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Infertility: HELP
Articles by Anonymous90869
Based on 1 article published since 2008
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Between 2008 and 2019, Anonymous90869 wrote the following article about Infertility.
 
+ Citations + Abstracts
1 Guideline Committee Opinion No. 663 Summary: Aromatase Inhibitors in Gynecologic Practice. 2016

Anonymous90869. · ·Obstet Gynecol · Pubmed #27214185.

ABSTRACT: Aromatase inhibitors have been used for the treatment of breast cancer, ovulation induction, endometriosis, and other estrogen-modulated conditions. For women with breast cancer, bone mineral density screening is recommended with long-term aromatase inhibitor use because of risk of osteoporosis due to estrogen deficiency. Based on long-term adverse effects and complication safety data, when compared with tamoxifen, aromatase inhibitors are associated with a reduced incidence of thrombosis, endometrial cancer, and vaginal bleeding. For women with polycystic ovary syndrome and a body mass index greater than 30, letrozole should be considered as first-line therapy for ovulation induction because of the increased live birth rate compared with clomiphene citrate. Lifestyle changes that result in weight loss should be strongly encouraged. Aromatase inhibitors are a promising therapeutic option that may be helpful for the management of endometriosis-associated pain in combination therapy with progestins.