, Robert C / Kramer, Christopher M / Min, James K / Patel, Manesh R / Shaw, Leslee / Stainback, Raymond F / Allen, Joseph M. ·Society for Cardiovascular Angiography and Interventions Representative. ·Catheter Cardiovasc Interv · Pubmed #22678595.

ABSTRACT: The American College of Cardiology Foundation, in collaboration with the Society for Cardiovascular Angiography and Interventions and key specialty and subspecialty societies, conducted a review of common clinical scenarios where diagnostic catheterization is frequently considered. The indications (clinical scenarios) were derived from common applications or anticipated uses, as well as from current clinical practice guidelines and results of studies examining the implementation of noninvasive imaging appropriate use criteria. The 166 indications in this document were developed by a diverse writing group and scored by a separate independent technical panel on a scale of 1 to 9, to designate appropriate use (median 7 to 9), uncertain use (median 4 to 6), and inappropriate use (median 1 to 3). Diagnostic catheterization may include several different procedure components. The indications developed focused primarily on 2 aspects of diagnostic catheterization. Many indications focused on the performance of coronary angiography for the detection of coronary artery disease with other procedure components (e.g., hemodynamic measurements, ventriculography) at the discretion of the operator. The majority of the remaining indications focused on hemodynamic measurements to evaluate valvular heart disease, pulmonary hypertension, cardiomyopathy, and other conditions, with the use of coronary angiography at the discretion of the operator. Seventy-five indications were rated as appropriate, 49 were rated as uncertain, and 42 were rated as inappropriate. The appropriate use criteria for diagnostic catheterization have the potential to impact physician decision making, healthcare delivery, and reimbursement policy. Furthermore, recognition of uncertain clinical scenarios facilitates identification of areas that would benefit from future research. © 2012 Wiley Periodicals, Inc.

4 Guideline ACCF/SCAI/STS/AATS/AHA/ASNC/HFSA/SCCT 2012 appropriate use criteria for coronary revascularization focused update: a report of the American College of Cardiology Foundation Appropriate Use Criteria Task Force, Society for Cardiovascular Angiography and Interventions, Society of Thoracic Surgeons, American Association for Thoracic Surgery, American Heart Association, American Society of Nuclear Cardiology, and the Society of Cardiovascular Computed Tomography. 2012

Anonymous780721 / Patel, Manesh R / Dehmer, Gregory J / Hirshfeld, John W / Smith, Peter K / Spertus, John A / Anonymous790721 / Masoudi, Frederick A / Dehmer, Gregory J / Patel, Manesh R / Smith, Peter K / Chambers, Charles E / Ferguson, T Bruce / Garcia, Mario J / Grover, Frederick L / Holmes, David R / Klein, Lloyd W / Limacher, Marian C / Mack, Michael J / Malenka, David J / Park, Myung H / Ragosta, Michael / Ritchie, James L / Rose, Geoffrey A / Rosenberg, Alan B / Russo, Andrea M / Shemin, Richard J / Weintraub, William S / Anonymous800721 / Wolk, Michael J / Bailey, Steven R / Douglas, Pamela S / Hendel, Robert C / Kramer, Christopher M / Min, James K / Patel, Manesh R / Shaw, Leslee / Stainback, Raymond F / Allen, Joseph M / Anonymous810721 / Anonymous820721 / Anonymous830721 / Anonymous840721 / Anonymous850721 / Anonymous860721 / Anonymous870721 / Anonymous880721. · ·J Thorac Cardiovasc Surg · Pubmed #22424518.

ABSTRACT: The American College of Cardiology Foundation (ACCF), Society for Cardiovascular Angiography and Interventions, Society of Thoracic Surgeons, and the American Association for Thoracic Surgery, along with key specialty and subspecialty societies, conducted an update of the appropriate use criteria (AUC) for coronary revascularization frequently considered. In the initial document, 180 clinical scenarios were developed to mimic patient presentations encountered in everyday practice and included information on symptom status, extent of medical therapy, risk level as assessed by noninvasive testing, and coronary anatomy. This update provides a reassessment of clinical scenarios the writing group felt to be affected by significant changes in the medical literature or gaps from prior criteria. The methodology used in this update is similar to the initial document, and the definition of appropriateness was unchanged. The technical panel scored the clinical scenarios on a scale of 1 to 9. Scores of 7 to 9 indicate that revascularization is considered appropriate and likely to improve patients' health outcomes or survival. Scores of 1 to 3 indicate revascularization is considered inappropriate and unlikely to improve health outcomes or survival. Scores in the mid-range (4 to 6) indicate a clinical scenario for which the likelihood that coronary revascularization will improve health outcomes or survival is uncertain. In general, as seen with the prior AUC, the use of coronary revascularization for patients with acute coronary syndromes and combinations of significant symptoms and/or ischemia is appropriate. In contrast, revascularization of asymptomatic patients or patients with low-risk findings on noninvasive testing and minimal medical therapy are viewed less favorably. The technical panel felt that based on recent studies, coronary artery bypass grafting remains an appropriate method of revascularization for patients with high burden of coronary artery disease (CAD). Additionally, percutaneous coronary intervention may have a role in revascularization of patients with high burden of CAD. The primary objective of the appropriate use criteria is to improve physician decision making and patient education regarding expected benefits from revascularization and to guide future research.

5 Editorial Cardiovascular computed tomographic angiography: Entering into the 5th stage. 2018

Min, James K / Feuchtner, Gudrun M / Villines, Todd C. ·New York-Presbyterian Hospital and the Weill Cornell Medical College, Department of Radiology, 413 E. 69th Street, Suite 108, New York City, NY 10021, United States. Electronic address: jkm2001@med.cornell.edu. · Medical University Innsbruck, Innsbruck, Austria. · Uniformed Services University School of Medicine and the Walter Reed Medical Center, Bethesda, MD, United States. ·J Cardiovasc Comput Tomogr · Pubmed #29759895.

ABSTRACT: -- No abstract --

6 Editorial Look Backwards But Live Forwards. 2017

Min, James K. ·Departments of Radiology and Medicine, Weill Cornell Medical College, New York, New York; Dalio Institute of Cardiovascular Imaging, New York-Presbyterian Hospital, New York, New York. Electronic address: runone123@gmail.com. ·JACC Cardiovasc Imaging · Pubmed #27085450.

ABSTRACT: -- No abstract --

7 Editorial CAD-RADS: A Giant First Step Toward a Common Lexicon? 2016

Chandrashekhar, Y / Min, James K / Hecht, Harvey / Narula, Jagat. ·University of Minnesota School of Medicine, and VA Medical Center, Minneapolis, Minnesota. · Dalio Institute of Cardiovascular Imaging, Weill Cornell Medical College and New York Presbyterian Hospital, New York, New York. · Icahn School of Medicine at Mount Sinai, New York, New York. · Icahn School of Medicine at Mount Sinai, New York, New York. Electronic address: narula@mountsinai.org. ·JACC Cardiovasc Imaging · Pubmed #27609154.

ABSTRACT: -- No abstract --

8 Editorial Assessing Hemodynamically Significant CAD by Difference in Contrast Opacification of CT Angiograms: An Exercise in Seeing and Believing. 2016

Min, James K. ·Departments of Radiology and Medicine, Weill Cornell Medical College, New York, New York; Dalio Institute of Cardiovascular Imaging, New York-Presbyterian Hospital, New York, New York. Electronic address: runone123@gmail.com. ·JACC Cardiovasc Imaging · Pubmed #27372015.

ABSTRACT: -- No abstract --

9 Editorial Diagnosis of Coronary Disease and Icing on the Cake. 2015

Min, James K / Chandrashekhar, Y / Narula, Jagat. ·Departments of Radiology and Medicine, Weill Cornell Medical College, Dalio Institute of Cardiovascular Imaging, New York-Presbyterian Hospital, New York, New York. · University of Minnesota and VA Medical Center, Minneapolis, Minnesota. · Icahn School of Medicine at Mount Sinai, New York, New York. Electronic address: narula@mountsinai.org. ·JACC Cardiovasc Imaging · Pubmed #26381774.

ABSTRACT: -- No abstract --

10 Editorial FFR Derived From Coronary CT Angiography: Solving the Calcification Dilemma of Coronary CT Angiography. 2015

Budoff, Matthew J / Min, James K. ·Los Angeles Biomedical Research Institute, Harbor-UCLA Medical Center, Torrance, California. Electronic address: mbudoff@labiomed.org. · Departments of Radiology and Medicine, Weill Cornell Medical College, New York, New York; Dalio Institute of Cardiovascular Imaging, New York-Presbyterian Hospital, New York, New York. ·JACC Cardiovasc Imaging · Pubmed #26381767.

ABSTRACT: -- No abstract --

11 Editorial Comparing outcomes and costs following cardiovascular imaging: a SPARC…but further illumination is needed. 2014

Villines, Todd C / Min, James K. ·Department of Medicine (Cardiology Service), Walter Reed National Military Medical Center, Bethesda, Maryland. Electronic address: todd.c.villines@health.mil. · Dalio Institute of Cardiovascular Imaging, New York-Presbyterian Hospital and the Weill Cornell Medical College, New York, New York. ·J Am Coll Cardiol · Pubmed #24412452.

ABSTRACT: -- No abstract --

12 Editorial The synergy between percutaneous therapies and noninvasive diagnostic imaging. 2013

Min, James K. ·Departments of Radiology and Medicine, Weill Cornell Medical College and the New York-Presbyterian Hospital, New York, New York. Electronic address: jkm2001@med.cornell.edu. ·JACC Cardiovasc Interv · Pubmed #24156962.

ABSTRACT: -- No abstract --

13 Editorial Diagnostic accuracy of coronary computed tomography angiography in patients post-coronary artery bypass grafting. 2012

Min, James K / Kochar, Minisha. · ·Indian Heart J · Pubmed #22664807.

ABSTRACT: -- No abstract --

14 Editorial The relative nature of a "normal" myocardial perfusion SPECT. 2010

Min, James K / Bell, George W. · ·J Nucl Cardiol · Pubmed #21042900.

ABSTRACT: -- No abstract --

15 Editorial Screening for coronary artery disease in diabetic patients: a commentary. 2009

Berman, Daniel S / Rozanski, Alan / Rana, Jamal S / Shaw, Leslee J / Wong, Nathan D / Min, James K. · ·J Nucl Cardiol · Pubmed #19690936.

ABSTRACT: -- No abstract --

16 Review The Journal of Cardiovascular Computed Tomography year in review - 2018. 2018

Al'Aref, Subhi J / Mrsic, Zorana / Feuchtner, Gudrun / Min, James K / Villines, Todd C. ·Dalio Institute of Cardiovascular Imaging, Weill Cornell Medicine and NewYork-Presbyterian Hospital, New York, NY, USA. · Cardiac CT Program and Cardiovascular Research, Walter Reed National Military Medical Center, Bethesda, MD, USA. · Department of Radiology, Innsbruck Medical University, Innsbruck, Austria. · Cardiac CT Program and Cardiovascular Research, Walter Reed National Military Medical Center, Bethesda, MD, USA. Electronic address: todd.c.villines.mil@mail.mil. ·J Cardiovasc Comput Tomogr · Pubmed #30361179.

ABSTRACT: Since the introduction of ≥64 detector row coronary computed tomography angiography (CCTA) as a noninvasive imaging modality, various clinical trials have established its diagnostic performance and prognostic significance when compared to other anatomic and functional tests for coronary artery disease (CAD). CCTA has been increasingly utilized for a wide range of clinical scenarios, driven by both advances in technology as well as data showing improvement in outcomes. Accumulating evidence has continually refined and supported the central role of CCTA within clinical care, and this year has witnessed continued evolution of the application of CCTA within healthcare and translational research. The purpose of the present review is to summarize the year of the Journal of Cardiovascular Computed Tomography (JCCT), highlighting the evidence base supporting the appropriate application of cardiac computed tomography across numerous clinical domains.

17 Review Machine learning in cardiac CT: Basic concepts and contemporary data. 2018

Singh, Gurpreet / Al'Aref, Subhi J / Van Assen, Marly / Kim, Timothy Suyong / van Rosendael, Alexander / Kolli, Kranthi K / Dwivedi, Aeshita / Maliakal, Gabriel / Pandey, Mohit / Wang, Jing / Do, Virginie / Gummalla, Manasa / De Cecco, Carlo N / Min, James K. ·Dalio Institute of Cardiovascular Imaging, Weill Cornell Medicine, New York, USA. · Division of Cardiovascular Imaging, Medical University of South Carolina, Department of Radiology and Radiological Science, Division of Cardiovascular Imaging, Charleston, SC, USA; University of Groningen, University Medical Center Groningen, Center for Medical Imaging - North East Netherlands, Groningen, The Netherlands. · Division of Cardiovascular Imaging, Medical University of South Carolina, Department of Radiology and Radiological Science, Division of Cardiovascular Imaging, Charleston, SC, USA. · Dalio Institute of Cardiovascular Imaging, Weill Cornell Medicine, New York, USA. Electronic address: jkm2001@med.cornell.edu. ·J Cardiovasc Comput Tomogr · Pubmed #29754806.

ABSTRACT: Propelled by the synergy of the groundbreaking advancements in the ability to analyze high-dimensional datasets and the increasing availability of imaging and clinical data, machine learning (ML) is poised to transform the practice of cardiovascular medicine. Owing to the growing body of literature validating both the diagnostic performance as well as the prognostic implications of anatomic and physiologic findings, coronary computed tomography angiography (CCTA) is now a well-established non-invasive modality for the assessment of cardiovascular disease. ML has been increasingly utilized to optimize performance as well as extract data from CCTA as well as non-contrast enhanced cardiac CT scans. The purpose of this review is to describe the contemporary state of ML based algorithms applied to cardiac CT, as well as to provide clinicians with an understanding of its benefits and associated limitations.

18 Review Diagnostic performance of cardiac imaging methods to diagnose ischaemia-causing coronary artery disease when directly compared with fractional flow reserve as a reference standard: a meta-analysis. 2017

Danad, Ibrahim / Szymonifka, Jackie / Twisk, Jos W R / Norgaard, Bjarne L / Zarins, Christopher K / Knaapen, Paul / Min, James K. ·Department of Radiology, Weill Cornell Medical College, New York, NY, USA. · Dalio Institute of Cardiovascular Imaging, NewYork-Presbyterian Hospital, New York, NY, USA. · Department of Epidemiology and Biostatistics, VU University Medical Center, VU University, Amsterdam, The Netherlands. · Department of Cardiology, Aarhus University Hospital Skejby, Aarhus, Denmark. · Department of Surgery, Stanford University Medical Center, Stanford, CA, USA. · HeartFlow, Inc., Redwood City, CA, USA. · Department of Cardiology, VU University Medical Center, Amsterdam, The Netherlands. ·Eur Heart J · Pubmed #27141095.

ABSTRACT: Aims: The aim of this study was to determine the diagnostic performance of single-photon emission computed tomography (SPECT), stress echocardiography (SE), invasive coronary angiography (ICA), coronary computed tomography angiography (CCTA), fractional flow reserve (FFR) derived from CCTA (FFRCT), and cardiac magnetic resonance (MRI) imaging when directly compared with an FFR reference standard. Method and results: PubMed and Web of Knowledge were searched for investigations published between 1 January 2002 and 28 February 2015. Studies performing FFR in at least 75% of coronary vessels for the diagnosis of ischaemic coronary artery disease (CAD) were included. Twenty-three articles reporting on 3788 patients and 5323 vessels were identified. Meta-analysis was performed for pooled sensitivity, specificity, likelihood ratios (LR), diagnostic odds ratio, and summary receiver operating characteristic curves. In contrast to ICA, CCTA, and FFRCT reports, studies evaluating SPECT, SE, and MRI were largely retrospective, single-centre and with generally smaller study samples. On a per-patient basis, the sensitivity of CCTA (90%, 95% CI: 86-93), FFRCT (90%, 95% CI: 85-93), and MRI (90%, 95% CI: 75-97) were higher than for SPECT (70%, 95% CI: 59-80), SE (77%, 95% CI: 61-88), and ICA (69%, 95% CI: 65-75). The highest and lowest per-patient specificity was observed for MRI (94%, 95% CI: 79-99) and for CCTA (39%, 95% CI: 34-44), respectively. Similar specificities were noted for SPECT (78%, 95% CI: 68-87), SE (75%, 95% CI: 63-85), FFRCT (71%, 95% CI: 65-75%), and ICA (67%, 95% CI: 63-71). On a per-vessel basis, the highest sensitivity was for CCTA (pooled sensitivity, 91%: 88-93), MRI (91%: 84-95), and FFRCT (83%, 78-87), with lower sensitivities for ICA (71%, 69-74), and SPECT (57%: 49-64). Per-vessel specificity was highest for MRI (85%, 79-89), FFRCT (78%: 78-81), and SPECT (75%: 69-80), whereas ICA (66%: 64-68) and CCTA (58%: 55-61) yielded a lower specificity. Conclusions: In this meta-analysis comparing cardiac imaging methods directly to FFR, MRI had the highest performance for diagnosis of ischaemia-causing CAD, with lower performance for SPECT and SE. Anatomic methods of CCTA and ICA yielded lower specificity, with functional assessment of coronary atherosclerosis by SE, SPECT, and FFRCT improving accuracy.

19 Review Role of computed tomography screening for detection of coronary artery disease. 2016

Han, Donghee / Lee, Ji Hyun / Hartaigh, Bríain Ó / Min, James K. ·Department of Radiology, Weill Cornell Medical College, New York, New York; Dalio Institute of Cardiovascular Imaging, New York-Presbyterian Hospital, New York, NY. · Department of Radiology, Weill Cornell Medical College, New York, New York; Dalio Institute of Cardiovascular Imaging, New York-Presbyterian Hospital, New York, NY; Department of Medicine, Weill Cornell Medical College, New York, New York. Electronic address: jkm2001@med.cornell.edu. ·Clin Imaging · Pubmed #26342860.

ABSTRACT: Coronary artery disease (CAD) is a leading cause of morbidity and mortality in Western populations, and the prediction and prevention of CAD is an inherent challenge facing current health care societies. Computed tomography (CT) has emerged as a noninvasive imaging tool in the field of cardiovascular disease. Notably, CT scanning for detection of coronary artery calcium (CAC) has proven useful in predicting adverse cardiovascular outcomes as well as early identification of CAD. In asymptomatic persons undergoing screening for CAD, CAC is well established as a surrogate of CAD risk and has demonstrated incremental benefit over and above traditional risk prediction tools. In addition, a zero CAC score has shown to reflect a substantially lower risk of CAD and may therefore be considered an important marker of CAD protection. Irrespective of screening in the asymptomatic population, CAC scanning has also displayed a beneficial role in the symptomatic population, specifically as gatekeeper in guiding further treatment decision making. Further still, the combination of alternative CT screening strategies such as CT screening for lung cancer with CAC scanning may hold particular promise as an effective screening approach by lowering overall health costs as well as limiting radiation exposure.

20 Review ACR Appropriateness Criteria Acute Nonspecific Chest Pain-Low Probability of Coronary Artery Disease. 2015

Hoffmann, Udo / Akers, Scott R / Brown, Richard K J / Cummings, Kristopher W / Cury, Ricardo C / Greenberg, S Bruce / Ho, Vincent B / Hsu, Joe Y / Min, James K / Panchal, Kalpesh K / Stillman, Arthur E / Woodard, Pamela K / Jacobs, Jill E. ·Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts. Electronic address: uhoffmann@partners.org. · VA Medical Center, Philadelphia, Pennsylvania. · University Hospital, Ann Arbor, Michigan. · Mallinckrodt Institute of Radiology, Washington University School of Medicine, St Louis, Missouri. · Miami Cardiac and Vascular Institute and Baptist Health of South Florida, Miami, Florida. · Arkansas Children's Hospital, Little Rock, Arkansas. · Uniformed Services University of the Health Sciences, Bethesda, Maryland. · Diagnostic Imaging, Los Angeles, California. · Cedars Sinai Medical Center, Los Angeles, California, American College of Cardiology. · University of Cincinnati Hospital, Cincinnati, Ohio. · Emory University Hospital, Atlanta, Georgia. · New York University Medical Center, New York, New York. ·J Am Coll Radiol · Pubmed #26653833.

ABSTRACT: Primary imaging options in patients at low risk for coronary artery disease (CAD) who present with undifferentiated chest pain and without signs of ischemia are functional testing with exercise or pharmacologic stress-based electrocardiography, echocardiography, or myocardial perfusion imaging to exclude myocardial ischemia after rule-out of myocardial infarction and early cardiac CT because of its high negative predictive value to exclude CAD. Although possible, is not conclusive whether triple-rule-out CT (CAD, pulmonary embolism, and aortic dissection) might improve the efficiency of patient management. More advanced noninvasive tests such as cardiac MRI and invasive imaging with transesophageal echocardiography or coronary angiography are rarely indicated. With increased likelihood of noncardiac causes, a number of diagnostic tests, among them ultrasound of the abdomen, MR angiography of the aorta with or without contrast, x-ray rib views, x-ray barium swallow, and upper gastrointestinal series, can also be appropriate. The ACR Appropriateness Criteria are evidence-based guidelines for specific clinical conditions that are reviewed every three years by a multidisciplinary expert panel. The guideline development and review include an extensive analysis of current medical literature from peer-reviewed journals and the application of a well-established consensus methodology (modified Delphi) to rate the appropriateness of imaging and treatment procedures by the panel. In those instances in which evidence is lacking or not definitive, expert opinion may be used to recommend imaging or treatment. This recommendation is based on excellent evidence, including several randomized comparative effectiveness trials and blinded observational cohort studies.

21 Review Dual-energy computed tomography for detection of coronary artery disease. 2015

Danad, Ibrahim / Ó Hartaigh, Bríain / Min, James K. ·a Department of Radiology, Weill Cornell Medical College , Dalio Institute of Cardiovascular Imaging, NewYork-Presbyterian Hospital , New York , NY , USA. ·Expert Rev Cardiovasc Ther · Pubmed #26549789.

ABSTRACT: Recent technological advances in computed tomography (CT) technology have fulfilled the prerequisites for the cardiac application of dual-energy CT (DECT) imaging. By exploiting the unique characteristics of materials when exposed to two different x-ray energies, DECT holds great promise for the diagnosis and management of coronary artery disease. It allows for the assessment of myocardial perfusion to discern the hemodynamic significance of coronary disease and possesses high accuracy for the detection and characterization of coronary plaques, while facilitating reductions in radiation dose. As such, DECT enabled cardiac CT to advance beyond the mere detection of coronary stenosis expanding its role in the evaluation and management of coronary atherosclerosis.

22 Review Noninvasive Fractional Flow Reserve Derived From Coronary CT Angiography: Clinical Data and Scientific Principles. 2015

Min, James K / Taylor, Charles A / Achenbach, Stephan / Koo, Bon Kwon / Leipsic, Jonathon / Nørgaard, Bjarne L / Pijls, Nico J / De Bruyne, Bernard. ·Departments of Radiology and Medicine, Weill Cornell Medical College, New York, New York; Dalio Institute of Cardiovascular Imaging, New York-Presbyterian Hospital, New York, New York. Electronic address: jkm2001@med.cornell.edu. · HeartFlow, Inc., Redwood City, California; Department of Bioengineering, Stanford University, Stanford, California. · Department of Cardiology, Erlangen University Hospital, Erlangen, Germany. · Department of Medicine, Seoul National University Hospital, Seoul, South Korea. · Department of Radiology, St. Paul's Hospital, University of British Columbia, Vancouver, British Columbia, Canada. · Department of Medicine, Weill Cornell Medical Center, New York, New York; Department of Cardiology, Aarhus University Hospital, Skejby, Aarhus, Denmark. · Catharina Hospital, Eindhoven, the Netherlands. · Cardiovascular Center Aalst, OLV Hospital, Aalst, Belgium. ·JACC Cardiovasc Imaging · Pubmed #26481846.

ABSTRACT: Fractional flow reserve derived from coronary computed tomography angiography enables noninvasive assessment of the hemodynamic significance of coronary artery lesions and coupling of the anatomic severity of a coronary stenosis with its physiological effects. Since its initial demonstration of feasibility of use in humans in 2011, a significant body of clinical evidence has developed to evaluate the diagnostic performance of coronary computed tomography angiography-derived fractional flow reserve compared with an invasive fractional flow reserve reference standard. The purpose of this paper was to describe the scientific principles and to review the clinical data of this technology recently approved by the U.S. Food and Drug Administration.

23 Review Noninvasive imaging in coronary artery disease. 2014

Heo, Ran / Nakazato, Ryo / Kalra, Dan / Min, James K. ·Dalio Institute of Cardiovascular Imaging, New York-Presbyterian Hospital and the Weill Cornell Medical College, New York, NY 10021. · St. Luke׳s International Hospital, Tokyo, Japan. · Dalio Institute of Cardiovascular Imaging, New York-Presbyterian Hospital and the Weill Cornell Medical College, New York, NY 10021. Electronic address: jkm2001@med.cornell.edu. ·Semin Nucl Med · Pubmed #25234083.

ABSTRACT: Noninvasive cardiac imaging is widely used to evaluate the presence of coronary artery disease. Recently, with improvements in imaging technology, noninvasive imaging has also been used for evaluation of the presence, severity, and prognosis of coronary artery disease. Coronary CT angiography and MRI of coronary arteries provide an anatomical assessment of coronary stenosis, whereas the hemodynamic significance of a coronary artery stenosis can be assessed by stress myocardial perfusion imaging, such as SPECT/PET and stress MRI. For appropriate use of multiple imaging modalities, the strengths and limitations of each modality are discussed in this review.

24 Review Role of computed tomography for diagnosis and risk stratification of patients with suspected or known coronary artery disease. 2014

Kalra, Dan K / Heo, Ran / Valenti, Valentina / Nakazato, Ryo / Min, James K. ·From the Dalio Institute of Cardiovascular Imaging, New York-Presbyterian Hospital and the Weill Cornell Medical College, New York, NY (D.K.K., R.H., V.V., J.K.M.) · and Cardiovascular Center, St Luke's International Hospital, Tokyo, Japan (R.N.). ·Arterioscler Thromb Vasc Biol · Pubmed #24723554.

ABSTRACT: Cardiac computed tomographic angiography (CCTA) has emerged as a powerful imaging modality for the detection and prognostication of individuals with suspected coronary artery disease. Because calcification of coronary plaque occurs in proportion to the total atheroma volume, the initial diagnostic potential of CCTA focused on the identification and quantification of coronary calcium in low- to intermediate-risk individuals, a finding that tracks precisely with the risk of incident adverse clinical events. Beyond noncontrast detection of coronary calcium, CCTA using iodinated contrast yields incremental information about the degree and distribution of coronary plaques and stenosis, as well as vessel wall morphology and atherosclerotic plaque features. This additive information offers the promise of CCTA to provide a more comprehensive view of total atherosclerotic burden because it relates to myocardial ischemia and future adverse clinical events. Furthermore, emerging data suggest the prognostic and diagnostic importance of stenosis severity detection and atherosclerotic plaque features described by CCTA including positive remodeling, low-attenuation plaque, and spotty calcification, which have been associated with the vulnerability of plaque. We report a summary of the evidence supporting the role of CCTA in the detection of subclinical and clinical coronary artery disease in both asymptomatic and symptomatic patients and discuss the potential of CCTA to augment the identification of at-risk individuals. CCTA and coronary artery calcium scoring offer the ability to improve risk stratification, discrimination, and reclassification of the risk in patients with suspected coronary artery disease and to noninvasively determine the measures of stenosis severity and atherosclerotic plaque features.

25 Review Non-invasive measurement of coronary plaque from coronary CT angiography and its clinical implications. 2013

Dey, Damini / Schuhbaeck, Annika / Min, James K / Berman, Daniel S / Achenbach, Stephan. ·Biomedical Imaging Research Institute, Department of Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, CA, USA. deyd@cshs.org ·Expert Rev Cardiovasc Ther · Pubmed #23984930.

ABSTRACT: Coronary CT angiography (CTA) is increasingly used worldwide for direct, non-invasive evaluation of the coronary arteries. Advances in computed tomography (CT) technology over the last decade have enabled such reliable imaging of the coronary arteries. Beyond arterial stenosis, coronary CTA also permits assessment of atherosclerotic plaque (including plaque burden) and coronary artery remodeling, previously only achievable through invasive means. It has been shown that coronary plaque volumes for non-calcified and mixed plaques and the arterial remodeling index, correlate closely with invasive intravascular ultrasound. Several studies have also shown a strong relationship of adverse plaque features imaged by coronary CTA with acute coronary syndrome, all-cause death, major adverse cardiovascular events and myocardial ischemia. The aim of this review is to summarize current methods for quantitative measurement of atherosclerotic plaque features from coronary CTA and to discuss their clinical implications.

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