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Pancreatic Neoplasms: HELP
Articles by Victor Hugo Fonseca de Jesus
Based on 2 articles published since 2010
(Why 2 articles?)

Between 2010 and 2020, Victor Hugo F. de Jesus wrote the following 2 articles about Pancreatic Neoplasms.
+ Citations + Abstracts
1 Clinical Trial Role of staging laparoscopy in the management of Pancreatic Duct Carcinoma (PDAC): Single-center experience from a tertiary hospital in Brazil. 2018

de Jesus, Victor Hugo Fonseca / da Costa Junior, Wilson Luiz / de Miranda Marques, Tomás Mansur Duarte / Diniz, Alessandro Landskron / de Castro Ribeiro, Héber Salvador / de Godoy, André Luis / de Farias, Igor Correia / Coimbra, Felipe José Fernandez. ·Medical Oncology Department-A.C. Camargo Cancer Center, São Paulo, SP, Brazil. · Abdominal Surgery Department-A.C. Camargo Cancer Center, São Paulo, SP, Brazil. ·J Surg Oncol · Pubmed #29509968.

ABSTRACT: BACKGROUND: Proper staging is critical to the management of pancreatic ductal carcinoma (PDAC). Laparoscopy has been used to stage patients without gross metastatic disease with variable success. OBJECTIVES: We aimed to identify the frequency of patients diagnosed by laparoscopy with occult metastatic disease. Also, we looked for variables related to a higher chance of occult metastasis. METHODS: Patients with PDAC submitted to staging laparoscopy either immediately before pancreatectomy or as a separate procedure between January 2010 and December 2016 were included. None presented gross metastatic disease at initial staging. We used logistic regression to search for variables associated with metastatic disease. RESULTS: The study population consisted of 63 patients. Among all patients, nine (16.7%) had occult metastases at laparoscopy. Unresectable tumor (Odds ratio = 18.0, P = 0.03), increasing tumor size (Odds ratio = 1.36, P = 0.01), and abdominal pain (Odds ratio = 5.6, P = 0.04) significantly predicted the risk of occult metastases in univariate analysis. In multivariate analysis, only tumor size predicted the risk of occult metastases. CONCLUSION: Laparoscopy remains a valuable tool in PDAC staging. Patients with either large or unresectable tumors, or presenting with abdominal pain present the highest risk for occult intra-abdominal metastases.

2 Article Short-term outcomes after vascular resection for pancreatic tumors: Lessons learned from 72 cases from a single Brazilian Cancer Center. 2019

Torres, Silvio Melo / Vaz da Silva, Diego Greatti / Ribeiro, Héber S C / Diniz, Alessandro L / Lobo, Matheus Melo / de Godoy, André Luís / de Farias, Igor Correia / da Costa, Wilson L / de Jesus, Victor Hugo F / Coimbra, Felipe J F. ·Department of Abdominal Surgery, A. C. Camargo Cancer Center, São Paulo, Brazil. · Department of Medicine Epidemiology and Population Sciences, Dan L Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, Texas. · Department of Clinical Oncology, A. C. Camargo Cancer Center, São Paulo, Brazil. ·J Surg Oncol · Pubmed #31808559.

ABSTRACT: INTRODUCTION: Pancreatic malignant tumors are resectable at diagnosis in only 15% to 20% of cases and invasion of vascular structures is commonly present. Therefore, extended resections are needed for adequate local control and negative margins. However, morbidity and mortality associated with these enlarged resections are limiting factors. The aim of this study was to correlate demographic and technical aspects that influenced early and late outcomes. MATERIALS AND METHODS: Between October 2007 and May 2019, 523 pancreatic surgeries were performed, of which 72 required vascular resections. Clinical and histopathological data, surgical techniques, and perioperative parameters were analyzed in a prospectively collected database. RESULTS: Of the 72 cases of vascular resection, 31 were male and 41 females with a mean age of 60.9 years (34-81). The most commonly affected vascular structure was the portal vein (in 40.3%). Free margins were obtained in 77.8% of cases. Postoperative mortality rate at 60 days was 13.9%. American Society of Anesthesiologists (ASA) and age were the most important predictors of major complications. CONCLUSION: Extended resections with vascular involvement in pancreatic surgeries are feasible and safe; furthermore, patient selection plays are key. ASA and age were the most important factors in the decision-making process for extended resections.