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Sleep Initiation and Maintenance Disorders: HELP
Articles by Hreinn Stefansson
Based on 1 article published since 2008
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Between 2008 and 2019, Hreinn Stefansson wrote the following article about Sleep Initiation and Maintenance Disorders.
 
+ Citations + Abstracts
1 Article Genome-wide association analysis of insomnia complaints identifies risk genes and genetic overlap with psychiatric and metabolic traits. 2017

Hammerschlag, Anke R / Stringer, Sven / de Leeuw, Christiaan A / Sniekers, Suzanne / Taskesen, Erdogan / Watanabe, Kyoko / Blanken, Tessa F / Dekker, Kim / Te Lindert, Bart H W / Wassing, Rick / Jonsdottir, Ingileif / Thorleifsson, Gudmar / Stefansson, Hreinn / Gislason, Thorarinn / Berger, Klaus / Schormair, Barbara / Wellmann, Juergen / Winkelmann, Juliane / Stefansson, Kari / Oexle, Konrad / Van Someren, Eus J W / Posthuma, Danielle. ·Department of Complex Trait Genetics, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands. · Department of Neurology, Amsterdam Neuroscience, Vrije Universiteit Medical Center, Amsterdam, the Netherlands. · Department of Sleep and Cognition, Netherlands Institute for Neuroscience (an institute of the Royal Netherlands Academy of Arts and Sciences), Amsterdam, the Netherlands. · Department of Integrative Neurophysiology, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands. · Department of Psychiatry, Vrije Universiteit Medical Center, Amsterdam, the Netherlands. · deCODE Genetics, Amgen, Inc., Reykjavík, Iceland. · Faculty of Medicine, School of Health Sciences, University of Iceland, Reykjavik, Iceland. · Department of Respiratory Medicine and Sleep, Landspitali, National University Hospital of Iceland, Reykjavik, Iceland. · Institute of Epidemiology and Social Medicine, University of Münster, Münster, Germany. · Institute of Neurogenomics, Helmholtz Zentrum München, Munich, Germany. · Institute of Human Genetics, Technische Universität München, Munich, Germany. · Neurologische Klinik und Poliklinik, Klinikum Rechts der Isar der Technischen Universität München, Munich, Germany. · Munich Cluster for Systems Neurology (SyNergy), Munich, Germany. · Department of Clinical Genetics, Amsterdam Neuroscience, Vrije Universiteit Medical Center, Amsterdam, the Netherlands. ·Nat Genet · Pubmed #28604731.

ABSTRACT: Persistent insomnia is among the most frequent complaints in general practice. To identify genetic factors for insomnia complaints, we performed a genome-wide association study (GWAS) and a genome-wide gene-based association study (GWGAS) in 113,006 individuals. We identify three loci and seven genes associated with insomnia complaints, with the associations for one locus and five genes supported by joint analysis with an independent sample (n = 7,565). Our top association (MEIS1, P < 5 × 10