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Hypertension: HELP
Articles by Faraz Pathan
Based on 2 articles published since 2010
(Why 2 articles?)
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Between 2010 and 2020, Faraz Pathan wrote the following 2 articles about Hypertension.
 
+ Citations + Abstracts
1 Editorial Back to the Future: Mitral Annular Plane Systolic Excursion on Cardiac Magnetic Resonance. 2019

Pathan, Faraz / Negishi, Kazuaki. ·Nepean Clinical School, Sydney University, Sydney, New South Wales, Australia; Department of Cardiology Nepean Hospital, Sydney, New South Wales, Australia; Charles Perkins Centre, Sydney University, Sydney, New South Wales, Australia. Electronic address: faraz.pathan@sydney.edu.au. · Nepean Clinical School, Sydney University, Sydney, New South Wales, Australia; Charles Perkins Centre, Sydney University, Sydney, New South Wales, Australia; Menzies Institute for Medical Research, University of Tasmania, Hobart, Tasmania, Australia. ·JACC Cardiovasc Imaging · Pubmed #30660527.

ABSTRACT: -- No abstract --

2 Article Importance of Calibration Method in Central Blood Pressure for Cardiac Structural Abnormalities. 2016

Negishi, Kazuaki / Yang, Hong / Wang, Ying / Nolan, Mark T / Negishi, Tomoko / Pathan, Faraz / Marwick, Thomas H / Sharman, James E. ·Menzies Institute for Medical Research, University of Tasmania, Hobart, Tasmania, Australia. Kazuaki.Negishi@utas.edu.au. · Menzies Institute for Medical Research, University of Tasmania, Hobart, Tasmania, Australia. ·Am J Hypertens · Pubmed #27085076.

ABSTRACT: BACKGROUND: Central blood pressure (CBP) independently predicts cardiovascular risk, but calibration methods may affect accuracy of central systolic blood pressure (CSBP). Standard central systolic blood pressure (Stan-CSBP) from peripheral waveforms is usually derived with calibration using brachial SBP and diastolic BP (DBP). However, calibration using oscillometric mean arterial pressure (MAP) and DBP (MAP-CSBP) is purported to provide more accurate representation of true invasive CSBP. This study sought to determine which derived CSBP could more accurately discriminate cardiac structural abnormalities. METHODS: A total of 349 community-based patients with risk factors (71±5years, 161 males) had CSBP measured by brachial oscillometry (Mobil-O-Graph, IEM GmbH, Stolberg, Germany) using 2 calibration methods: MAP-CSBP and Stan-CSBP. Left ventricular hypertrophy (LVH) and left atrial dilatation (LAD) were measured based on standard guidelines. RESULTS: MAP-CSBP was higher than Stan-CSBP (149±20 vs. 128±15mm Hg, P < 0.0001). Although they were modestly correlated (rho = 0.74, P < 0.001), the Bland-Altman plot demonstrated a large bias (21mm Hg) and limits of agreement (24mm Hg). In receiver operating characteristic (ROC) curve analyses, MAP-CSBP significantly better discriminated LVH compared with Stan-CSBP (area under the curve (AUC) 0.66 vs. 0.59, P = 0.0063) and brachial SBP (0.62, P = 0.027). Continuous net reclassification improvement (NRI) (P < 0.001) and integrated discrimination improvement (IDI) (P < 0.001) corroborated superior discrimination of LVH by MAP-CSBP. Similarly, MAP-CSBP better distinguished LAD than Stan-CSBP (AUC 0.63 vs. 0.56, P = 0.005) and conventional brachial SBP (0.58, P = 0.006), whereas Stan-CSBP provided no better discrimination than conventional brachial BP (P = 0.09). CONCLUSIONS: CSBP is calibration dependent and when oscillometric MAP and DBP are used, the derived CSBP is a better discriminator for cardiac structural abnormalities.