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Parkinson Disease: HELP
Articles from England
Based on 2,454 articles published since 2009

These are the 2454 published articles about Parkinson Disease that originated from England during 2009-2019.
+ Citations + Abstracts
Pages: 1 · 2 · 3 · 4 · 5 · 6 · 7 · 8 · 9 · 10 · 11 · 12 · 13 · 14 · 15 · 16 · 17 · 18 · 19 · 20
1 Guideline Neurogenic bowel dysfunction: Clinical management recommendations of the Neurologic Incontinence Committee of the Fifth International Consultation on Incontinence 2013. 2018

Cotterill, Nikki / Madersbacher, Helmut / Wyndaele, Jean J / Apostolidis, Apostolos / Drake, Marcus J / Gajewski, Jerzy / Heesakkers, John / Panicker, Jalesh / Radziszewski, Piotr / Sakakibara, Ryuji / Sievert, Karl-Dietrich / Hamid, Rizwan / Kessler, Thomas M / Emmanuel, Anton. ·Bristol Urological Institute, North Bristol NHS Trust, Bristol, UK. · University Clinic for Neurourology, Innsbruck, Austria. · University Hospital, Antwerp, Belgium. · Aristotle University of Thessaloniki, Thessaloniki, Greece. · Urology Consultants, Halifax, Canada. · University Medical Center St Radboud, Nijmegen, The Netherlands. · National Hospital for Neurology and Neurosurgery, Queen Square, London, UK. · Medical University of Warsaw, Warsaw, Poland. · Sakura Medical Center, Toho University, Sakura, Japan. · University of Tuebingen, Tuebingen, Germany. · University College London Hospitals, London, UK. · Balgrist University Hospital, Zurich, Switzerland. · St. Mark's Hospital, London, UK. ·Neurourol Urodyn · Pubmed #28640977.

ABSTRACT: BACKGROUND: Evidence-based guidelines for the management of neurological disease and lower bowel dysfunction have been produced by the International Consultations on Incontinence (ICI). These are comprehensive guidelines, and were developed to have world-wide relevance. AIMS: To update clinical management of neurogenic bowel dysfunction from the recommendations of the 4th ICI, 2009. MATERIALS AND METHODS: A series of evidence reviews and updates were performed by members of the working group. The resulting guidelines were presented at the 2012 meeting of the European Association of Urology for consultation, and modifications applied to deliver evidence based conclusions and recommendations for the scientific report of the 5th edition of the ICI in 2013. RESULTS: The current review is a synthesis of the conclusions and recommendations, including the algorithms for initial and specialized management of neurogenic bowel dysfunction. The pathophysiology is described in terms of spinal cord injury, multiple sclerosis, and Parkinson's disease. Assessment requires detailed history and clinical assessment, general investigations, and specialized testing, if required. Treatment primarily focuses on optimizing stool consistency and regulating bowel evacuation to improve quality of life. Symptom management covers conservative and interventional measures to promote good habits and assist stool evacuation, along with prevention of incontinence. Education is essential to achieving optimal bowel management. DISCUSSION: The review offers a pragmatic approach to management in the context of complex pathophysiology and varied evidence base.

2 Guideline Collective physician perspectives on non-oral medication approaches for the management of clinically relevant unresolved issues in Parkinson's disease: Consensus from an international survey and discussion program. 2015

Odin, P / Ray Chaudhuri, K / Slevin, J T / Volkmann, J / Dietrichs, E / Martinez-Martin, P / Krauss, J K / Henriksen, T / Katzenschlager, R / Antonini, A / Rascol, O / Poewe, W / Anonymous2260838. ·Department of Neurology, Lund University Hospital, 221 85 Lund, Sweden; Klinikum-Bremerhaven, D-27574 Bremerhaven, Germany. Electronic address: per.odin@med.lu.se. · King's College London, and National Parkinson Foundation Centre of Excellence, Dept of Neurology, King's College Hospital, London, UK. · Department of Neurology, University of Kentucky College of Medicine, Kentucky Clinic L-445, 740 South Limestone Street, Lexington, KY 40536-0284, USA. · Department of Neurology, University Hospital of Würzburg, 97080 Würzburg, Germany. · Department of Neurology, Oslo University Hospital and University of Oslo, N-0424 Oslo, Norway. · National Center for Epidemiology and CIBERNED, ISCIII, Avenida Monforte de Lemos 5, 28029 Madrid, Spain. · Department of Neurosurgery, Medizinische Hochschule Hannover, Carl-Neuberg-Strasse 1, 30625 Hannover, Germany. · University Hospital of Bispebjerg, Bispebjerg Bakke 23, 2400 København, NV, Denmark. · Department of Neurology and Karl Landsteiner Institute for Neuroimmunological and Neurodegenerative Disorders, Sozialmedizinisches Zentrum Ost - Donauspital, 1220 Wien Langobardenstraße 122, Austria. · Parkinson and Movement Disorders Unit, IRCCS Hospital San Camillo, Venice, Italy. · Clinical Investigation Center 1436 and Department of Clinical Pharmacology, INSERM and University Hospital of Toulouse, Toulouse University, 37 alées Jules Giesde, 31000 Toulouse, France; Clinical Investigation Center 1436 and Department of Neurosciences, INSERM and University Hospital of Toulouse, Toulouse University, 37 alées Jules Giesde, 31000 Toulouse, France. · Innsbruck Medical University/University Hospital, Anichstrasse 35, A-6020 Innsbruck, Austria. ·Parkinsonism Relat Disord · Pubmed #26233582.

ABSTRACT: Navigate PD was an educational program established to supplement existing guidelines and provide recommendations on the management of Parkinson's disease (PD) refractory to oral/transdermal therapies. It involved 103 experts from 13 countries overseen by an International Steering Committee (ISC) of 13 movement disorder specialists. The ISC identified 71 clinical questions important for device-aided management of PD. Fifty-six experts responded to a web-based survey, rating 15 questions as 'critically important;' these were refined to 10 questions by the ISC to be addressed through available evidence and expert opinion. Draft guidance was presented at international/national meetings and revised based on feedback. Key take-home points are: • Patients requiring levodopa >5 times daily who have severe, troublesome 'off' periods (>1-2 h/day) despite optimal oral/transdermal levodopa or non-levodopa-based therapies should be referred for specialist assessment even if disease duration is <4 years. • Cognitive decline related to non-motor fluctuations is an indication for device-aided therapies. If cognitive impairment is mild, use deep brain stimulation (DBS) with caution. For patients who have cognitive impairment or dementia, intrajejunal levodopa infusion is considered as both therapeutic and palliative in some countries. Falls are linked to cognitive decline and are likely to become more frequent with device-aided therapies. • Insufficient control of motor complications (or drug-resistant tremor in the case of DBS) are indications for device-aided therapies. Levodopa-carbidopa intestinal gel infusions or subcutaneous apomorphine pump may be considered for patients aged >70 years who have mild or moderate cognitive impairment, severe depression or other contraindications to DBS.

3 Guideline Consensus statements on driving in people with Parkinson's disease. 2014

Classen, Sherrilene / Anonymous510792 / Anonymous520792. ·School of Occupational Therapy, Elborn College, Western University, London, Ontario, Canada. ·Occup Ther Health Care · Pubmed #24754762.

ABSTRACT: Parkinson's disease (PD) is a complex neurodegenerative disorder leading to motor and non-motor impairments, all of which can affect fitness to drive. The literature suggest that on-road and simulated driving performances are impaired in people with PD, as compared to healthy control drivers. Clear associations exist between impaired driving performance and contrast sensitivity, visual processing speed, and psychomotor speed. Prior to this review and expert panel process, no evidence-based guidelines have existed to help occupational therapy practitioners determining fitness to drive in those with PD. Three consensus statements are presented in this work to enable occupational therapy practitioners and other driver rehabilitation specialists to make fitness to drive determinations in people with PD.

4 Editorial Is neuromelanin the imaging biomarker for the early diagnosis of Parkinson's disease that we were looking for? 2019

Pavese, Nicola. ·Institute of Neuroscience, Faculty of Medical Sciences, Newcastle University, UK; Department of Nuclear Medicine and PET Centre, Aarhus University Hospital, Nørrebrogade 44, 8000, Aarhus, Denmark. Electronic address: nicola.pavese@newcastle.ac.uk. ·Parkinsonism Relat Disord · Pubmed #30578009.

ABSTRACT: -- No abstract --

5 Editorial Taking the 'Disease' out of 'Parkinson's': has the disease had its day? 2019

Worth, Paul F. ·Addenbrooke's Hospital, Cambridge CB2 0QQ, UK paul.worth@addenbrookes.nhs.uk. ·Pract Neurol · Pubmed #30463982.

ABSTRACT: -- No abstract --

6 Editorial Testing the MDS clinical diagnostic criteria for Parkinson's disease. 2018

Schrag, Anette. ·Department of Clinical and Movement Neurosciences, University College London Institute of Neurology, London, United Kingdom. ·Mov Disord · Pubmed #30365218.

ABSTRACT: -- No abstract --

7 Editorial Preface. 2018

Politis, Marios. ·The Neurodegeneration Imaging Group, King's College London. ·Int Rev Neurobiol · Pubmed #30314609.

ABSTRACT: -- No abstract --

8 Editorial Biomedical devices go wild. 2018

Rogers, John / Malliaras, George / Someya, Takao. ·John Rogers, Northwestern University, Evanston, IL 60208, USA. Email: jrogers@northwestern.edu. · George Malliaras, University of Cambridge, Cambridge, UK. Email: gm603@cam.ac.uk. · Takao Someya, University of Tokyo, Tokyo, Japan. Email: someya@ee.t.u-tokyo.ac.jp. ·Sci Adv · Pubmed #30255157.

ABSTRACT: -- No abstract --

9 Editorial Exercise for people with Parkinson's: a practical approach. 2018

Ramaswamy, Bhanu / Jones, Julie / Carroll, Camille. ·Faculty of Health and Wellbeing, Sheffield Hallam University, Sheffield, UK. · School of Health Sciences, Robert Gordon University, Aberdeen, UK. · Faculty of Medicine and Dentistry, University of Plymouth, Plymouth, UK. ·Pract Neurol · Pubmed #29858216.

ABSTRACT: Exercise is key to a healthy and productive life. For people with Parkinson's, exercise has reported benefits for controlling motor and non-motor symptoms alongside the use of pharmacological intervention. For example, exercise prolongs independent mobility and improves sleep, mood, memory and quality of life, all further enhanced through socialisation and multidisciplinary team support. Recent research suggests that optimally prescribed exercise programmes following diagnosis may alter neurophysiological processes, possibly slowing symptom progression.Given its benefits, professionals should encourage and motivate people with Parkinson's to exercise regularly from the time of diagnosis and provide guidance on what exercise to do. We provide examples of how the growing body of evidence on exercise for people with Parkinson's is revolutionising the services they are provided. We also highlight new resources available to help the wider support network (people such as volunteers, partners and friends of people with Parkinson's) with an interest in exercise promote a consistent message on the benefits of exercise.

10 Editorial Are Alzheimer's disease and other neurodegenerative disorders caused by impaired signalling of insulin and other hormones? 2018

Hölscher, Christian / De Felice, Fernanda G / Greig, Nigel H / Ferreira, Sergio T. ·Biomedical and Life Sciences, Lancaster University, Lancaster, UK. Electronic address: c.holscher@lancaster.ac.uk. · Centre for Neuroscience Studies, Department of Biomedical and Molecular Sciences, Queen's University, Kingston, Ontario, Canada. · Drug Design & Development Section, Translational Gerontology Branch, National Institute on Aging, National Institutes of Health, Baltimore, USA. · Institute of Biophysics Carlos Chagas Filho, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil. ·Neuropharmacology · Pubmed #29782874.

ABSTRACT: -- No abstract --

11 Editorial What would James Parkinson think? A virtual dialogue on factors influencing the development of Parkinson's disease. 2017

Schapira, Anthony Hv. ·Department of Clinical Neurosciences, UCL Institute of Neurology, London, UK. ·Mov Disord · Pubmed #29124789.

ABSTRACT: -- No abstract --

12 Editorial To sleep or not to sleep during deep brain stimulation surgery for Parkinson disease? 2017

Aziz, Tipu Z / Hariz, Marwan. ·From the Nuffield Department of Surgical Sciences (T.Z.A.), University of Oxford, John Radcliffe Hospital, Headington · Unit of Functional Neurosurgery (M.H.), UCL Institute of Neurology, London, UK · and Department of Clinical Neuroscience (M.H.), Umeå University, Sweden. ·Neurology · Pubmed #28986412.

ABSTRACT: -- No abstract --

13 Editorial A glimmer of light at the end of the tunnel? 2017

Jenner, Peter. ·Neurodegenerative Diseases Research Group, Institute of Pharmaceutical Sciences, Faculty of Health Sciences and Medicine, King's College, London, United Kingdom. ·Mov Disord · Pubmed #28921664.

ABSTRACT: -- No abstract --

14 Editorial Approaches towards optimizing individualized, high-quality, evidence-informed care. 2017

Chambers, Mary. ·Faculty of Health, Social Care and Education, Kingston University and St. George's University of London. ·Health Expect · Pubmed #28715620.

ABSTRACT: -- No abstract --

15 Editorial Novel evidence associates higher plasma α-synuclein levels and cognitive impairment in Parkinson's disease. 2017

Aarsland, Dag / Rajkumar, Anto P / Hye, Abdul. ·Department of Old Age Psychiatry, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK. · Mental Health of Older Adults and Dementia Clinical Academic Group, South London and Maudsley NHS Foundation Trust, London, UK. · NIHR Biomedical Research Centre for Mental Health and Biomedical Research Unit for Dementia at South London and Maudsley NHS Foundation trust, London, UK. ·J Neurol Neurosurg Psychiatry · Pubmed #28607120.

ABSTRACT: -- No abstract --

16 Editorial No time like the present - two hundred years of Parkinson's disease. 2017

Combes, Robert. ·c/o FRAME, Nottingham, UK. ·Altern Lab Anim · Pubmed #28598191.

ABSTRACT: -- No abstract --

17 Editorial Disrupted identities: movement, mind, and memory in Parkinson's disease. 2017

Leroi, Iracema. ·Department of Neuroscience and Experimental Psychology,University of Manchester,Manchester Academic Health Sciences Centre,UK. ·Int Psychogeriatr · Pubmed #28482941.

ABSTRACT: For the many clinicians au fait with the history of the clinical description of Parkinson's disease, they will be aware that the very earliest description of James Parkinson's "Shaking Palsy" in 1817 explicitly excluded the involvement of cognitive and emotional processes as manifestations of the disease. Within a short time following his treatise, it became all too clear to those in the field that Parkinson's disease is more than just a motor disorder, and as was aptly conceptualized by Paul McHugh, Professor of Psychiatry at Johns Hopkins Hospital from 1975 until 2001, Parkinson's disease is closer to being a "triadic disorder," encompassing motor, cognitive, and psychiatric elements (McHugh, 1989). Even this notion is now outdated, with the triad being accompanied by autonomic, pain, and other non-motor syndromes.

18 Editorial What Would Dr. James Parkinson Think Today? I. The Role of Functional Neurosurgery for Parkinson's Disease. 2017

Hariz, Marwan / Obeso, Jose A. ·UCL-Institute of Neurology, London, United Kingdom. · Department of Clinical Neuroscience, Umeå University, Umeå, Sweden. · CINAC-HM Puerta del Sur, Mostoles and CEU-San Pablo University, Madrid, Spain. · CIBERNED, Insituto Carlos III, Madrid, Spain. ·Mov Disord · Pubmed #28124429.

ABSTRACT: -- No abstract --

19 Editorial Anatomo-functional basis of nonmotor symptoms in Parkinson disease. 2016

Mano, Tadaaki / Britton, Zelie / Britton, Thomas. ·From Gifu University of Medical Science (T.M.), Japan · Imperial College London (Z.B.) · and King's College Hospital (T.B), London, UK. ·Neurology · Pubmed #27856780.

ABSTRACT: -- No abstract --

20 Editorial Functions of the basal ganglia-paradox or no paradox? 2016

Crossman, Alan R / Obeso, Jose A. ·University of Manchester, Manchester, UK. · HM CINAC, HM Puerta del Sur, Mostoles, Madrid, Universidad CEU San Pablo, Madrid, Spain. · Center for Networked Biomedical Research on Neurodegenerative Diseases, Madrid, Spain. ·Mov Disord · Pubmed #27506637.

ABSTRACT: -- No abstract --

21 Editorial Progression and biomarkers for Parkinson disease: Merging motor with nonmotor symptoms. 2016

Chaudhuri, K Ray. ·From the National Parkinson Foundation International Centre of Excellence, King's College London; National Institute for Health Research (NIHR) Mental Health Biomedical Research Centre and Dementia Unit at South London and Maudsley NHS Foundation Trust; and The Maurice Wohl Clinical Neuroscience Institute, Kings College London, UK. ray.chaudhuri@kcl.ac.uk. ·Neurology · Pubmed #27164660.

ABSTRACT: -- No abstract --

22 Editorial Depression: to screen or not to screen? 2015

Anderson, David. ·Mersey Care NHS Trust, Liverpool, UK. ·Age Ageing · Pubmed #26259949.

ABSTRACT: -- No abstract --

23 Editorial A new scale for the assessment of pain in Parkinson's disease. 2015

Schrag, Anette. ·Department of Clinical Neurosciences, UCL Institute of Neurology, London, United Kingdom. ·Mov Disord · Pubmed #26230748.

ABSTRACT: -- No abstract --

24 Editorial Body-worn sensors--the brave new world of clinical measurement? 2015

Maetzler, Walter / Rochester, Lynn. ·Department of Neurodegeneration, Hertie Institute for Clinical Brain Research (HIH), University of Tuebingen, Tuebingen, Germany. · German Center for Neurodegenerative Diseases (DZNE), Tuebingen, Germany. · Institute of Neuroscience, Newcastle University, Newcastle upon Tyne, United Kingdom. ·Mov Disord · Pubmed #26173577.

ABSTRACT: -- No abstract --

25 Editorial Multidisciplinary rehabilitation in Parkinson's disease: A milestone with future challenges. 2015

Rochester, Lynn / Espay, Alberto J. ·Institute of Neuroscience, Newcastle University, Clinical Ageing Research Unit, Campus for Ageing and Vitality, Newcastle upon Tyne, UK. · James J. and Joan A. Gardner Family Center for Parkinson's Disease and Movement Disorders, University of Cincinnati, Cincinnati, Ohio, USA. ·Mov Disord · Pubmed #26096805.

ABSTRACT: -- No abstract --