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Hypercholesterolemia HELP
Based on 6,340 articles published since 2009
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These are the 6340 published articles about Hypercholesterolemia that originated from Worldwide during 2009-2019.
 
+ Citations + Abstracts
Pages: 1 · 2 · 3 · 4 · 5 · 6 · 7 · 8 · 9 · 10 · 11 · 12 · 13 · 14 · 15 · 16 · 17 · 18 · 19 · 20
1 Guideline Lipid-lowering drugs. 2019

Anonymous4291096. · ·Med Lett Drugs Ther · Pubmed #30845106.

ABSTRACT:

2 Guideline None 2017

Faludi, André Arpad / Izar, Maria Cristina de Oliveira / Saraiva, José Francisco Kerr / Bianco, Henrique Tria / Chacra, Ana Paula Marte / Bertoluci, Marcello Casaccia / Moreira, Rodrigo Oliveira / Turatti, Luiz Alberto Andreotti / Bertolami, Adriana / Sulzbach, Martha L / Schaan, Beatriz D / Valerio, Cynthia Melissa / Bertolami, Marcelo Chiara / Malachias, Marcus Vinícius Bolívar / Vencio, Sérgio / Betti, Roberto Tadeu Barcellos / Fonseca, Francisco Antonio Helfenstein / Salles, João Eduardo Nunes / Hohl, Alexandre. · ·Arq Bras Cardiol · Pubmed #29489927.

ABSTRACT: -- No abstract --

3 Guideline 2017 Focused Update of the 2016 ACC Expert Consensus Decision Pathway on the Role of Non-Statin Therapies for LDL-Cholesterol Lowering in the Management of Atherosclerotic Cardiovascular Disease Risk: A Report of the American College of Cardiology Task Force on Expert Consensus Decision Pathways. 2017

Lloyd-Jones, Donald M / Morris, Pamela B / Ballantyne, Christie M / Birtcher, Kim K / Daly, David D / DePalma, Sondra M / Minissian, Margo B / Orringer, Carl E / Smith, Sidney C. · ·J Am Coll Cardiol · Pubmed #28886926.

ABSTRACT: In 2016, the American College of Cardiology published the first expert consensus decision pathway (ECDP) on the role of non-statin therapies for low-density lipoprotein (LDL)-cholesterol lowering in the management of atherosclerotic cardiovascular disease (ASCVD) risk. Since the publication of that document, additional evidence and perspectives have emerged from randomized clinical trials and other sources, particularly considering the longer-term efficacy and safety of proprotein convertase subtilisin/kexin 9 (PCSK9) inhibitors in secondary prevention of ASCVD. Most notably, the FOURIER (Further Cardiovascular Outcomes Research with PCSK9 Inhibition in Subjects with Elevated Risk) trial and SPIRE-1 and -2 (Studies of PCSK9 Inhibition and the Reduction of Vascular Events), assessing evolocumab and bococizumab, respectively, have published final results of cardiovascular outcomes trials in patients with clinical ASCVD and in a smaller number of high-risk primary prevention patients. In addition, further evidence on the types of patients most likely to benefit from the use of ezetimibe in addition to statin therapy after acute coronary syndrome has been published. Based on results from these important analyses, the ECDP writing committee judged that it would be desirable to provide a focused update to help guide clinicians more clearly on decision making regarding the use of ezetimibe and PCSK9 inhibitors in patients with clinical ASCVD with or without comorbidities. In the following summary table, changes from the 2016 ECDP to the 2017 ECDP Focused Update are highlighted, and a brief rationale is provided. The content of the full document has been changed accordingly, with more extensive and detailed guidance regarding decision making provided both in the text and in the updated algorithms. Revised recommendations are provided for patients with clinical ASCVD with or without comorbidities on statin therapy for secondary prevention. The ECDP writing committee judged that these new data did not warrant changes to the decision pathways and algorithms regarding the use of ezetimibe or PCSK9 inhibitors in primary prevention patients with LDL-C <190 mg/dL with or without diabetes mellitus or patients without ASCVD and LDL-C ≥190 mg/dL not due to secondary causes. Based on feedback and further deliberation, the ECDP writing committee down-graded recommendations regarding bile acid sequestrant use, recommending bile acid sequestrants only as optional secondary agents for consideration in patients intolerant to ezetimibe. For clarification, the writing committee has also included new information on diagnostic categories of heterozygous and homozygous familial hypercholesterolemia, based on clinical criteria with and without genetic testing. Other changes to the original document were kept to a minimum to provide consistent guidance to clinicians, unless there was a compelling reason or new evidence, in which case justification is provided.

4 Guideline [2016 European guidelines on cardiovascular disease prevention in clinical practice. The Sixth Joint Task Force of the European Society of Cardiology and Other Societies on Cardiovascular Disease Prevention in Clinical Practice (constituted by representatives of 10 societies and by invited experts. Developed with the special contribution of the European Association for Cardiovascular Prevention & Rehabilitation]. 2017

Piepoli, Massimo F / Hoes, Arno W / Agewall, Stefan / Albus, Christian / Brotons, Carlos / Catapano, Alberico L / Cooney, Marie-Therese / Corrà, Ugo / Cosyns, Bernard / Deaton, Christi / Graham, Ian / Hall, Michael Stephen / Hobbs, F D Richard / Løchen, Maja-Lisa / Löllgen, Herbert / Marques-Vidal, Pedro / Perk, Joep / Prescott, Eva / Redon, Josep / Richter, Dimitrios J / Sattar, Naveed / Smulders, Yvo / Tiberi, Monica / van der Worp, H Bart / van Dis, Ineke / Verschuren, W M Monique. ·European Society of Cardiology (ESC). · International Society of Behavioural Medicine (ISBM). · WONCA Europe. · European Atherosclerosis Society (EAS). · International Diabetes Federation European Region (IDF Europe). · International Federation of Sport Medicine (FIMS). · European Society of Hypertension (ESH). · European Association for the Study of Diabetes (EASD). · European Stroke Organisation (ESO). · European Heart Network (EHN). ·G Ital Cardiol (Rome) · Pubmed #28714997.

ABSTRACT: -- No abstract --

5 Guideline 2017 Position Paper of the Italian Society for Cardiovascular Prevention (SIPREC) for an Updated Clinical Management of Hypercholesterolemia and Cardiovascular Risk: Executive Document. 2017

Volpe, Massimo / Volpe, Roberto / Gallo, Giovanna / Presta, Vivianne / Tocci, Giuliano / Folco, Emanuela / Peracino, Andrea / Tremoli, Elena / Trimarco, Bruno / Anonymous690907. ·Division of Cardiology, Department of Clinical and Molecular Medicine, Faculty of Medicine and Psychology, Sant'Andrea Hospital, University of Rome Sapienza, Rome, Italy. massimo.volpe@uniroma1.it. · IRCCS Neuromed, Pozzilli, IS, Italy. massimo.volpe@uniroma1.it. · Health and Safety Office, Italian National Research Council, Rome, Italy. · Division of Cardiology, Department of Clinical and Molecular Medicine, Faculty of Medicine and Psychology, Sant'Andrea Hospital, University of Rome Sapienza, Rome, Italy. · IRCCS Neuromed, Pozzilli, IS, Italy. · Italian Heart Foundation-Fondazione Italiana Per il Cuore (FIPC), Milan, Italy. · Division of Cardiology, Department of Advanced Biomedical Sciences, Hypertension Research Centre, University of Napoli "Federico II", Naples, Italy. ·High Blood Press Cardiovasc Prev · Pubmed #28523635.

ABSTRACT: The benefits achieved by implementing cardiovascular prevention strategies in terms of reduced incidence of atherosclerotic diseases and mortality are accepted, worldwide. In particular, the clinical management of hypercholesterolemia has a fundamental role for all preventive strategies, both in primary and secondary prevention, at each stage of cardiovascular risk. Since the net clinical benefit of lipid-lowering therapy largely depends on baseline individual cardiovascular risk profile, the assessment of individual risk is essential to establish type and intensity of both preventive and therapeutic strategies. Thus, the real challenge in a setting of clinical practice is not only to identify whom to treat among individuals at low-to-moderate risk, but mostly how much and how long to treat high or very-high risk patients. This manuscript, which reflects concepts and positions that have been published in a more extensive document of the Italian Society for Cardiovascular Prevention (SIPREC), deals with the diagnostic and therapeutic management of patients with dyslipidaemia, with an evidence-based approach adapted and updated from recent guidelines of the European Society of Cardiology and very recent results of randomized clinical trials. The purpose is to suggest a multidimensional and integrated actions aimed at eliminating or minimizing the impact of cardiovascular diseases and their related disabilities and mortality in patients with hypercholesterolemia.

6 Guideline Joint position statement on "Nutraceuticals for the treatment of hypercholesterolemia" of the Italian Society of Diabetology (SID) and of the Italian Society for the Study of Arteriosclerosis (SISA). 2017

Pirro, M / Vetrani, C / Bianchi, C / Mannarino, M R / Bernini, F / Rivellese, A A. ·Unit of Internal Medicine, Department of Medicine, University of Perugia, Perugia, Italy; Italian Society for the Study of Arteriosclerosis (SISA), Italy. · Department of Clinical Medicine and Surgery, "Federico II" University, Naples, Italy; Italian Society of Diabetology (SID), Italy. · Italian Society of Diabetology (SID), Italy; Unit of Diabetology and Metabolic Diseases, Department of Medical Area "Azienda Ospedaliero-Universitaria Pisana", Pisa, Italy. · Italian Society for the Study of Arteriosclerosis (SISA), Italy; Department of Pharmacy, University of Parma, Parma, Italy. · Department of Clinical Medicine and Surgery, "Federico II" University, Naples, Italy; Italian Society of Diabetology (SID), Italy. Electronic address: rivelles@unina.it. ·Nutr Metab Cardiovasc Dis · Pubmed #27956024.

ABSTRACT: AIM: Evidence showed that LDL-cholesterol lowering is associated with a significant cardiovascular risk reduction. The initial therapeutic approach to hypercholesterolemia includes dietary modifications but the compliance to recommendations is often inadequate. Some dietary components with potential cholesterol-lowering activity are present in small amounts in food. Therefore, in recent years the use of "nutraceuticals" (i.e., nutrients and/or bioactive compounds with potential beneficial effects on human health) has become widespread. Such substances may be added to foods and beverages, or taken as dietary supplements (liquid preparations, tablets, capsules). In the present manuscript, the cholesterol-lowering activity of some nutraceuticals (i.e. fiber, phytosterols, soy, policosanol, red yeast rice and berberine) will be discussed along with: 1) the level of evidence on the cholesterol-lowering efficacy emerging from clinical trial; 2) the possible side effects associated with their use; 3) the categories of patients who could benefit from their use. DATA SYNTHESIS: Based on the current literature, the cholesterol-lowering effect of fiber, phytosterols and red yeast rice is consistent and supported by a good level of evidence. Over berberine, there is sufficient evidence showing significant cholesterol-lowering effects, although the results come from studies carried out almost exclusively in Asian populations. Data on the effects of soy are conflicting and, therefore, the strength of recommendation is quite low. The evidence on policosanol is inconclusive. CONCLUSION: Although health benefits may arise from the use of nutraceuticals with cholesterol-lowering activity, their use might be also associated with possible risks and pitfalls, some of which are common to all nutraceuticals whereas others are related to specific nutraceuticals.

7 Guideline [ANMCO/ISS/AMD/ANCE/ARCA/FADOI/GICR-IACPR/SICI-GISE/SIBioC/SIC/SICOA/SID/SIF/SIMEU/SIMG/SIMI/SISA Consensus document. Hypercholesterolemia and cardiovascular risk: diagnostic and therapeutic pathways in Italy]. 2016

Gulizia, Michele Massimo / Colivicchi, Furio / Ricciardi, Gualtiero / Giampaoli, Simona / Maggioni, Aldo Pietro / Averna, Maurizio / Graziani, Maria Stella / Ceriotti, Ferruccio / Mugelli, Alessandro / Rossi, Francesco / Medea, Gerardo / Parretti, Damiano / Abrignani, Maurizio Giuseppe / Arca, Marcello / Filardi, Pasquale Perrone / Perticone, Francesco / Catapano, Alberico / Griffo, Raffaele / Nardi, Federico / Riccio, Carmine / Di Lenarda, Andrea / Scherillo, Marino / Musacchio, Nicoletta / Panno, Antonio Vittorio / Zito, Giovanni Battista / Campanini, Mauro / Bolognese, Leonardo / Faggiano, Pompilio Massimo / Musumeci, Giuseppe / Pusineri, Enrico / Ciaccio, Marcello / Bonora, Enzo / Cantelli Forti, Giorgio / Ruggieri, Maria Pia / Cricelli, Claudio / Romeo, Francesco / Ferrari, Roberto / Maseri, Attilio. ·Associazione Nazionale Medici Cardiologi Ospedalieri (ANMCO). · Istituto Superiore di Sanità (ISS). · Centro Studi ANMCO. · Società Italiana per lo Studio della Arteriosclerosi (SISA). · Società Italiana di Biochimica Clinica e Biologia Molecolare Clinica (SIBioC). · Società Italiana di Farmacologia (SIF). · Società Italiana di Medicina Generale (SIMG). · Società Italiana di Cardiologia (SIC). · Società Italiana di Medicina Interna (SIMI). · Gruppo Italiano di Cardiologia Riabilitativa e Preventiva (GICR-IACPR). · Associazione Medici Diabetologi (AMD). · Cardiologia Italiana del Territorio (ANCE). · Associazioni Regionali Cardiologi Ambulatoriali (ARCA). · Federazione delle Associazioni dei Dirigenti Ospedalieri Internisti (FADOI). · Federazione Italiana di Cardiologia (FIC). · Società Italiana di Cardiologia Interventistica (SICI-GISE). · Società Italiana Cardiologia Ospedalità Accreditata (SICOA). · Società Italiana di Diabetologia (SID). · Società Italiana di Medicina di Emergenza-Urgenza (SIMEU). · Fondazione "per il Tuo cuore" HCF Onlus. ·G Ital Cardiol (Rome) · Pubmed #27312138.

ABSTRACT: Atherosclerotic cardiovascular disease still represents the leading cause of death in western countries. A wealth of scientific evidence demonstrates that increased blood cholesterol levels have a major impact on the outbreak and progression of atherosclerotic plaques. Moreover, several cholesterol-lowering pharmacological agents, including statins and ezetimibe, have proven effective in improving clinical outcomes. This document is focused on the clinical management of hypercholesterolemia and has been conceived by 16 Italian medical associations with the support of the Italian National Institute of Health. The authors have considered with particular attention the role of hypercholesterolemia in the genesis of atherosclerotic cardiovascular disease. Besides, the implications of high cholesterol levels in the definition of the individual cardiovascular risk profile have been carefully analyzed, while all available therapeutic options for blood cholesterol reduction and cardiovascular risk mitigation have been considered. Finally, this document outlines the diagnostic and therapeutic pathways for the clinical management of patients with hypercholesterolemia.

8 Guideline [ANMCO Position paper: Clinical management of hypercholesterolemia in patients with acute coronary syndrome]. 2016

Colivicchi, Furio / Gulizia, Michele Massimo / Arca, Marcello / Abrignani, Maurizio Giuseppe / Perna, Gian Piero / Mureddu, Gian Francesco / Nardi, Federico / Riccio, Carmine / Anonymous6540871. ·U.O.C. Cardiologia, Ospedale S. Filippo Neri, Roma. · U.O.C. Cardiologia, Ospedale Garibaldi-Nesima, Azienda di Rilievo Nazionale e Alta Specializzazione "Garibaldi", Catania. · Centro Aterosclerosi, Policlinico Umberto I, Sapienza Università di Roma, Roma. · U.O.C. Cardiologia, Ospedale Civile Sant'Antonio Abate, Erice (TP). · U.O.C. Cardiologia, Azienda Ospedaliero-Universitaria "Ospedali Riuniti", Ancona. · U.O.C. Cardiologia, A.O. San Giovanni-Addolorata, Roma. · U.O.C. Cardiologia, Ospedale Castelli, Verbania. · U.O.C. Cardiologia e Riabilitazione Cardiologica, A.O. Sant'Anna e San Sebastiano, Caserta. ·G Ital Cardiol (Rome) · Pubmed #27311088.

ABSTRACT: LDL-cholesterol (LDL-C) reduction after acute coronary syndromes (ACS) is associated with a significant reduction in ischemic recurrences. Accordingly, international guidelines recommend a reduction of LDL-C below 70 mg/dl in ACS patients. Such a result can be accomplished by using high intensity statins, possibly associated with ezetimibe in selected cases. This document outlines the management strategies that can be consistently implemented in clinical practice in order to achieve and maintain guideline-recommended therapeutic goals.

9 Guideline [Severe hypercholesterolaemia--when to use the proprotein convertase subtilisin-kexin type 9 protease inhibitors (PCSK9 inhibitors)? Polish Society of Cardiology experts' group statement]. 2016

Cybulska, Barbara / Gaciong, Zbigniew / Hoffman, Piotr / Jankowski, Piotr / Kłosiewicz-Latoszek, Longina / Kaźmierczak, Jarosław / Mitręga, Katarzyna / Opolski, Grzegorz / Pająk, Andrzej / Ponikowski, Piotr / Rynkiewicz, Andrzej / Stępińska, Janina / Średniawa, Beata / Kalarus, Zbigniew. ·Instytut Żywności i Żywienia. barbara.cybulska@wp.pl. ·Kardiol Pol · Pubmed #27098076.

ABSTRACT: The severe hypercholesterolaemia can be recognised when low density lipoprotein cholesterol (LDL-C) serum levels are equal to or above 5 mmol/L (≥ 190 mg/dL). The prevalence of LDL-C ≥ 5 mmol/L is 3.8% in Polish population aged 18-79 years. Among these adults there are patients with familial hypercholesterolaemia (FH). According to meta-analysis of 6 Polish population surveys prevalence of heterozygous FH (HeFH) diagnosed using Dutch Lipid Clinic criteria is 0.4% (95% Cl 0.28-0.53%) in men and women aged 20-74 years, i.e. one in every 250 people. As HeFH is a wellknown cause of premature coronary heart disease the rigorous treatment targets for LDL-C have been established in clinical guidelines. Their achievements, even with a high dose of high efficacy statin therapy is difficult or even impossible. New strong hypolipidaemic drugs i.e. PCSK9 inhibitors have been initiated against this chalange. Both drugs, evolocumab and alirocumab, have been extensively studied in numerous phase 2 and phase 3 trials. Fewer studies with bococizumab are available until now. The PCSK9 inhibitors, as monotherapy as well in combination with statins were associated with mean LDL-C reduction about 60%. It means that the majority of patients (70-90%) with severe hypercholesterolaemia (including HeFH), treated with statins, after addition of PCSK9 inhibitors were able to achieve an LDL-C < 2.5 mmol/L (< 100 mg/dL) or < 1.8 mmol/L (< 70 mg/dL) level. Another group of patients who may benefit from PCSK9 inhibitors include those who need lipid lowering therapy, but who are statin intolerant, especially because of statin-associated muscle symptoms (SAMS). In our statement we have accepted the diagnosis of SAMS proposed recently by European Atherosclerosis Society. Today the longest clinical trial with evolocumab (11 months) was the open OSLER study, and with alirocumab ODYSSEY LONG TERM (78 weeks). In the first one the reduction of cardiovascular events by 53% (95% Cl 22-72%) was observed, and in the second one by 48% (10-69%). Neurocognitive events were reported more frequently with both drugs than with placebo. This adverse effect will be the subject of observation in ongoing studies. We still await the results of 4 ongoing large placebo controlled phase 3 trials investigating whether PCSK9 inhibitors on background of statin therapy reduce cardiovascular events. Meanwhile evolocumab, as well as alirocumab have been accepted to use in clinical practice by European Medicine Agency. In this situation the experts of Polish Society of Cardiology have prepared the statement on the use PCSK9 inhibitors with indication in the first place for HeFH patients, statin intolerant and those at high risk who are not able to reach LDL-C target level with a high potent high dose statin.

10 Guideline Application of New Cholesterol Guidelines to the Korean Adult Diabetic Patients. 2015

Kim, Bu Kyung / Kim, Hyeon Chang / Ha, Kyoung Hwa / Kim, Dae Jung. ·Department of Internal Medicine, Kosin University College of Medicine, Busan, Korea. · Department of Preventive Medicine, Yonsei University College of Medicine, Seoul, Korea. · Cardiovascular and Metabolic Disease Etiology Research Center, Ajou University School of Medicine, Suwon, Korea. · Cardiovascular and Metabolic Disease Etiology Research Center, Ajou University School of Medicine, Suwon, Korea. ; Department of Endocrinology and Metabolism, Ajou University School of Medicine, Suwon, Korea. ·J Korean Med Sci · Pubmed #26539005.

ABSTRACT: The American College of Cardiology and the American Heart Association (ACC/AHA) 2013 joint guidelines for the treatment of hypercholesterolemia expand the indications for statin therapy. This study was performed to estimate the numbers of diabetic patients indicated for statin therapy according to the Third Adult Treatment Panel (ATP-III) of the National Cholesterol Education Program guidelines and the new ACC/AHA guidelines in Korea. We analyzed the data from the Korea National Health and Nutrition Examination Survey (KNHANES) 2010-2012. Patients with diabetes over 30 yr of age were analyzed by the two guidelines. Of the total 1,975 diabetic patients, only 377 (19.1%) were receiving drugs for dyslipidemia. Among 1,598 patients who had not taken any medications for dyslipidemia, 65.6% would be indicated for statin therapy according to the ATP-III guidelines. When we apply the new guidelines, 94.3% would be eligible for statin therapy. Among the total diabetic patients, the new guidelines, compared with the ATP-III guidelines, increase the number eligible for statin therapy from 53.1% to 76.2%. The new guidelines would increase the indication for statin therapy for most diabetic patients. At present, many diabetic patients do not receive appropriate statin therapy. Therefore efforts should be made to develop the Korean guidelines and to ensure that more diabetic patients receive appropriate statin therapy.

11 Guideline The new cholesterol treatment guidelines from the American College of Cardiology/American Heart Association, 2013: what clinicians need to know. 2014

Lim, Tanna H / Orija, Israel B / Pearlman, Brian L / Anonymous4450811 / Anonymous4460811. ·Department of Internal Medicine, Atlanta Medical Center, Atlanta, GA. tannalim@yahoo.com. ·Postgrad Med · Pubmed #25387212.

ABSTRACT: The new American College of Cardiology/American Heart Association blood cholesterol guidelines of 2013 are the first major revision of cholesterol therapy guidance in over a decade. Commonly used low-density lipoprotein cholesterol (LDL-C) target goals have been abrogated in favor of intensity of statin therapy, more in line with data from randomized clinical trials. Four groups of adult patients have been identified from these studies who will most benefit from statins: patients with atherosclerotic cardiovascular disease (ASCVD); patients with primary elevations of LDL-C ≥ 190 mg/dL; diabetic patients between age 40 and 75 years without ASCVD whose LDL-C is between 70 and 189 mg/dL; and patients between age 40 and 75 years without ASCVD or diabetes with LDL-C between 70 and 189 mg/dL and an estimated 10-year ASCVD risk of 7.5% or higher. This last primary prevention group has engendered the most controversy because the newly recommended risk calculator may overestimate risk or the 7.5% threshold may be too low, thereby subjecting too many patients to statins unnecessarily. This review summarizes the latest guidelines and pertinent evidence, and provides case examples to help clinicians familiarize themselves with the new recommendations.

12 Guideline Cardiac risk factors: new cholesterol and blood pressure management guidelines. 2014

Anthony, David / George, Paul / Eaton, Charles B. ·Memorial Hospital of Rhode Island, 111 Brewster St., Pawtucket, RI 02903, USA. david_anthony@brown.edu · Warren Alpert Medical School of Brown University, 222 Richmond Street, Providence, RI 02903, USA. Paul-George@Brown.edu · Warren Alpert Medical School of Brown University, 222 Richmond Street, Providence, RI 02903, USA. Charles_Eaton@Brown.edu ·FP Essent · Pubmed #24936717.

ABSTRACT: The 2013 American College of Cardiology/American Heart Association cholesterol guidelines depart from low-density lipoprotein (LDL) treatment targets and recommend treating four specific patient groups with statins. Statins are the only cholesterol-lowering drugs with randomized trial evidence of benefit for preventing atherosclerotic cardiovascular disease (ASCVD). The groups are patients with clinical ASCVD; patients ages 40 to 75 years with diabetes and LDL of 70 to 189 mg/dL but no clinical ASCVD; patients 21 years or older with LDL levels of 190 mg/dL or higher; and patients ages 40 to 75 years with LDL of 70 to 189 mg/dL without clinical ASCVD or diabetes but with 10-year ASCVD risk of 7.5% or higher. Ten-year ASCVD risk may be calculated using the Pooled Cohort Equations. The Eighth Joint National Committee (JNC 8) guidelines for blood pressure management recommend a blood pressure goal of less than 140/90 mm Hg for all adults except those 60 years or older. For the latter group, the JNC 8 recommends a systolic blood pressure goal of less than 150 mm Hg. In another notable change from prior guidelines, the JNC 8 recommends relaxing the systolic blood pressure goal for patients with diabetes and chronic kidney disease to less than 140 mm Hg from less than 130 mm Hg.

13 Guideline [New thought from American new guideline on the treatment of blood cholesterol]. 2014

Zhao, Shuiping / Peng, Daoquan / Yu, Bilian / Huang, Xiansheng / Hu, Dayi / Shi, Xubo. · ·Zhonghua Xin Xue Guan Bing Za Zhi · Pubmed #24735622.

ABSTRACT: -- No abstract --

14 Guideline New AHA and ACC guidelines on the treatment of blood cholesterol to reduce atherosclerotic cardiovascular risk. 2014

Klose, Gerald / Beil, Frank Ulrich / Dieplinger, Hans / von Eckardstein, Arnold / Föger, Bernhard / Gouni-Berthold, Ioanna / Heigl, Franz / Koenig, Wolfgang / Kostner, Gert M / Landmesser, Ulf / Laufs, Ulrich / Leistikow, Frank / März, Winfried / Noll, Georg / Parhofer, Klaus G / Paulweber, Bernhard / Riesen, Walter F / Schaefer, Jürgen R / Steinhagen-Thiessen, Elisabeth / Steinmetz, Armin / Toplak, Hermann / Wanner, Christoph / Windler, Eberhard / Anonymous4800787. ·Practice for Internal Medicine, Gastroenterology, Cardiology and Preventive Medicine, Bremen, Germany. ·Wien Klin Wochenschr · Pubmed #24615676.

ABSTRACT: After the publication of the new guidelines of the European Society of Cardiology and the European Atherosclerosis Society for the prevention and treatment of dyslipidemias (Eur Heart J 32:1769-1818, 2011; Eur Heart J 33:1635-1701, 2012), a group of authors has recently published on behalf of the American Heart Association and the American College of Cardiology guidelines on the treatment of blood cholesterol to reduce atherosclerotic cardiovascular risk (Circulation 2013). These new guidelines are supposed to replace the until now widely accepted, at least in the USA, recommendations of the National Cholesterol Education Program Adult Treatment Panel III from the years 2002 (Circulation 106:3143-3421, 2002) and 2004 (Circulation 110:227-39, 2004). Furthermore, they claim to be based mainly on hard evidence derived from the interpretation of results of prospective randomized controlled trials. This Joint Position Statement of the Society for the Prevention of Cardiovascular Diseases e.V. (D.A.CH), the Austrian Atherosclerosis Society and the Working Group on Lipids and Atherosclerosis (AGLA) of the Swiss Society of Cardiology concludes that the use of individualized prevention strategies based on specific indications and LDL cholesterol target concentrations, a strategy whose worth has been widely proven and accepted for more than a decade in Europe, should not be given up.

15 Guideline Treatment of blood cholesterol to reduce atherosclerotic cardiovascular disease risk in adults: synopsis of the 2013 American College of Cardiology/American Heart Association cholesterol guideline. 2014

Stone, Neil J / Robinson, Jennifer G / Lichtenstein, Alice H / Goff, David C / Lloyd-Jones, Donald M / Smith, Sidney C / Blum, Conrad / Schwartz, J Sanford / Anonymous1570783. · ·Ann Intern Med · Pubmed #24474185.

ABSTRACT: DESCRIPTION: In November 2013, the American College of Cardiology and American Heart Association (ACC/AHA) released a clinical practice guideline on the treatment of blood cholesterol to reduce cardiovascular risk in adults. This synopsis summarizes the major recommendations. METHODS: In 2008, the National Heart, Lung, and Blood Institute convened the Adult Treatment Panel (ATP) IV to update the 2001 ATP-III cholesterol guidelines using a rigorous process to systematically review randomized, controlled trials (RCTs) and meta-analyses of RCTs that examined cardiovascular outcomes. The panel commissioned independent systematic evidence reviews on low-density lipoprotein cholesterol and non-high-density lipoprotein cholesterol goals in secondary and primary prevention and the effect of lipid drugs on atherosclerotic cardiovascular disease events and adverse effects. In September 2013, the panel's draft recommendations were transitioned to the ACC/AHA. RECOMMENDATIONS: This synopsis summarizes key features of the guidelines in 8 areas: lifestyle, groups shown to benefit from statins, statin safety, decision making, estimation of cardiovascular disease risk, intensity of statin therapy, treatment targets, and monitoring of statin therapy.

16 Guideline 2013 ACC/AHA guideline on the treatment of blood cholesterol to reduce atherosclerotic cardiovascular risk in adults: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. 2014

Stone, Neil J / Robinson, Jennifer G / Lichtenstein, Alice H / Bairey Merz, C Noel / Blum, Conrad B / Eckel, Robert H / Goldberg, Anne C / Gordon, David / Levy, Daniel / Lloyd-Jones, Donald M / McBride, Patrick / Schwartz, J Sanford / Shero, Susan T / Smith, Sidney C / Watson, Karol / Wilson, Peter W F / Anonymous5090775. · ·J Am Coll Cardiol · Pubmed #24239923.

ABSTRACT: -- No abstract --

17 Guideline 2013 ACC/AHA guideline on the treatment of blood cholesterol to reduce atherosclerotic cardiovascular risk in adults: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. 2014

Stone, Neil J / Robinson, Jennifer G / Lichtenstein, Alice H / Bairey Merz, C Noel / Blum, Conrad B / Eckel, Robert H / Goldberg, Anne C / Gordon, David / Levy, Daniel / Lloyd-Jones, Donald M / McBride, Patrick / Schwartz, J Sanford / Shero, Susan T / Smith, Sidney C / Watson, Karol / Wilson, Peter W F / Eddleman, Karen M / Jarrett, Nicole M / LaBresh, Ken / Nevo, Lev / Wnek, Janusz / Anderson, Jeffrey L / Halperin, Jonathan L / Albert, Nancy M / Bozkurt, Biykem / Brindis, Ralph G / Curtis, Lesley H / DeMets, David / Hochman, Judith S / Kovacs, Richard J / Ohman, E Magnus / Pressler, Susan J / Sellke, Frank W / Shen, Win-Kuang / Smith, Sidney C / Tomaselli, Gordon F / Anonymous1990775. · ·Circulation · Pubmed #24222016.

ABSTRACT: -- No abstract --

18 Guideline [V Brazilian Guidelines on Dyslipidemias and Prevention of Atherosclerosis]. 2013

Xavier, H T / Izar, M C / Faria Neto, J R / Assad, M H / Rocha, V Z / Sposito, A C / Fonseca, F A / dos Santos, J E / Santos, R D / Bertolami, M C / Faludi, A A / Martinez, T L R / Diament, J / Guimarães, A / Forti, N A / Moriguchi, E / Chagas, A C P / Coelho, O R / Ramires, J A F. · ·Arq Bras Cardiol · Pubmed #24217493.

ABSTRACT: -- No abstract --

19 Guideline European Guidelines on cardiovascular disease prevention in clinical practice (version 2012). The Fifth Joint Task Force of the European Society of Cardiology and Other Societies on Cardiovascular Disease Prevention in Clinical Practice (constituted by representatives of nine societies and by invited experts). 2012

Perk, Joep / De Backer, Guy / Gohlke, Helmut / Graham, Ian / Reiner, Zeljko / Verschuren, Monique / Albus, Christian / Benlian, Pascale / Boysen, Gudrun / Cifkova, Renata / Deaton, Christi / Ebrahim, Shah / Fisher, Miles / Germano, Giuseppe / Hobbs, Richard / Hoes, Arno / Karadeniz, Sehnaz / Mezzani, Alessandro / Prescott, Eva / Ryden, Lars / Scherer, Martin / Syvänne, Mikko / Scholte op Reimer, Wilma J M / Vrints, Christiaan / Wood, David / Zamorano, Jose Luis / Zannad, Faiez / Anonymous1580725 / Anonymous1590725. ·School of Health and Caring Sciences, Linnaeus University, Stagneliusgatan 14, Kalmar, Sweden. joep.perk@lnu.se ·Eur Heart J · Pubmed #22555213.

ABSTRACT: -- No abstract --

20 Guideline [Recommendations for hypercholesterolemic children]. 2011

Luc, Gérald / Girardet, Jean-Philippe / Bruckert, Éric / Rieu, Daniel / Farnier, Michel / Darmaun, Dominique / Anonymous13100688 / Anonymous13110688. ·Nouvelle société française d’athérosclérose. gerald.luc@univ-lille2.fr ·Presse Med · Pubmed #21391309.

ABSTRACT: Some of hypercholesterolemias observed in childhood have a high risk of premature cardiovascular diseases. The monogenic dominantly inherited hypercholesterolemias such as the familial hypercholesterolemia due to mutations on LDL receptor gene corresponds to these diseases. This article, jointly elaborated by the Nouvelle Société Française d’Athérosclérose together with the Nutrition committee of the Société Française de Pédiatrie, is to propose recommendations for a screening strategy and for management of hypercholesterolemia in children. The approach of these high-risk inherited hypercholesterolemia is specified and the dietary management, the indications and supervision of lipid lowering drug therapy in children are discussed.

21 Guideline [Recommendations for children with hypercholesterolemia]. 2011

Girardet, J-P / Luc, G / Rieu, D / Bruckert, E / Darmaun, D / Farnier, M / Anonymous2240681 / Anonymous2250681. ·Comité de nutrition de la Société française de pédiatrie, 75012 Paris, France. jean-philippe.girardet@trs.aphp.fr ·Arch Pediatr · Pubmed #21145715.

ABSTRACT: Some cases of hypercholesterolemia observed in childhood present a high risk of premature cardiovascular disease, such as in monogenic dominantly inherited hypercholesterolemia, particularly familial hypercholesterolemia due to mutations on the LDL receptor gene. This article, jointly written by the Société Française de Pédiatrie Nutrition Committee and the Nouvelle Société Française d'Athérosclérose, proposes recommendations for a screening strategy and management of childhood hypercholesterolemia. A practical approach to high-risk cases of inherited hypercholesterolemia is detailed and the dietary management, indications, and supervision of lipid-lowering drug therapy in children are discussed.

22 Guideline [Expert recommendations on attaining the goal for treatment of hypercholesterolemia in clinical practice]. 2010

Anonymous2830666. · ·Zhonghua Xin Xue Guan Bing Za Zhi · Pubmed #20654070.

ABSTRACT: -- No abstract --

23 Editorial Problems that Physicians should Notice for Better Treatment of Hypercholesterolemia in Japan. 2019

Fujioka, Yoshio. ·Division of Clinical Nutrition, Faculty of Nutrition, Kobe Gakuin University. ·J Atheroscler Thromb · Pubmed #30210088.

ABSTRACT: -- No abstract --

24 Editorial Postprandial Hyperlipemia is an Indication for Additional Risk in Sitosterolemia. 2018

Ito, Misa / Ikewaki, Katsunori. ·Division of Anti-aging and Vascular Medicine, Department of Internal Medicine, National Defense Medical College. · Saha Cardiovascular Research Center, University of Kentucky College of Medicine. ·J Atheroscler Thromb · Pubmed #30305464.

ABSTRACT: -- No abstract --

25 Editorial A Novel Cause of Familial Hypercholesterolemia: PCSK9 Gene Duplication. 2018

Paquette, Martine / Baass, Alexis. ·Lipids, Nutrition and Cardiovascular Prevention Clinic, Montreal Clinical Research Institute, Québec, Canada. · Lipids, Nutrition and Cardiovascular Prevention Clinic, Montreal Clinical Research Institute, Québec, Canada; Department of Medicine, Division of Experimental Medicine, McGill University, Québec, Canada; Department of Medicine, Division of Medical Biochemistry, McGill University, Québec, Canada. Electronic address: alexis.baass@ircm.qc.ca. ·Can J Cardiol · Pubmed #30269825.

ABSTRACT: -- No abstract --

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