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Depression: HELP
Articles by P. J. M. Westerholm
Based on 1 article published since 2010
(Why 1 article?)

Between 2010 and 2020, P. J. M. Westerholm wrote the following article about Depression.
+ Citations + Abstracts
1 Review Job strain as a risk factor for clinical depression: systematic review and meta-analysis with additional individual participant data. 2017

Madsen, I E H / Nyberg, S T / Magnusson Hanson, L L / Ferrie, J E / Ahola, K / Alfredsson, L / Batty, G D / Bjorner, J B / Borritz, M / Burr, H / Chastang, J-F / de Graaf, R / Dragano, N / Hamer, M / Jokela, M / Knutsson, A / Koskenvuo, M / Koskinen, A / Leineweber, C / Niedhammer, I / Nielsen, M L / Nordin, M / Oksanen, T / Pejtersen, J H / Pentti, J / Plaisier, I / Salo, P / Singh-Manoux, A / Suominen, S / Ten Have, M / Theorell, T / Toppinen-Tanner, S / Vahtera, J / Väänänen, A / Westerholm, P J M / Westerlund, H / Fransson, E I / Heikkilä, K / Virtanen, M / Rugulies, R / Kivimäki, M / Anonymous3181111. ·National Research Centre for the Working Environment,DK-2100 Copenhagen Ø,Denmark. · Finnish Institute of Occupational Health,FI-00250 Helsinki,Finland. · Stress Research Institute, Stockholm University,SE-106 91 Stockholm,Sweden. · Department of Epidemiology and Public Health,University College London,London WC1E 6BT,UK. · Institute of Environmental Medicine,Karolinska Institutet,SE-171 77 Stockholm,Sweden. · Department of Occupational and Environmental Medicine,Bispebjerg University Hospital,DK-2400 Copenhagen,Denmark. · Federal Institute for Occupational Safety and Health (BAuA),D-10317 Berlin,Germany. · INSERM, U1085, Research Institute for Environmental and Occupational Health (IRSET), Epidemiology in Occupational Health and Ergonomics (ESTER) Team, F-49000, Angers,France. · Netherlands Institute of Mental Health and Addiction,3521 VS Utrecht,The Netherlands. · Department of Medical Sociology,University of Düsseldorf,40225 Düsseldorf,Germany. · Institute of Behavioral Sciences,University of Helsinki,FI-00014 Helsinki,Finland. · Department of Health Sciences,Mid Sweden University,SE-851 70 Sundsvall,Sweden. · Department of Public Health,University of Helsinki,FI-00014 Helsinki,Finland. · Unit of Social Medicine,Frederiksberg University Hospital,DK-2000 Copenhagen,Denmark. · The Danish National Centre for Social Research,DK-1052 Copenhagen,Denmark. · The Netherlands Institute for Social Research,2515 XP The Hague,The Netherlands. · Folkhälsan Research Center,FI-00290 Helsinki,Finland. · Occupational and Environmental Medicine,Uppsala University,SE-751 85 Uppsala,Sweden. ·Psychol Med · Pubmed #28122650.

ABSTRACT: BACKGROUND: Adverse psychosocial working environments characterized by job strain (the combination of high demands and low control at work) are associated with an increased risk of depressive symptoms among employees, but evidence on clinically diagnosed depression is scarce. We examined job strain as a risk factor for clinical depression. METHOD: We identified published cohort studies from a systematic literature search in PubMed and PsycNET and obtained 14 cohort studies with unpublished individual-level data from the Individual-Participant-Data Meta-analysis in Working Populations (IPD-Work) Consortium. Summary estimates of the association were obtained using random-effects models. Individual-level data analyses were based on a pre-published study protocol. RESULTS: We included six published studies with a total of 27 461 individuals and 914 incident cases of clinical depression. From unpublished datasets we included 120 221 individuals and 982 first episodes of hospital-treated clinical depression. Job strain was associated with an increased risk of clinical depression in both published [relative risk (RR) = 1.77, 95% confidence interval (CI) 1.47-2.13] and unpublished datasets (RR = 1.27, 95% CI 1.04-1.55). Further individual participant analyses showed a similar association across sociodemographic subgroups and after excluding individuals with baseline somatic disease. The association was unchanged when excluding individuals with baseline depressive symptoms (RR = 1.25, 95% CI 0.94-1.65), but attenuated on adjustment for a continuous depressive symptoms score (RR = 1.03, 95% CI 0.81-1.32). CONCLUSIONS: Job strain may precipitate clinical depression among employees. Future intervention studies should test whether job strain is a modifiable risk factor for depression.