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Coronary Artery Disease: HELP
Articles by Fattouh Youssef
Based on 1 article published since 2010
(Why 1 article?)
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Between 2010 and 2020, Fattouh Youssef wrote the following article about Coronary Artery Disease.
 
+ Citations + Abstracts
1 Article Statin prescription strategies and atherogenic cholesterol goals attainment in Lebanese coronary artery disease patients. 2017

Lama, Soubra / Souraya, Domiati / Youssef, Fattouh. ·Department of Pharmacy Practice, Beirut Arab University, Beirut, Lebanon. l.soubra02@bau.edu.lb. · Department of Pharmacology and Therapeutics, Beirut Arab University, Beirut, Lebanon. · Department of Pharmacy Practice, Beirut Arab University, Beirut, Lebanon. ·Int J Clin Pharm · Pubmed #28523462.

ABSTRACT: Background Current guidelines recommend a low-density lipoprotein cholesterol goal of <1.8 mmol/L (<70 mg/dL) and a non high-density lipoprotein cholesterol (non-HDL-C) goal of <2.6 mmol/L (<00 mg/dL) for coronary artery disease (CAD) patients. Objective This study aimed to describe real-life statin prescription strategies and to assess their effectiveness in terms of LDL-C and non-HDL-C goals attainment in a cohort of CAD patients. Setting Outpatient cardiology specialty clinics located in main Lebanese cities. Methods This is a retrospective crosssectional study. Eligible patients were those who had established CAD, treated with statins and having complete follow-up lipid panel at least 3 months from statin prescription. The following statin prescription strategies were considered in data analysis: prescription of different intensity statin as monotherapy, prescription of a statin in combination with: a low fat diet, another lipid-altering agent and another lipidaltering agent plus a low fat diet. Main outcome measure LDL-C goal attainment for each of the statin prescription strategy. Results Of the 423 CAD statin-treated patients, only 38.5 and 36.6% attained their recommended LDL-C and non-HDL-C goals, respectively. Using a statin in combination with ezetimibe or with another lipid-altering agent plus a low fat diet were significantly associated with LDL-C and non-HDL-C goals attainment. Conclusion Improvement of statin prescription strategies, such as using regular and scheduled dosage of high-intensity statins and combining statin therapy with ezetimibe, is therefore required when managing patients with CAD.