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Parkinson Disease: HELP
Articles by Paul Mangal
Based on 3 articles published since 2010
(Why 3 articles?)
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Between 2010 and 2020, Paul Mangal wrote the following 3 articles about Parkinson Disease.
 
+ Citations + Abstracts
1 Clinical Trial The cognition and emotional well-being indices of the Parkinson's disease questionnaire-39: what do they really measure? 2014

Jones, Jacob D / Hass, Chris / Mangal, Paul / Lafo, Jacob / Okun, Michael S / Bowers, Dawn. ·Department of Clinical and Health Psychology, McKnight Brain Institute, University of Florida, Gainesville, FL, USA; Center for Movement Disorders and Neurorestoration, McKnight Brain Institute, University of Florida, Gainesville, FL, USA. · Department of Applied Physiology and Kinesiology, McKnight Brain Institute, University of Florida, Gainesville, FL, USA; Center for Movement Disorders and Neurorestoration, McKnight Brain Institute, University of Florida, Gainesville, FL, USA. · Department of Neurology, McKnight Brain Institute, University of Florida, Gainesville, FL, USA; Center for Movement Disorders and Neurorestoration, McKnight Brain Institute, University of Florida, Gainesville, FL, USA. · Department of Clinical and Health Psychology, McKnight Brain Institute, University of Florida, Gainesville, FL, USA; Department of Neurology, McKnight Brain Institute, University of Florida, Gainesville, FL, USA; Center for Movement Disorders and Neurorestoration, McKnight Brain Institute, University of Florida, Gainesville, FL, USA. Electronic address: dawnbowers@phhp.ufl.edu. ·Parkinsonism Relat Disord · Pubmed #25260967.

ABSTRACT: INTRODUCTION: The Parkinson's disease questionnaire-39 (PDQ-39) is a common measure of health related quality of life (HRQoL) that is widely used with Parkinson disease (PD) patients. Previous evidence suggests that the PDQ-39 reflects at least 8 dimensions (i.e., Emotion, Cognitions, Mobility, etc). To date, little research has examined the external/convergent validity of the Cognitions and Emotional Well-being domains of the PDQ-39. METHODS: A convenience sample of 303 PD patients underwent a comprehensive multi-domain neuropsychological evaluation, including tests of execution function, episodic verbal memory, processing speed, language and working memory, as well as completing measures of depression, apathy, state and trait anxiety and HRQoL (PDQ-39). Hierarchical regressions were conducted in order to examine the relationship between scores on neuropsychological tests and the Cognitions index, as well as mood measures and the Emotional Well-being index of the PDQ-39. RESULTS: Neuropsychological test performance did not account for a significant amount of variance in the PDQ-39 Cognitions index scores. Instead, it was depression that significantly contributed to the Cognitions index, above and beyond neuropsychological performance. The PDQ-39 Emotional Well-being index was also related to mood measures, primarily depression and trait anxiety. CONCLUSIONS: The PDQ-39 Cognition index may be more related to mood functioning, as opposed to cognitive functioning, and should not be considered a "proxy" for cognitive functioning. Future studies are needed to better explain the construct of this index.

2 Article Mood Differences Among Parkinson's Disease Patients With Mild Cognitive Impairment. 2016

Jones, Jacob D / Mangal, Paul / Lafo, Jacob / Okun, Michael S / Bowers, Dawn. ·From the Depts. of Clinical and Health Psychology (JDJ, PM, JL, DB) and Neurology (MSO, DB), Center for Movement Disorders and Neurorestoration, McKnight Brain Institute, University of Florida, Gainesville. ·J Neuropsychiatry Clin Neurosci · Pubmed #26792098.

ABSTRACT: Studies with healthy elderly adults suggest that apathy, depression, and anxiety are more common among individuals with mild cognitive impairment (MCI). This study examined differences in mood/amotivational symptoms among patients with Parkinson's disease (PD) with and without MCI. Patients with PD (N=214) underwent neurocognitive evaluations including assessment of apathy (Apathy Scale), depression (Beck Depression Inventory-II), and trait anxiety (State-Trait Anxiety Inventory trait scale). Trait anxiety and depression were more severe in patients with PD with MCI. Delineation of MCI into amnestic and nonamnestic subtypes revealed greater depression, apathy, and anxiety among patients with PD with amnestic MCI relative to cognitively intact patients with PD. Patients with PD and MCI report greater mood symptoms compared to patients with PD who are cognitively intact.

3 Article Anxiety and Depression Are Better Correlates of Parkinson's Disease Quality of Life Than Apathy. 2015

Jones, Jacob D / Butterfield, London C / Song, Woojin / Lafo, Jacob / Mangal, Paul / Okun, Michael S / Bowers, Dawn. ·From the Dept. of Clinical and Health Psychology (JDJ, LCB, JL, PM, DB), Dept. of Neurology (MSO, DB), and Center for Movement Disorders and Neurorestoration, McKnight Brain Institute, University of Florida, Gainesville, FL · and Dept. of Psychiatry, University of Michigan, Ann Arbor, MI (WS). ·J Neuropsychiatry Clin Neurosci · Pubmed #25162776.

ABSTRACT: Due to controversy regarding the influence of apathy on quality of life (QoL), the authors examined the independent influence of apathy, depression, and trait anxiety in a nondemented sample of patients with Parkinson disease (PD). Participants (N=107) completed standard self-report measures of QoL and mood/motivation. Analyses investigated the contribution of these measures and empirically derived factor scores on QoL. QoL was predicted by trait anxiety, dysphoria, and decreased interest, with no independent contribution of apathy. Different patterns emerged with respect to domain-specific QoL, with trait anxiety being the strongest predictor across most domains. Anxiety was most widely related to QoL in PD, with minimal contribution of apathy. Future studies should examine different roles of PD mood/motivation symptoms on caregiver QoL.