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Infertility: HELP
Articles by Joëlle Belaisch-Allart
Based on 19 articles published since 2008
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Between 2008 and 2019, J. Belaisch-Allart wrote the following 19 articles about Infertility.
 
+ Citations + Abstracts
1 Editorial [Is surrogacy a crime against humanity or a treatment for uterine infertility?]. 2015

Belaisch-Allart, J. ·Service de gynécologie obstétrique et médecine de la reproduction, centre hospitalier des 4 Villes, site de Sèvres, 141, Grande-Rue, 92318 Sèvres cedex, France. Electronic address: J.belaischallart@ch4v.fr. ·Gynecol Obstet Fertil · Pubmed #25596885.

ABSTRACT: -- No abstract --

2 Editorial ["Societal" assisted reproductive technology: why so scared?]. 2014

Belaisch-Allart, J. ·Service de gynécologie-obstétrique et de médecine de la reproduction, centre hospitalier des Quatre-Villes, site de Sèvres, 141, Grande-Rue, 92318 Sèvres cedex, France. Electronic address: j.belaischallart@ch4v.fr. ·Gynecol Obstet Fertil · Pubmed #25164161.

ABSTRACT: -- No abstract --

3 Review [Male age in assisted reproductive technologies: Is there a limit?] 2016

Belaisch-Allart, J / Ouazana, M / Bailly, M / Selva, J / Kulski, O / Boitrelle, F. ·Service de gynécologie obstétrique et médecine de la reproduction, centre hospitalier des 4-Villes, 92210 Saint-Cloud, France. Electronic address: j.belaischallart@ch4v.fr. · Laboratoire de biologie de la reproduction, CHI de Poissy-Saint-Germain-en-Laye, 78303 Poissy, France. · Service de gynécologie obstétrique et médecine de la reproduction, centre hospitalier des 4-Villes, 92210 Saint-Cloud, France. ·Gynecol Obstet Fertil · Pubmed #27839714.

ABSTRACT: In France, there does exist any age limit for infertile men management neither in the law nor for the coverage by the "French Assurance Maladie". French law specifies only that both partners of the couple have to be "of childbearing age", but there is no definition for men of childbearing age. Does legislation have to determine a limit on man management in function of his age? Could ART practitioners decide (themselves) whether they take care of infertile men or not? Should male age be a criteria to decide this management? Would ART practitioners "need" a legislation to help them to decide? In 2016, the "French Assurance Maladie" covers all costs for infertile couple if woman is less than 43 years old, whatever male age. If an age-threshold should be establish for the coverage of infertile men management by the "French Assurance Maladie", then what should be this threshold? In order to try to answer these questions, we asked them to French ART practitioners (gynecologists and embryologists) and gynecologists. The first questionnaire included 13 questions and was filled by 244 ART specialists; the second was filled by 138 gynecologists. Most of them agree to limit the male management and the coverage by the "French Assurance Maladie" at 60 for men in ART. Gynecologists who does not practice ART wish a limit for insurance (80% of them but are only 57% to wish a legal limit).

4 Review [Preservation of fertility in case of sterilizing treatment]. 2010

Bringer-Deutsch, S / Belaisch-Allart, J / Delvigne, A. ·Centre hospitalier des Quatre Villes, Service de gynécologie-obstétrique et médecine de la reproduction, Site de Sèvres, 141 Grande Rue, 92318 Sèvres, France. sbringer76@yahoo.fr ·J Gynecol Obstet Biol Reprod (Paris) · Pubmed #21185487.

ABSTRACT: The different options of fertility preservation must be approached with all patients before initiating any cancer therapy and physicians should refer each patient treated during their reproductive years to specialists in a specialized center that will evaluate the best available alternatives to preserve male and female fertility.The only efficiently proven ways of fertility preservation are sperm cryopreservation for men and embryo cryopreservation to preserve couple fertility. However, the recent progress observed with oocyte cryopreservation (in particular the oocyte vitrification) may change our practices in the future if vitrification is allowed in France. Although the law of Bioethics of 2004 authorizes the ovarian cryopreservation today, its modalities of use stay at present at the stage of the research. But in spite of the low number of published births today in France and in the world, the ovarian tissue cryopreservation is a promising technique. It remains the last possible alternative to protect fertility of prepubertal girls. The sperm cryopreservation must be systematically proposed to all men (even teenagers) undergoing a treatment for cancer potentially harmful for their fertility whatever their sperm quality. The testicular tissue cryopreservation is also a method to be discussed for adults, teenagers in case of failure of sperm banking or for prepubertal boys.

5 Review [Premature ovarian failure: which approaches?]. 2008

Belaisch-Allart, J / Mayenga, J-M / Grefenstete, I / Mokdad, A / Moumin, H. ·Service de gynécologie-obstétrique et médecine de la reproduction, centre hospitalier des Quatre-Villes, Site-de-Sèvres, 141, Grande-Rue, 92318 Sèvres cedex, France. jbelaisch@promptomail.com ·Gynecol Obstet Fertil · Pubmed #18657462.

ABSTRACT: Premature ovarian failure (POF) occurs in one case of 10,000 in women below the age of 20, one case of 1000 below 30 and 1% in women before the age of 40. In 80% of POF cases, the etiology is unknown, except for Turner syndrome. Spontaneous fertility is very weak, only 3 to 10% of the patients will have natural conception. If the diagnosis is confirmed, ovarian stimulation usually fails. When fertility is desired, the alternative treatments are oocyte and/or embryo donation or adoption and "learn to be happy just in couple". Psychological management is always necessary.

6 Article [Infertility over forty: Pros and cons of IVF]. 2015

Belaisch-Allart, J / Maget, V / Mayenga, J-M / Grefenstette, I / Chouraqui, A / Belaid, Y / Kulski, O. ·Centre hospitalier des 4 Villes, rue Lauer, 92210 Saint-Cloud, France. Electronic address: j.belaischallart@ch4v.fr. · Centre hospitalier des 4 Villes, rue Lauer, 92210 Saint-Cloud, France. ·Gynecol Obstet Fertil · Pubmed #26297163.

ABSTRACT: The population attempting pregnancy and having babies is ageing. The declining fertility potential and the late age of motherhood are increasing significantly the number of patients over forty consulting infertility specialists. Assisted reproductive technologies (ART) cannot compensate the natural decline in fertility with age. In France, in public hospital, ART is free of charge for women until 43 years, over 43, social insurance does not reimburse ART. Hence, 43 years is the usual limit, but between 40 and 42 is ART useful? The answer varies according to physicians, couples or society. On medical level, the etiology of the infertility must be taken into account. If there is an explanation to infertility (male or tubal infertility) ART is better than abstention. If the infertility is only due to age the question is raised. In France, the reimbursement by the society of a technique with very low results is discussed. However efficacy is not absolutely compulsory in Medicine. On the opposite to give false hopes may be discussed too. To obtain a reasonable consensus is rather difficult.

7 Article [Assisted reproductive technologies and ethics]. 2014

Belaisch-Allart, Joëlle. · ·Rev Prat · Pubmed #24649561.

ABSTRACT: Since the first birth after in vitro fertilization more than 5 million of IVF babies are born in the world. Assisted reproductive technologies captivate the public, they allow maternity without ovary (oocyte donation), without uterus (surrogate mother), paternity without spermatozoids (sperm donation), parentality without limits of age, parentality after death and homoparentality. These technologies arise a lot of ethics questions, the problem is that the answers are not the same all-round the world, laws are based on morals, beliefs, faiths, and convictions. Theses variations arise themselves questions on the value of these non-universal answers.

8 Article [Assisted reproductive technologies and ethics]. 2014

Belaisch-Allart, Joëlle. · ·Rev Prat · Pubmed #24649555.

ABSTRACT: -- No abstract --

9 Article [Social egg freezing: which problems?]. 2013

Belaisch-Allart, J / Brzakowski, M / Chouraqui, A / Grefenstette, I / Mayenga, J-M / Muller, E / Belaid, Y / Kulski, O. ·Service de gynécologie obstétrique et médecine de la reproduction, centre hospitalier des 4-Villes, site de Sèvres, 141, Grande-Rue, 92318 Sèvres cedex, France. j.belaischallart@ch4v.fr ·Gynecol Obstet Fertil · Pubmed #23972923.

ABSTRACT: In today's society, many women push pregnancy further away from the "right" childbearing age. Assisted reproduction, except egg donation, is unable to fully overcome the effect of age on fertility loss. The effectiveness of oocyte vitrification is demonstrated, and oocyte vitrification is allowed in the French Bioethics law of 2011. In the French law, oocyte' s cryopreservation is proposed to oocyte donors without child. Social egg freezing for non-medical reason is already legal in some countries, but leads to new debates and discussions.

10 Article [Endometrial preparation in oocyte recipients]. 2012

Grzegorczyk-Martin, V / Mayenga, J-M / Kulski, O / Belaid, Y / Grefenstette, I / Belaisch-Allart, J. ·Service de gynécologie obstétrique et médecine de la reproduction, centre hospitalier des Quatre-Villes, site de Sèvres, 141, grande Rue, 92318 Sèvres cedex, France. veronika_grey@yahoo.fr ·Gynecol Obstet Fertil · Pubmed #22906698.

ABSTRACT: Oocyte donation is offered to patients with premature ovarian failure to achieve pregnancy when no other assisted reproductive technology is possible. Some clinical and biological factors have been identified for influencing the outcome of oocyte donation cycles. Embryo implantation depends on embryo quality, method for the embryo transfer, and endometrial differentiation. In our center, the oocyte recipients receive for the endometrial preparatory cycle the same treatment that for the patients undergoing frozen embryos transfers, with good clinical pregnancy rates, about 35% per transfer. Estrogen and progesterone supplementation with GnRH agonist down regulation are used in synchronized protocols or for frozen embryos transfers. The synchronization between recipient's endometrium and donor's ovarian stimulation is very restrictive. Nowadays, the oocytes vitrification lithens the oocyte donation process: the endometrial preparation has a limited duration and is well controlled, and embryos that are transferred are all fresh embryos.

11 Article [How present ART' results: questions' list to French ART professionals and application on Amiens' ART results]. 2012

Cabry-Goubet, R / Boulard, V / Lourdel, E / Devaux, A / Copin, H / Belaisch-Allart, J / Merviel, P. ·Médecine et biologie de la reproduction, cytogénétique et CECOS de Picardie, CHU d'Amiens, maternité C.-Desmoulins, 124, rue C.-Desmoulins, 80000 Amiens, France. cabry.rosalie@chu-amiens.fr ·Gynecol Obstet Fertil · Pubmed #21903441.

ABSTRACT: OBJECTIVES: ART transparency of results and ways to submit are in centre of present biologists and clinical cares. This work aims at identifying ART results' presentation pertinent tests. PATIENTS AND METHODS: At first time, we propose a questions' list to French ART professionals. Next, we apply results on Amiens' ART center 2006, 2007 and 2008 IVF parameters. RESULTS: One hundred and twenty questions' lists were analysed. Ninety percent of interrogated people were in favour of the results' center public communication. Most quoting criterions hold to define a reference population are (percentage of favourable opinions): IVF/ICSI treatment (96%), first of second rank's attempts (71%), women age less than 35 years old (68%), one or two top embryos quality transfer (60%). In 2007, 2008 and 2009, we made 1123 tentative IVF±ICSI in Amiens' ART center. Pregnancy rates were analysed for these years with criterions next quoting as most pertinent (women's age and rank's attempt), and in function of puncture retrieval oocytes number and indications. DISCUSSION AND CONCLUSION: Most of professionals are in favour of ART transparency of results. All would like that results presentation holds to special criterions to allow a fair comparison. Pregnancy predictive factors, which are women age, rank attempt, puncture retrieval oocytes number, seem to be main criterions for evaluation. These criterions pertinence has been shown thanks to Amiens ART center results.

12 Article [The place of ovarian drilling in the management of polycystic ovarian syndrome (PCOS)]. 2011

Mayenga, J-M / Grzegorczyk Martin, V / Belaisch-Allart, J. ·Service de gynécologie obstétrique et médecine de la reproduction, centre hospitalier des 4 Villes-Site de Sèvres, 141 Grande-Rue, Sèvres cedex, France. jm.mayenga@ch4v.fr ·Gynecol Obstet Fertil · Pubmed #21840744.

ABSTRACT: The surgical approach has been a long-lasting option for ovulation restoration in patients presenting with polycystic ovarian syndrome. It consists of ovarian drilling with monopolar, bipolar energy or laser through laparoscopic or vaginal hydrolaparoscopic route. It is intended to be used as a second line therapy as an alternative to gonadotropins in patients with resistance or failure after clomiphene citrate. The results in terms of ovulation restoration and live births make it an attractive alternative with less complications such as multiple pregnancies and ovarian hyperstimulation syndrome.

13 Article [Prognosis criteria for the management of the infertile couple]. 2010

Dechanet, C / Belaisch-Allart, J / Hédon, B. ·Hôpital Arnaud de Villeneuve, Département de médecine de la reproduction, 371 avenue du Doyen Gaston Giraud, 34295 Montpellier cedex, France. clodechanet@gmail.com ·J Gynecol Obstet Biol Reprod (Paris) · Pubmed #21185491.

ABSTRACT: Advanced maternal age, obesity and cigarette smoking are associated with decreased fertility, adverse Assisted Reproductive Technologies (ART) outcomes and fetal and neonatal complications. IVF failures increase dramatically in women aged between 42-43 years. Advanced paternal age is associated with fetal and neonatal adverse outcomes. However, it remains uncertain that advanced paternal age could impair IVF results. Obesity (Body mass index more than 30 kg/m(2)) is associated with lower fecundity, pregnancy complications and adverse ART results. The rate of complications is increasing with higher BMI. Cigarette smoking is associated with longer time to conceive and decreased IVF results. In case of infertility associated with obesity or cigarette smoking, physicians have to inform their patient about the benefits of smoking cessation and weight loss. However, maternal age had to be considered as the main prognosis factor before delaying ART because of dietary or smoking cessation program.

14 Article [Assisted reproductive technologies place]. 2010

Amar-Hoffet, A / Hédon, B / Belaisch-Allart, J. ·Hôpital Saint Joseph, Unité de médecine de la reproduction, 26 bd de Louvain, 13008 Marseille, France. ·J Gynecol Obstet Biol Reprod (Paris) · Pubmed #21185490.

ABSTRACT: There are three kinds of infertility treatment: medical treatment, surgical treatment and assisted reproductive technology (ART). ART includes intra uterine insemination (IUI), in vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI). ART technologies made a lot of progress last years and their field of applications extended. Through literature reviews, IUI is recommended for unexplained infertility and discussed for male or cervical infertility. IVF is recommended for tubal and unexplained infertility. Limits between IVF and ICSI in case of male infertility remains unclear. In non mal infertility ICSI is not recommended.

15 Article [Infertility treatments after gynecologic cancers and indications of ovarian tissue cryopreservation]. 2010

Belaisch-Allart, Joëlle / Bringer-Deutch, Sophie. ·Gynécologie Obstétrique et Médecine de la Reproduction, Centre Hospitalier des 4 Villes, 141 grande Rue, 92318 Sèvres cedex. j.belaischallart@ch4v.fr ·Bull Acad Natl Med · Pubmed #21171244.

ABSTRACT: Increasing numbers of young people are surviving cancer, but treatment can affect their reproductive function. Female fertility is more difficult to preserve than male fertility. Fertility-sparing treatments may be possible for some women. For others, embryo cryopreservation is the only established option, provided cancer therapy can be postponed. However, cryopreservation of eggs or ovarian tissue is now becoming a real possibility. Medically assisted reproductive options for cancers survivors include ovarian stimulation, IVF and oocyte donation. Gestational surrogacy and adoption are other possibilities.

16 Article [In Vitro Fertilization: beware of oocyte retrieval without oocyte!]. 2010

Bringer-Deutsch, S / Mayenga, J-M / Grefenstette, I / Grzegorczyk, V / Kulski, O / Belaisch-Allart, J. ·Service de gynécologie obstétrique et médecine de la reproduction, centre hospitalier des 4-Villes, site de Sèvres, 141, grande-rue, 92318 Sèvres cedex, France. sbringer76@yahoo.fr ·Gynecol Obstet Fertil · Pubmed #21115382.

ABSTRACT: A 30-year-old woman undergoing an In Vitro Fertilization (IVF) treatment for tubal infertility and for whom no oocyte was retrieved at the puncture ("white puncture") presented an ectopic pregnancy. The patient was asymptomatic except some bleeding events reported for several days prior to the puncture. The ovulation monitoring was normal throughout the stimulation by gonadotrophin and hCG was administered for the final oocyte maturation on the twelfth day of stimulation at a rate of 2771 pg/ml of estradiol with a perfect ultrasound follicular growth. This case demonstrates that we have to beware of a "white puncture" and that the hCG measurement the day of the oocyte retrieval is necessary because of the possibility of an ectopic pregnancy.

17 Article [Treatment options for age-related infertility]. 2010

Belaisch-Allart, Joëlle. ·Service de gynécologie obstétrique et médecine de la reproduction, Centre hospitalier des Quatre Villes, site de Sèvres, 92318 Sèvres Cedex. jbelaisch@promptomail.com ·Rev Prat · Pubmed #20623902.

ABSTRACT: There has been a consistent trend towards delayed childbearing in most Western countries. Treatment options for age-related infertility includes controlled ovarian hyperstimulation with intrauterine insemination and in vitro fertilization (IVF). A sharp decline in pregnancy rate with advancing female age is noted with assisted reproductive technologies (ART) including IVF. Evaluation and treatment of infertility should not be delayed in women 35 years and older. No treatment other than oocyte donation has been shown to be effective for women over 40 and for those with compromised ovarian reserve, but its pratice is not easy in France hence the procreative tourism. As an increasing number of couples choose to postpone childbearing, they should be informed that maternal age is an important risk factor for failure to conceive.

18 Article [Predictive factors of success in ovulation induction with recombinant FSH: results of Indigo study]. 2010

Cédrin-Durnerin, I / Belaisch-Allart, J / Avril, C / Pouly, J-L. ·Service de médecine de la reproduction, hôpital Jean-Verdier, avenue du 14-Juillet, 93143 Bondy cedex, France. isabelle.cedrin-durnerin@jvr.aphp.fr ·Gynecol Obstet Fertil · Pubmed #20106707.

ABSTRACT: INTRODUCTION: Although ovulation induction is commonly used to treat infertility, few data are available concerning this treatment. Therefore, the aim of this prospective observational study was to describe medical practices and to identify predictive outcome factors of ovarian stimulation by recombinant FSH (r-hFSH), administrated with a self-injector pen. PATIENTS AND METHODS: At the time of the prescription of ovarian stimulation followed by sexual intercourse (SI) or artificial insemination (HAI) with a normal husband sperm, 370 gynaecologists consecutively sent from January to November 2005, for a maximum of six patients (1398 patients in total), a form dealing with the assessment of infertility factors prior to stimulation (n=1340), then a monitoring form of the treated cycle (n=1227) and when a pregnancy was obtained, a follow-up form at 12 weeks of amenorrhea (n=254). Each patient had to complete an autoquestionnaire about the use of the pen (n=1044). RESULTS: Seventy percent of the contributing gynaecologists had only a private practice. The mean age of patients was 31.9+/-4.8 years. Dealing with infertility exploration prior to stimulation, 9% did not have tubal assessment. Although it was the first stimulation attempt for 52% of cases, 91% of patients found the pen easy to manipulate. The mean duration of r-hFSH administration was 8.8+/-3.7 days and the mean daily dose was 75.4+/-29.4 IU. Ultrasound and hormonal monitoring was performed for 88% of patients. The cycle cancellation rate was 11%. The hCG administration was performed on cycle day 13+/-3. An HAI was programmed in 60% of patients and SI in 40%. The pregnancy rates for positive betahCG, ongoing and multiple pregnancies were, respectively, 22.7, 18 and 16% (twins 14%; 2% of triplets or more 2%). Three prognosis factors were independently related to ongoing pregnancy rate: age<35 years, previous pregnancy obtained by treatment and presence of ovulatory disorders. DISCUSSION AND CONCLUSION: This observatory of ovarian stimulation out of FIV allowed to describe medical practices of gynaecologists: infertility assessment prior to ovarian stimulation, used FSH doses, ultrasound and hormonal monitoring, and it outlined three predictive factors of outcome: age, previous pregnancy obtained by treatment and presence of ovulatory disorders.

19 Article [A study comparing previous induced abortion rates in populations of newly delivered women and infertile women]. 2008

Hamy, A-S / Mayenga, J-M / Grefenstette, I / Kerneis, S / Belaisch-Allart, J. ·Service de gynécologie-obstétrique et de reproduction humaine, chirurgie et assistance médicale à la procréation, CHI Jean-Rostand, 141, Grande-Rue, 92 318 Sèvres cedex, France. ·Gynecol Obstet Fertil · Pubmed #18400548.

ABSTRACT: OBJECTIVE: For years, induced abortions (IA) have been deemed responsible for altered fertility. The implication of various mechanisms including tubal infertility, intra-uterine adhesions, spontaneous abortion, ectopic pregnancy, cervical incompetence, shortened gestations, and any psychological trouble leading to anovulation has been raised. Though many authors find no evidence of an increased risk on fertility for women, whose IA is not complicated by infection, it might sometimes be insinuated that infertility is the consequence of previous abortion. Thus, we compared the rate of patients with any prior IA in a population of newly delivered women and in women ongoing IVF. PATIENTS AND METHODS: A retrospective study was conducted at Sèvres hospital, comparing two populations of women, newly delivered women (n=1738) between January 1st and December 31st 2005, and women ongoing IVF at the same period (n=430). We reported the number of previous medical or surgical induced abortions and compared it in both groups. Another analysis compared these rates, among two subgroups of women with one or more prior pregnancy (secondary infertility (n=148), and secondary gestation (n=1088). RESULTS: The rate of prior IA was not different in the two populations. In the IVF group, 13% (n=56) had undergone one or more IA, versus 16.7% (n=291) in the newly delivered group (P=0.06). Among women with previous pregnancy, 37.8% (56) women of the IVF group had undergone one or more previous IA, versus 26.7% (291) of the newly delivered women (P=0.007). DISCUSSION AND CONCLUSION: As expected by literature data on IA and fertility, rates of prior induced abortions were not different in the population of fertile women versus infertile. However, women with one or more previous pregnancy are more likely to have undergone previous IA in the IVF group than in the newly delivered group, possibly due to a bias of age. More data are requested to eliminate linkage between IA and infertility.