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Coronary Artery Disease: HELP
Articles by Sergio Solorio
Based on 2 articles published since 2010
(Why 2 articles?)

Between 2010 and 2020, Sergio Solorio wrote the following 2 articles about Coronary Artery Disease.
+ Citations + Abstracts
1 Article Prognostic Value of Dobutamine Stress Echocardiography in Predicting Major Cardiac Events in Patients with Metabolic Syndrome. 2015

Hernández-González, Martha / Solorio, Sergio / Solís-Jiménez, Manuel Crisóstomo / Rodríguez-Mariscal, Leticia / Murillo-Ortíz, Blanca / Vazquez-Olvera, Sergio. ·Department of Internal Medicine, Hospital General de Zona No.21, Instituto Mexicano del Seguro Social IMSS, León, Guanajuato, Mexico. · Clinical Research Unit, Unidad Médica de Alta Especialidad No.1, Instituto Mexicano del Seguro Social IMSS, León, Guanajuato, Mexico. · Cardiology Department, Unidad Médica de Alta Especialidad No.1, Instituto Mexicano del Seguro Social IMSS, León, Guanajuato, Mexico. ·Rev Invest Clin · Pubmed #26202744.

ABSTRACT: BACKGROUND: The metabolic syndrome increases cardiovascular mortality. We report the mid-term prognostic value of dobutamine echocardiography for metabolic syndrome. PATIENTS AND METHODS: A dobutamine echocardiography protocol was performed in patients aged 18 years of age or older who suffered from chest pain and who were followed-up for two years. The patients were divided in two groups, with and without metabolic syndrome. Statistical analyses were performed using ROC curves and survival analysis; the Begg-Greenes method was used to correct for verification bias. We included 128 patients, 66 with metabolic syndrome and 62 without. RESULTS: Forty-one patients with metabolic syndrome and 36 without had positive dobutamine echocardiography test results (p = 0.77). Coronary artery disease was found in 27 patients with metabolic syndrome and in 29 without metabolic syndrome; percutaneous revascularization was required in 24 and 26 patients, respectively (p = 0.29). Cardiovascular events occurred in 28 patients during follow-up (19 in metabolic syndrome vs. 9 in non-metabolic syndrome; p = 0.17). The odds ratio of major cardiovascular events in the metabolic syndrome group was 5.8 (95% CI: 1.74-19.60); in the control group it was 8.6 (95% CI: 2.53-29.59). CONCLUSION: Dobutamine echocardiography for metabolic syndrome has high sensitivity but is not a determining factor for mid-term prognosis.

2 Article Association between telomere length and C-reactive protein and the development of coronary collateral circulation in patients with coronary artery disease. 2011

Solorio, Sergio / Murillo-Ortíz, Blanca / Hernández-González, Martha / Guillén-Contreras, José / Arenas-Aranda, Diego / Solorzano-Zepeda, Francisco J / Ruiz-Avila, Rene / Mora-Villalpando, Carmen / de la Roca-Chiapas, Jose M / Malacara-Hernández, Juan M. ·Unit of Medical Research, UMAE No. 1 Bajio IMSS, Leon, Guanajuato, Mexico. soloriosergio@aol.com ·Angiology · Pubmed #21441231.

ABSTRACT: BACKGROUND: Coronary collateral circulation is a stabilizer factor in myocardial ischemia. We attempted to establish a link between collateral circulation, C-reactive protein (CRP), and telomere shortening. PATIENTS AND METHODS: A case-control study was performed in patients with (group A) and without (group B) coronary collaterals using coronariography. The patients were males, CRP levels and telomere length in circulating leucocytes were measured; Student t test and logistic regression were used to analyze the data. RESULTS: The study included 40 patients aged 53.9 ± 7.0 years (20 per group). Group A exhibited lower CRP levels (2.76 ± 3.34 vs 4.04 ± 3.38; P = .004); whereas telomere length was shorter in group B (2.3 ± 6.9 kb vs 6.1 ± 5.9 kb; P < .0001). CONCLUSIONS: Collateral circulation was associated with telomere shortening and elevation of CRP levels.