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Melanoma: HELP
Articles by Neil S. Patel
Based on 2 articles published since 2010
(Why 2 articles?)

Between 2010 and 2020, Neil Patel wrote the following 2 articles about Melanoma.
+ Citations + Abstracts
1 Article Primary Melanoma of the Penis in 3 Patients With Lichen Sclerosus. 2016

Turnbull, Nicholas / Shim, Tang / Patel, Neil / Mazzon, Silvano / Bunker, Christopher. ·Waitemata District Health Board, Milford, Auckland, New Zealand. · Chelsea and Westminster Hospital NHS Foundation Trust, London, England. · East and North Hertfordshire NHS Trust, Hertfordshire, England. ·JAMA Dermatol · Pubmed #26536280.

ABSTRACT: -- No abstract --

2 Article Risk factors for cataract after palladium-103 ophthalmic plaque radiation therapy. 2011

Finger, Paul T / Chin, Kimberly J / Yu, Guo-Pei / Patel, Neil S / Anonymous5020665. ·The New York Eye Cancer Center, New York, NY 10065, USA. ·Int J Radiat Oncol Biol Phys · Pubmed #20615627.

ABSTRACT: PURPOSE: To examine how tumor characteristics and dose affect cataract development after plaque radiation therapy. METHODS AND MATERIALS: Three hundred and eighty-four patients were diagnosed with uveal melanoma and treated with palladium-103 ((103)Pd) plaque radiation therapy. Of these, 282 (74%) inclusion met exclusion criteria for follow-up time, tumor location, and phakic status. Then patient-, ophthalmic-, and radiation-specific factors (patient age, diabetes, hypertension, tumor location, tumor dimensions, and lens dose) were examined (by a Cox proportional regression model) as predictors for the development of radiation-related cataract. RESULTS: Radiation cataract developed in 76 (24%) of patients at a mean follow-up of 39.8 months (range, 1-192). Patients with anteriorly located tumors were noted to have a higher incidence of cataract at 43.0% (43 of 100 patients) vs. 18.1% (33 cataracts per 182 patients) for posteriorly located tumors (p <0.0001). However, multivariate Cox proportional modeling showed that increasing patient age at time of treatment (p for trend = 0.0003) and higher lens dose (p for trend = 0.001) were the best predictors (biomarkers) for radiation cataract. CONCLUSIONS: Although anterior tumor location, greater tumor height, and increased patient age (at treatment) were associated with significantly greater risk for radiation cataract, dose to lens was the most significant factor.