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Infertility: HELP
Articles by Tristan Gauthier
Based on 10 articles published since 2008
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Between 2008 and 2019, T. Gauthier wrote the following 10 articles about Infertility.
 
+ Citations + Abstracts
1 Guideline [Management of endometriosis: CNGOF-HAS practice guidelines (short version)]. 2018

Collinet, P / Fritel, X / Revel-Delhom, C / Ballester, M / Bolze, P A / Borghese, B / Bornsztein, N / Boujenah, J / Bourdel, N / Brillac, T / Chabbert-Buffet, N / Chauffour, C / Clary, N / Cohen, J / Decanter, C / Denouël, A / Dubernard, G / Fauconnier, A / Fernandez, H / Gauthier, T / Golfier, F / Huchon, C / Legendre, G / Loriau, J / Mathieu-d'Argent, E / Merlot, B / Niro, J / Panel, P / Paparel, P / Philip, C A / Ploteau, S / Poncelet, C / Rabischong, B / Roman, H / Rubod, C / Santulli, P / Sauvan, M / Thomassin-Naggara, I / Torre, A / Wattier, J M / Yazbeck, C / Canis, M. ·Clinique de gynécologie, hôpital Jeanne-de-Flandre, CHRU de Lille, 59000 Lille, France; Université Lille-Nord-de-France, 59000 Lille, France. Electronic address: pierre.collinet@chru-lille.fr. · Service de gynécologie-obstétrique et médecine de la reproduction, Inserm CIC 1402, 2, rue de la Milétrie, 86000 Poitiers, France; Université de Poitiers, 86000 Poitiers, France; Inserm CIC 1402, 86000 Poitiers, France. · Haute Autorité de santé, 5, avenue du Stade-de-France, 93218 La Plaine-Saint-Denis cedex, France. · Service de gynécologie-obstétrique et médecine de la reproduction, CHU Tenon, AP-HP, 4, rue de la Chine, 75020 Paris, France. · Service de chirurgie gynécologique oncologique, obstétrique, CHU Lyon-Sud, 165, chemin du Grand-Revoyet, 69495 Pierre-Bénite, France; Université Claude-Bernard-Lyon 1, 69000 Lyon, France. · Service de chirurgie gynécologie-obstétrique 2 et médecine de la reproduction, CHU Cochin, AP-HP, 27, rue du Faubourg-Saint-Jacques, 75014 Paris, France; Équipe génomique, épigénétique et physiopathologie de la reproduction, département développement, reproduction, cancer, Inserm U1016, université Paris Descartes, Sorbonne Paris Cité, 12, rue de l'École-de-Médecine, 75270 Paris cedex 06, France. · 29, rue de l'Essonne, 91000 Evry, France. · Service de gynécologie-obstétrique, CHU Bondy, avenue du 14-Juillet, 93140 Bondy, France; Centre médical du Château, 22, rue Louis-Besquel, 94300 Vincennes, France. · Service de gynécologie-obstétrique et reproduction humaine, CHU Estaing, 1, place Lucie-Aubrac, 63003 Clermont-Ferrand, France; Faculté de médecine, Encov-ISIT, UMR6284 CNRS, université d'Auvergne, 28, place Henri-Dunant, 63000 Clermont-Ferrand, France. · 98, route de Blagnac, 31200 Toulouse, France. · Service de gynécologie-obstétrique et médecine de la reproduction, CHU Tenon, AP-HP, 4, rue de la Chine, 75020 Paris, France; GRC-6 centre expert en endométriose (C3E), Sorbonne université, Paris, France; UMR-S938 Inserm Sorbonne université, Paris, France. · Service de gynécologie-obstétrique et reproduction humaine, CHU Estaing, 1, place Lucie-Aubrac, 63003 Clermont-Ferrand, France. · 3, rue Pablo-Picasso, 92160 Antony, France. · Service d'assistance médicale à la procréation et de préservation de la fertilité, hôpital Jeanne-de-Flandre, CHRU de Lille, 1, rue Eugène-Avinée, 59037 Lille cedex, France; EA 4308 gamétogenèse et qualité du gamète, CHRU de Lille, 59037 Lille cedex, France. · EndoFrance, BP 50053, 01124 Montluel cedex, France. · Université Claude-Bernard-Lyon 1, 69000 Lyon, France; Clinique gynécologique et obstétricale, hôpital de la Croix-Rousse, groupe hospitalier Nord, CHU de Lyon-HCL, 103, grande rue de la Croix-Rousse, 69317 Lyon cedex, France. · Service de gynécologie-obstétrique, CHI Poissy-St-Germain, 10, rue du Champ-Gaillard, 78303 Poissy, France; EA 7285 risques cliniques et sécurité en santé des femmes, université Versailles-Saint-Quentin-en-Yvelines, Saint-Quentin-en-Yvelines, France. · Service de gynécologie-obstétrique, CHU Bicêtre, AP-HP, 78, avenue du Général-de-Gaulle, 94275 Le Kremlin-Bicêtre, France; CESP-INSERM, U1018, équipe épidémiologie et évaluation des stratégies de prise en charge, VIH, reproduction, pédiatrie, université Paris-Sud, Paris, France. · Service de gynécologie-obstétrique, hôpital Mère-Enfant, CHU de Limoges, 8, avenue Dominique-Larrey, 87042 Limoges, France; UMR-1248, faculté de médecine, 87042 Limoges, France. · Service de chirurgie gynécologique oncologique, obstétrique, CHU Lyon-Sud, 165, chemin du Grand-Revoyet, 69495 Pierre-Bénite, France. · Service de gynécologie-obstétrique, CHI Poissy-St-Germain, 10, rue du Champ-Gaillard, 78303 Poissy, France. · Service de gynécologie-obstétrique, CHU d'Angers, 4, rue Larrey, 49033 Angers cedex 01, France; CESP-Inserm, U1018, équipe 7, genre, santé sexuelle et reproductive, université Paris-Sud, 94276 Le Kremlin-Bicêtre cedex, France. · Service de chirurgie digestive, groupe hospitalier Paris Saint-Joseph, 185, rue Raymond-Losserand, 75001 Paris, France. · Service de gynécologie-obstétrique et médecine de la reproduction, CHU Tenon, AP-HP, 4, rue de la Chine, 75020 Paris, France; Université Pierre-et-Marie-Curie Paris 6, Paris, France; GRC6-UPMC, centre expert en endométriose (C3E), hôpital Tenon, Paris, France. · Service de chirurgie gynécologique, clinique Tivoli, 220, rue Mandron, 33000 Bordeaux, France. · Service de gynécologie-obstétrique, centre hospitalier de Versailles, 177, route de Versailles, 78157 Le Chesnay cedex, France. · Service d'urologie, CHU Lyon-Sud, 165, chemin du Grand-Revoyet, 60495 Pierre-Bénite, France. · Service de gynécologie-obstétrique et médecine de la reproduction, hôpital Mère-Enfant, CHU de Nantes, 8, boulevard Jean-Monnet, 44093 Nantes, France. · Service de gynécologie-obstétrique, centre hospitalier Renée-Dubos, 6, avenue de l'Île-de-France, 95300 Pontoise, France; Université Paris 13, Sorbonne Paris Cité, UFR SMBH, 93022 Bobigny, France. · Centre expert de diagnostic et prise en charge multidisciplinaire de l'endométriose, clinique gynécologique et obstétricale, CHU Charles-Nicolle, 1, rue de Germont, 76031 Rouen, France. · Clinique de gynécologie, hôpital Jeanne-de-Flandre, CHRU de Lille, 59000 Lille, France; Université Lille-Nord-de-France, 59000 Lille, France. · Service de gynécologie-obstétrique, CHU Bicêtre, AP-HP, 78, avenue du Général-de-Gaulle, 94275 Le Kremlin-Bicêtre, France. · Service d'imagerie, hôpital Tenon, AP-HP, 4, rue de la Chine, 75020 Paris, France; Sorbonne universités, UPMC université Paris 06, Paris, France; Institut universitaire de cancérologie, Assistance publique, Paris, France. · Service de gynécologie-obstétrique et médecine de la reproduction, hôpital Arnaud-de-Villeneuve, CHU de Montpellier, 371, avenue du Doyen-Gaston-Giraud, 34295 Montpellier, France. · Centre d'étude et traitement de la douleur, hôpital Claude-Huriez, CHRU de Lille, rue Michel-Polonowski, 59000 Lille, France. · Service de gynécologie-obstétrique, hôpital Foch, AP-HP, 40, rue Worth, 92151 Suresnes, France; Centre d'assistance médicale à la procréation, clinique Pierre-Cherest, 5, rue Pierre-Cherest, 92200 Neuilly-Sur-Seine, France. ·Gynecol Obstet Fertil Senol · Pubmed #29550339.

ABSTRACT: First-line investigations to diagnose endometriosis are clinical examination and pelvic ultrasound. Second-line investigations include pelvic examination performed by a referent clinician, transvaginal ultrasound performed by a referent echographist, and pelvic MRI. It is recommended to treat endometriosis when it is symptomatic. First-line hormonal treatments recommended for the management of painful endometriosis are combined with hormonal contraceptives or levonorgestrel 52mg IUD. There is no evidence to recommend systematic preoperative hormonal therapy for the unique purpose of preventing the risk of surgical complications or facilitating surgery. After endometriosis surgery, combined hormonal contraceptives or levonorgestrel SIU 52mg are recommended as first-line therapy in the absence of desire of pregnancy. In case of initial treatment failure, recurrence, or multiple organ involvement by endometriosis, medico-surgical and multidisciplinary discussion is recommended. The laparoscopic approach is recommended for the surgical treatment of endometriosis. HRT may be offered in postmenopausal women operated for endometriosis. In case of infertility related to endometriosis, it is not recommended to prescribe anti-gonadotropic hormone therapy to increase the rate of spontaneous pregnancy, including postoperatively. The possibilities of fertility preservation should be discussed with the patient in case of surgery for ovarian endometrioma.

2 Editorial [Should we change our indications for ovarian tissue cryopreservation?]. 2009

Aubard, Y / Piver, P / Gauthier, T. ·Service de gynécologie obstétrique, hôpital Mère-Enfant, CHU de Limoges, 6, avenue Dominique-Larrey, 87000 Limoges, France. yves.aubard@unilim.fr ·Gynecol Obstet Fertil · Pubmed #19782629.

ABSTRACT: -- No abstract --

3 Review Organizing a uterus transplantation programme: The designation of Uterus Transplantation Centres in France. 2019

Lavoué, Vincent / Dion, Ludivine / Tardieu, Antoine / Garbin, Olivier / Ayoubi, Jean Marc / Agostini, Aubert / Collinet, Pierre / Piver, Pascal / Aubard, Yves / Gauthier, Tristan / Anonymous1431128. ·Service de Gynécologie, CHU de Rennes, Hôpital Sud, 16, boulevard de Bulgarie, 35000 Rennes, France. Electronic address: Vincent.lavoue@chu-rennes.fr. · Service de Gynécologie, CHU de Rennes, Hôpital Sud, 16, boulevard de Bulgarie, 35000 Rennes, France. · Département de Gynécologie Obstétrique, CHU Limoges, avenue Dominique-Larrey, 87000 Limoges, France; INSERM, UMR-s850, CHU Limoges, 87000 Limoges, France. · Département de Gynécologie, Pôle de Gynécologie Obstétrique des Hôpitaux Universitaire de Strasbourg, Site du CMCO, 67091 Strasbourg, France. · Département de Gynécologie, Hôpital Foch, 92150 Suresnes, France. · Département de Gynécologie Obstétrique - Gynécologie, CHU de Marseille - Hôpital de la Conception, 13385 Marseille, France. · Clinique Gynécologique, Hôpital Jeanne-de-Flandre, CHRU Lille, 59037 Lille cedex, France. ·J Gynecol Obstet Hum Reprod · Pubmed #30266272.

ABSTRACT: Absolute uterine factor infertility affects several thousand young women in France. The first healthy child delivered to a uterus transplant recipient took place in 2014, and uterus transplantation is developing rapidly in many countries. The French College of Gynaecologists and Obstetricians (CNGOF) formed a uterus transplantation committee (CETUF) in 2015 to advance this technology in France. The CETUF sets out the criteria for the designation of Uterus Transplantation Centres. The objectives, requirements, operation and responsibilities of these centres have been described. Their responsibilities for organizing geographical coverage, continuity of care, communication, training, research and evaluation have been defined. This document will serve as a guide for the authorities concerned, to ensure that the means are provided to adequately manage patients with absolute uterine factor infertility who require uterus transplantation.

4 Review Which Donor for Uterus Transplants: Brain-Dead Donor or Living Donor? A Systematic Review. 2017

Lavoué, Vincent / Vigneau, Cécile / Duros, Solène / Boudjema, Karim / Levêque, Jean / Piver, Pascal / Aubard, Yves / Gauthier, Tristan. ·1 Department of Gynecology, Rennes University Hospital, Rennes, France. 2 Faculty of Medicine, University of Rennes 1, Rennes, France. 3 ER 440, OSS, CRLCC Eugène Marquis, Rennes, France. 4 Department of Nephrology, Hôpital Pontchaillou, Rennes University Hospital, Rennes, France. 5 Institute for Environmental, Health and Labor Research (IRSET), Rennes, France. 6 Rennes University Hospital, Department of Liver Surgery, Hôpital Pontchaillou, Rennes, France. 7 Department of Gynecology and Obstetrics, Hôpital Mère-Enfant, CHU Dupuytren, Limoges, France. 8 Pharmacology, Toxicology and Drug Safety Monitoring, INSERM, Limoges, France. ·Transplantation · Pubmed #27607535.

ABSTRACT: BACKGROUND: The aim of this systematic review was to evaluate and compare the pros and cons of using living donors or brain-dead donors in uterus transplantation programs, 2 years after the first worldwide live birth after uterus transplantation. METHODS: The Medline database and the Central Cochrane Library were used to locate uterine transplantation studies carried out in human or nonhuman primates. All types of articles (case reports, original studies, meta-analyses, reviews) in English or French were considered for inclusion. RESULTS: Overall, 92 articles were screened and 44 were retained for review. Proof of concept for human uterine transplantation was demonstrated in 2014 with a living donor. Compared with a brain-dead donor strategy, a living donor strategy offers greater possibilities for planning surgery and also decreases cold ischemia time, potentially translating into a higher success rate. However, this approach poses ethical problems, given that the donor is exposed to surgery risks but does not derive any direct benefit. A brain-dead donor strategy is more acceptable from an ethical viewpoint, but its feasibility is currently unproven, potentially owing to a lack of compatible donors, and is associated with a longer cold ischemia time and a potentially higher rejection rate. CONCLUSIONS: The systematic review demonstrates that uterine transplantation is a major surgical innovation for the treatment of absolute uterine factor infertility. Living and brain-dead donor strategies are not mutually exclusive and, in view of the current scarcity of uterine grafts and the anticipated future rise in demand, both will probably be necessary.

5 Review [Uterine transplantation: animal and human studies]. 2008

Gauthier, T / Hardeman, S / Piver, P / Aubard, Y. ·Service de gynécologie-obstétrique, hôpital de la Mère et de l'Enfant, CHU de Limoges, 8, avenue Dominique-Larrey, 87000 Limoges, France. gauthiertristan@yahoo.fr ·Gynecol Obstet Fertil · Pubmed #19026586.

ABSTRACT: Many cases of not life saving transplanted organs were described with the aim of improving quality of life. Uterus graft could be an alternative solution to adoption or surrogacy for women who have uterine factor infertility. Different animals' studies with mouse, sheep or monkey showed feasibility of the surgical technique with large vessels patch. One case of human uterine transplant has been reported but failed. Cold storage of the uterus in protective solution has been explored with mouse, sheep and human. Only pregnancy after uterus graft by syngenic mouse has been published. Results about pregnancy after allograft with sheep or monkey are necessary before pregnancy after human uterus graft becomes a reality.

6 Article Uterus transplantation in France: for which patients? 2016

Huet, S / Tardieu, A / Filloux, M / Essig, M / Pichon, N / Therme, J F / Piver, P / Aubard, Y / Ayoubi, J M / Garbin, O / Collinet, P / Agostini, A / Lavoue, V / Piccardo, A / Gauthier, T. ·Department of Obstetrics-Gynecology, Hôpital Mère-Enfant, CHU Limoges, av Dominique Larrey, 87000 Limoges, France. · Department of Immunology, CHU Limoges, 87000 Limoges, France. · Department of Nephrology, Hemodialysis, Transplantation, CHU Limoges, 87000 Limoges, France; Department of Pharmacology, Toxicology and Pharmacovigilance, Inserm, UMR-s850, CHU Limoges, 87000 Limoges, France. · Hospital Organ Retrieval Network, CHU Limoges, 87000 Limoges, France. · Department of Psychiatry, CH Esquirol, 87000 Limoges, France. · Department of Obstetrics-Gynecology, Hôpital Mère-Enfant, CHU Limoges, av Dominique Larrey, 87000 Limoges, France; Department of Pharmacology, Toxicology and Pharmacovigilance, Inserm, UMR-s850, CHU Limoges, 87000 Limoges, France. · Department of Gynecology, Foch Hospital, 92150 Suresnes, France. · Department of Gynecology, pôle de gynécologie obstétrique des Hôpitaux universitaires de Strasbourg, site du cmco, 67091 Strasbourg, France. · Gynecology Clinic, Hôpital Jeanne de Flandre, CHRU Lille, 59037 Lille cedex, France. · Department of Gynecology Obstetric - Gynécologie CHU de Marseille - Hôpital de la Conception, 13385 Marseille, France. · Department of Gynecology, CHU de Rennes, 35000 Rennes, France; Université de Rennes 1, France. · Department of Vascular Surgery and Transplantation, CHU Limoges, 87000 Limoges, France. · Department of Obstetrics-Gynecology, Hôpital Mère-Enfant, CHU Limoges, av Dominique Larrey, 87000 Limoges, France; Department of Pharmacology, Toxicology and Pharmacovigilance, Inserm, UMR-s850, CHU Limoges, 87000 Limoges, France. Electronic address: tristan.gauthier@chu-limoges.fr. ·Eur J Obstet Gynecol Reprod Biol · Pubmed #27552172.

ABSTRACT: OBJECTIVE: Uterine infertility (UI), which can be caused by a variety of congenital or acquired factors, affects several thousand women in Europe. Uterus transplantation (UTx), at the current stage of research, offers hope for these women to be both the biological mother and the carrier of their child. However, the indications of UTx still need to be defined. The main aim of the study was to describe the different etiologies of UI and other data as marital and parental status from women requesting UTx who contacted us in the framework of a UTx clinical trial. Secondarily, we discussed the potential indications of UTx and their feasibility. STUDY DESIGN: This is an observational study. RESULTS: Of a total of 139 patients with UI, 105 patients (75.5%) had uterine agenesis, making it the leading cause of UI in this sample. Among the patients with uterine agenesis, 25% had a solitary kidney and 44.7% had undergone vaginal reconstruction. Peripartum hysterectomy, hysterectomy for cancer, and hysterectomy for benign pathologies accounted for 9.4%, 7.2% and 5% of cases, respectively. Less common causes of UI included complete androgen insensitivity syndrome (2.2% of patients) and prenatal diethylstilbestrol exposure (0.7%). Approximately 14% of the women already had at least one child and 66% were in a couple living together for at least 2 years. CONCLUSION: UTx is still under evaluation and further research is under way. Nulliparous patients with no major medical or surgical history and with normal ovarian function, who meet the legal criteria for medically assisted reproduction, represent the best indications for UTx at this stage of its development.

7 Article [Uterine transplantation: is there a real demand?]. 2015

Gauthier, T / Garnault, D / Therme, J-F / Piver, P / Essig, M / Pichon, N / Marquet, P / Aubard, Y. ·Service de gynécologie-obstétrique, hôpital Mère-Enfant, CHU de Limoges, avenue Larrey, 87000 Limoges, France; Pharmacologie, toxicologie et pharmacovigilance, Inserm, UMR-S850, CHU de Limoges, 87000 Limoges, France. Electronic address: tristan.gauthier@chu-limoges.fr. · Centre de recherches psychanalyse, médecine et sociétés (CRPMS EA 3522), université Paris Diderot, 75013 Paris, France. · Consultations de psychiatrie, CHU de Limoges, 87000 Limoges, France. · Service de gynécologie-obstétrique, hôpital Mère-Enfant, CHU de Limoges, avenue Larrey, 87000 Limoges, France. · Coordination hospitalière des prélèvements, CHU de Limoges, 87000 Limoges, France. · Service néphrologie, dialyse et transplantation, CHU de Limoges, 87000 Limoges, France. · Pharmacologie, toxicologie et pharmacovigilance, Inserm, UMR-S850, CHU de Limoges, 87000 Limoges, France. ·Gynecol Obstet Fertil · Pubmed #25595943.

ABSTRACT: OBJECTIVES: To study the demand there is for uterus transplantation (UTx). PATIENTS AND METHODS: Recent media coverage of developments in UTx prompted associations of patients with Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome and of women suffering from UI to contact us. We sent them anonymous questionnaires devised to sound out their attitude towards UTx and towards adoption and gestational surrogacy (GS). A clinical psychologist also carried out a qualitative discourse analysis. RESULTS: Sixty patients answered the questionnaire. Thirty-eight patients were married or living with a male partner. Seven patients had had a hysterectomy. Fifty-one patients had uterine agenesis. Of the 60 patients, 19 and 21, respectively, had ruled out the option of adoption or GS, and 11 would not envisage either possibility. Thirty-five patients were willing to take part in a clinical study into UTx despite the uncertainty of the outcome and the potential risks involved. Of these 35 volunteers, 23 were in a heterosexual relationship and aged ≤35 years. DISCUSSION AND CONCLUSION: For women with UI the condition is all the more distressing because there is no medical solution for it. UTx could hold out hope for some of these patients despite the complexity of the procedure and the attendant risks. Because of the feelings of vulnerability engendered by UI, any UTx programme should provide full information to patients and ensure they are carefully screened and selected.

8 Article [Uterus transplantation. Current situation]. 2012

Gauthier, T / Piver, P / Mesnard, C / Marquet, P / Pichon, N / Guillaudeau, A / Drouet, M / Gardet, E / Laskar, M / Essig, M / Aubard, Y. ·Service de gynécologie-obstétrique, hôpital Mère-Enfant, CHU Dupuytren, avenue Larrey, 87000 Limoges, France. tristan.gauthier@chu-limoges.fr ·Gynecol Obstet Fertil · Pubmed #23084737.

ABSTRACT: Except adoption, absolute uterine factor infertility lacks solution in case of motherhood desire. Gestational surrogacy is still not approved in France. Over the last decade, uterus transplantation experimentation made advances. Data from animal research, progress in immunosuppressive treatment and knowledge about pregnancy after transplantation provide a scenario in which a human allotransplantation project can become reality.

9 Article Conservative treatment of big yolk sac tumour of the ovary in young girl. 2010

Beurdeley, M / Gauthier, T / Piguet, C / Fourcade, L. ·Service de Chirurgie Pédiatrique, Hôpital Mère-Enfant, CHU Dupuytren, 87000 Limoges, France. ·J Visc Surg · Pubmed #20920902.

ABSTRACT: We present the case of a large yolk sac tumour of the ovary in a 14-year-old girl with high level of serum alpha-feto-protein (AFP). Multidisciplinary care is important to do appropriate surgical treatment with the aim of fertility preservation.

10 Article [Chemotherapy and women fertility preservation]. 2010

Gauthier, Tristan / Piver, Pascal / Durand, Lise-Marie / Donadel, Lorène / Pech, Jean-Christophe / Roux, Christophe / Aubard, Yves. ·CHU Dupuytren, hôpital Mère-Enfant, service gynécologie-obstétrique, avenue Dominique-Larrey, 87000 Limoges, France. gauthiertristan@yahoo.fr ·Presse Med · Pubmed #20472381.

ABSTRACT: Agressive chemotherapy can lead to premature ovarian failure and loss of fertility in women and children. Embryo cryopreservation is an established clinical procedure of fertility preservation but with several limitations. Others options are available. Cryopreservation ovarian cortex tissu have to be suggested in case of high gonadotoxic treatment. It doesn't require puberty and delay in initiation of chemotherapy. The first birth in France after orthotopic graft of ovarian tissu thawed have been recently described with a promising process. Oocyte cryopreservation is available for women without partner but the experience is limited. Gonadotrophin-releasing hormone (GnRH) agonist therapy as ovarian protectants seem interesting. Follicular growth and maturation in vitro are still experimental.