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Depression: HELP
Articles by Jasna Zidverc-Trajkovic
Based on 2 articles published since 2010
(Why 2 articles?)

Between 2010 and 2020, Jasna Zidverc Trajkovic wrote the following 2 articles about Depression.
+ Citations + Abstracts
1 Clinical Trial The efficacy of fluoxetine in BMS-A cross-over study. 2018

Zoric, Bojana / Jankovic, Ljiljana / Kuzmanovic Pficer, Jovana / Zidverc-Trajkovic, Jasna / Mijajlovic, Milija / Stanimirovic, Dragan. ·Department of Periodontology and Oral Medicine, School of Dental Medicine, University of Belgrade, Belgrade, Serbia. · Department for Medical Statistics and Informatics, School of Dental Medicine, University of Belgrade, Belgrade, Serbia. · Institute of Neurology, Clinical Center of Serbia, Belgrade, Serbia. ·Gerodontology · Pubmed #29575009.

ABSTRACT: BACKGROUND: Burning mouth syndrome (BMS) is an intraoral burning or dysaesthetic sensation, recurring daily for more than two hours during the period longer than 3 months. The objective was to evaluate and analyse the efficacy of serotonin reuptake inhibitor fluoxetine on psychological factors, as well as on pain in participants with BMS. METHODS: In a 6-month study, 100 participants with primary and secondary BMS were divided into two groups-fluoxetine and control (placebo) and examined by the dentist and the neurologist. Depression and anxiety were estimated by Hamilton Scale for Depression (HAM-D) and Anxiety (HAM-A) and Beck Depression Inventory (BDI) and the pain intensity by visual analogue scale (VAS). RESULTS: Mean age of the participants was 60.33 in fluoxetine group and 67.4 in control group. Most of the participants were female-74% in the fluoxetine and 78% in the control group. Statistical difference between the fluoxetine and the control group was found in HAM-D results (P < .05). Values of other scales and VAS decreased significantly after the therapy in both groups (P < .05). CONCLUSIONS: Our trial results indicate that fluoxetine therapy not only improves the psychological status of participants with BMS but also fluoxetine decreases the intensity of pain in these patients.

2 Article Baseline characteristic of patients presenting with lacunar stroke and cerebral small vessel disease may predict future development of depression. 2016

Pavlovic, Aleksandra M / Pekmezovic, Tatjana / Zidverc Trajkovic, Jasna / Svabic Medjedovic, Tamara / Veselinovic, Nikola / Radojicic, Aleksandra / Mijajlovic, Milija / Tomic, Gordana / Jovanovic, Zagorka / Norton, Melanie / Sternic, Nada. ·Faculty of Medicine, Neurology Clinic, Clinical Center of Serbia, University of Belgrade, Belgrade, Serbia. · Faculty of Medicine, University of Belgrade, Belgrade, Serbia. ·Int J Geriatr Psychiatry · Pubmed #25821003.

ABSTRACT: OBJECTIVE: Cerebral small vessel disease (SVD) is associated with late-onset depression and increases the risk for depression after stroke. We aimed to investigate baseline predictors of depression after long-term follow-up in patients with SVD, initially presenting with first-ever lacunar stroke, free of depression and cognitive impairment. METHODS: A total of 294 patients with SVD were evaluated 3-5 years after the qualifying event. We analyzed baseline demographic data, vascular risk factors, functional status expressed as a score on modified Rankin Scale (mRS), cognitive status, presence of depression, total number of lacunar infarcts and severity of white matter hyperintensities (WMH) on MRI with Age-Related White Matter Changes scale total score (tARWMC) and Fazekas scale periventricular and deep subcortical scores. RESULTS: On follow-up, depression was registered in 117 (39.8%) SVD patients. At the baseline, patients with depression compared with non-depressed were older (64.4 vs 60.9 years; p = 0.007), had higher mRS score (2.8 ± 0.7 vs 1.5 ± 0.7; p < 0.0001) and had more severe lesions on MRI scales (p < 0.0001 for all parameters). On follow-up, depressed patients more frequently exhibited cognitive decline (75.2% depressed vs 56.5% non-depressed; p = 0.003). No difference was detected in risk factor frequency between groups. Multivariate Cox regression analysis adjusted by age and gender revealed independent predictors of depression: baseline mRS >2 (HR 2.17, 95%CI 1.74-2.72; p < 0.0001) and tARWMC (HR 1.05, 95%CI 1.02-1.09; p = 0.005), and cognitive decline on follow-up (HR 1.80, 95%CI 1.12-2.89; p = 0.015). CONCLUSIONS: Baseline functional status and severity of WMH and development of cognitive decline predict the occurence of late-onset depression in patients with SVD.