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Mesothelioma: HELP
Articles from Chile
Based on 3 articles published since 2008

These are the 3 published articles about Mesothelioma that originated from Chile during 2008-2019.
+ Citations + Abstracts
1 Article Malignant Mesothelioma of the Tunica Vaginalis Testis: Outcomes Following Surgical Management Beyond Radical Orchiectomy. 2017

Recabal, Pedro / Rosenzweig, Barak / Bazzi, Wassim M / Carver, Brett S / Sheinfeld, Joel. ·Urology Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY; Urology Service, Fundacion Arturo Lopez Perez, Santiago, Chile. Electronic address: pedrorecabal@gmail.com. · Urology Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY. ·Urology · Pubmed #28416299.

ABSTRACT: OBJECTIVE: To describe clinical management and outcomes of a cohort of patients with malignant mesothelioma of the tunica vaginalis testis (MMTVT) who received treatments beyond radical orchiectomy. METHODS: Patients with confirmed MMTVT at a single tertiary care institution were identified. Treatments, pathologic outcomes, and survival were recorded. Prognostic variables associated with survival were analyzed with a Cox proportional hazards model and Kaplan-Meier curves. RESULTS: Overall, 15 patients were included. Initial presentation was a scrotal mass in 7 of 15 (47%) and hydrocele in 5 of 15 (33%) patients. Clinical staging revealed enlarged nodes in 5 of 15 (33%) patients. Radical orchiectomy was the initial treatment in 5 of 15 (33%) patients. Positive surgical margins were found in 6 of 14 (43%) radical orchiectomies and were associated with worse survival (P = .007). The most frequent histologic subtype was epithelioid, associated with better survival (P = .048). Additional surgeries were performed on 12 of 15 (80%) patients. Pathologic examination revealed MMTVT in 6 of 12 (50%) hemiscrotectomies, 7 of 8 (88%) retroperitoneal lymph node dissections, 1 of 7 (14%) pelvic lymph node dissections, and 10 of 10 (100%) groin dissections. Five patients received adjuvant chemotherapy. Two also received adjuvant radiation therapy. Three patients with lymph node involvement remain no evidence of disease over 6 years after diagnosis. After a median follow-up of 3.5 years (interquartile range: 1.2-7.2), 5 patients have died, all of MMTVT; the median overall survival has not been reached. Common sites of relapse were lungs (5 of 7) and groin (3 of 7). CONCLUSION: The pattern of metastatic spread of MMTVT is predominantly lymphatic. Nodes in the retroperitoneum and the groin are commonly involved. Prognosis is poor, but there may be a role for aggressive surgical resection including hemiscrotectomy, and inguinal and retroperitoneal lymph nodes.

2 Article [Benign multicystic peritoneal mesothelioma in a patient with Crohn disease]. 2016

Fluxá, Daniela / Kronberg, Udo / Lubascher, Jaime / O'Brien, Andrés / Las Heras, Facundo / Ibáñez, Patricio / Quera, Rodrigo. ·Departamento de Gastroenterología, Clínica Las Condes, Santiago, Chile. · Unidad de Coloproctología, Clínica Las Condes, Santiago, Chile. · Servicio de Gastroenterología, Clínica Las Condes, Santiago, Chile, rquera@clc.cl. · Departamento de Radiología, Clínica Las Condes, Santiago, Chile. · Departamento de Anatomía Patológica, Clínica Las Condes, Santiago, Chile. ·Rev Med Chil · Pubmed #28393997.

ABSTRACT: Benign multicystic peritoneal mesothelioma is an uncommon lesion arising from the peritoneal mesothelium. It is asymptomatic or presents with unspecific symptoms. Imaging techniques may reveal it, however the final diagnosis can only be made by histopathology. Surgery is the only effective treatment considering its high recurrence rate. We report a 19 years old male with Crohn’s disease. Due to persistent abdominal pain, an abdominal magnetic resonance imaging was performed, showing a complex cystic mass in the lower abdomen. The patient underwent surgery and the lesion was completely resected. The pathological study reported a benign multicystic peritoneal mesothelioma.

3 Article Single site venovenous extracorporeal membrane oxygenation as an alternative to invasive ventilation in post-pneumonectomy fistula with acute respiratory failure. 2012

Fica, Mauricio / Suárez, Francisco / Aparicio, Rodrigo / Suárez, Claudio. ·Thoracic Surgery Division, Santa María Clinic, Santiago, Chile. mfica@csm.cl ·Eur J Cardiothorac Surg · Pubmed #22219410.

ABSTRACT: We report the use of venovenous extracorporeal membrane oxygenation with a single dual lumen cannula in a 42-year-old patient suffering from a post-pneumonectomy fistula and severe respiratory insufficiency, avoiding the classical approach of invasive mechanical ventilation. We discussed the potential advantages of extracorporeal oxygenation as the main support in this particular clinical setting.