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Diabetes Mellitus: HELP
Articles by Barbro Kjellström
Based on 2 articles published since 2010
(Why 2 articles?)

Between 2010 and 2020, B. Kjellström wrote the following 2 articles about Diabetes Mellitus.
+ Citations + Abstracts
1 Article Severe Periodontitis Is Associated with Myocardial Infarction in Females. 2018

Nordendahl, E / Gustafsson, A / Norhammar, A / Näsman, P / Rydén, L / Kjellström, B / Anonymous10630941. ·1 Department of Dental Medicine, Karolinska Institutet, Stockholm, Sweden. · 2 Department of Medicine, Karolinska Institutet, Stockholm, Sweden. · 3 Capio S:t Görans Hospital, Stockholm, Sweden. · 4 Center for Safety Research, KTH Royal Institute of Technology, Stockholm, Sweden. ·J Dent Res · Pubmed #29596754.

ABSTRACT: The aim of the present study was to test the hypothesis that there is a sex difference in the association between periodontitis (PD) and a first myocardial infarction (MI). The analysis in the case-control study was based on 785 patients (147 females and 638 males) with a first MI and 792 matched controls (147 females and 645 males), screened for cardiovascular risk factors and subjected to a panoramic dental X-ray. Periodontal status was defined by alveolar bone loss and diagnosed as no PD (≥80% remaining alveolar bone), mild to moderate PD (66% to 79%), or severe PD (<66%). Logistic regression was used when analyzing PD as a risk factor for MI, adjusting for age, smoking, diabetes, education, and marital status. The mean age was 64 ± 7 y for females and 62 ± 8 y for males. Severe PD was more common in female patients than female controls (14 vs. 4%, P = 0.005), with an increased risk for severe PD among female patients with a first MI (odds ratio [OR] = 3.92, 95% confidence interval [CI] =1.53 to 10.00, P = 0.005), which remained (OR = 3.72, 95% CI = 1.24 to 11.16, P = 0.005) after adjustments. Male patients had more severe PD (7% vs. 4%; P = 0.005) than male controls and an increased risk for severe PD (OR = 1.88, 95% CI = 1.14 to 3.11, P = 0.005), but this association did not remain following adjustment (OR = 1.67, 95% CI = 0.97 to 2.84, NS). Severe PD was associated with MI in both females and males. After adjustments for relevant confounders, this association did, however, remain only in females. These data underline the importance of considering poor dental health when evaluating cardiovascular risk, especially in females.

2 Article Longitudinal development of left ventricular diastolic function in patients with type 2 diabetes. 2014

Venskutonyte, Laura / Jarnert, Christina / Rydén, Lars / Kjellström, Barbro. ·Cardiology Unit, Department of Medicine, Karolinska Institutet, Stockholm, Sweden laura.venskutonyte@ki.se. · Cardiology Unit, Department of Medicine, Karolinska Institutet, Stockholm, Sweden. ·Diabetes Care · Pubmed #25193530.

ABSTRACT: OBJECTIVE: Left ventricular diastolic dysfunction (LVDD) is considered to be common in patients with type 2 diabetes mellitus (T2DM), but information on its progression over time is lacking. We studied the longitudinal development of left ventricular diastolic function (LVDF) and myocardial blood flow reserve in patients with T2DM who were free from clinically detectable cardiovascular disease. RESEARCH DESIGN AND METHODS: The LVDF was assessed in 73 patients with T2DM (mean age 67 ± 7 years; males 51%) on two occasions separated by 6.4 ± 0.8 years. RESULTS: At baseline, LVDD was observed in 23 of the patients (32%). During follow-up, the LVDF normalized in 10 of these patients (43%) and remained unchanged in 13 of them (57%). Of the 50 patients (68%) with normal LVDF at baseline, LVDD developed in 9 (18%). Paired evaluation of myocardial blood volume index was available from 22 patients with LVDD and remained unchanged over time. CONCLUSIONS: The condition of the majority of the investigated patients with LVDD improved or remained stable over a period of 6 years.