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Pulmonary Embolism HELP
Based on 11,626 articles published since 2008
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These are the 11626 published articles about Pulmonary Embolism that originated from Worldwide during 2008-2019.
 
+ Citations + Abstracts
Pages: 1 · 2 · 3 · 4 · 5 · 6 · 7 · 8 · 9 · 10 · 11 · 12 · 13 · 14 · 15 · 16 · 17 · 18 · 19 · 20
1 Guideline British Thoracic Society Guideline for the initial outpatient management of pulmonary embolism (PE). 2018

Howard, Luke S G E / Barden, Steven / Condliffe, Robin / Connolly, Vincent / Davies, Christopher W H / Donaldson, James / Everett, Bernard / Free, Catherine / Horner, Daniel / Hunter, Laura / Kaler, Jasvinder / Nelson-Piercy, Catherine / O-Dowd, Emma / Patel, Raj / Preston, Wendy / Sheares, Karen / Campbell, Tait. ·National Pulmonary Hypertension Service, Hammersmith Hospital, Imperial College Healthcare NHS Trust, London, UK. · Royal Sussex County Hospital, Brighton, UK. · Royal Hallamshire Hospital, Sheffield, UK. · South Tees Hospitals NHS Trust, Middlesbrough, UK. · Department of Respiratory Medicine, Royal Berkshire Hospital, Reading, UK. · Derby Teaching Hospitals NHS Foundation Trust. · Chesterfield, UK. · Department of Respiratory Medicine, George Eliot Hospital, Nuneaton, UK. · Emergency Department, Salford Royal NHS Foundation Trust, Salford, UK. · The Royal College of Emergency Medicine, London, UK. · St Thomas' Hospital, London, UK. · Cardiovascular Department, Guy's and St Thomas' NHS Foundation Trust, London, UK. · Women's health academic centre, Guy's and Saint Thomas' NHS Foundation Trust, London, UK. · Department of Respiratory Medicine, Nottingham City Hospital, Nottingham, UK. · King's College Hospital NHS Foundation Trust, London, UK. · George Eliot Hospital NHS Trust, Nuneaton, UK. · Royal Papworth Hospital NHS Foundation Trust, Cambridge, UK. · Haematology, Glasgow Royal Infirmary, Glasgow, UK. ·Thorax · Pubmed #29898978.

ABSTRACT: -- No abstract --

2 Guideline Society of Interventional Radiology Position Statement on Catheter-Directed Therapy for Acute Pulmonary Embolism. 2018

Kuo, William T / Sista, Akhilesh K / Faintuch, Salomão / Dariushnia, Sean R / Baerlocher, Mark O / Lookstein, Robert A / Haskal, Ziv J / Nikolic, Boris / Gemmete, Joseph J. ·Division of Vascular and Interventional Radiology, Department of Radiology, Stanford University Medical Center, 300 Pasteur Dr., H-3651, Stanford, CA 94305-5642. Electronic address: wkuo@stanford.edu. · Division of Vascular and Interventional Radiology, Department of Radiology, New York University Langone School of Medicine, New York, New York. · Division of Interventional Radiology, Beth Israel Deaconess Medical Center, Boston, Massachusetts. · Department of Radiology, Division of Interventional Radiology and Image-Guided Medicine, Emory University School of Medicine, Atlanta, Georgia. · Department of Interventional Radiology, Royal Victoria Hospital, Barrie, Ontario, Canada. · Division of Vascular and Interventional Radiology, Mount Sinai Health System, New York, New York. · Division of Vascular and Interventional Radiology, Department of Radiology and Medical Imaging, University of Virginia School of Medicine, Charlottesville, Virginia. · Department of Radiology, Stratton Medical Center, Albany, New York. · Departments of Radiology and Neurosurgery, University of Michigan Hospitals, Ann Arbor, Michigan. ·J Vasc Interv Radiol · Pubmed #29422427.

ABSTRACT: -- No abstract --

3 Guideline The American Society of Colon and Rectal Surgeons Clinical Practice Guideline for the Prevention of Venous Thromboembolic Disease in Colorectal Surgery. 2018

Fleming, Fergal / Gaertner, Wolfgang / Ternent, Charles A / Finlayson, Emily / Herzig, Daniel / Paquette, Ian M / Feingold, Daniel L / Steele, Scott R. ·Prepared by the Clinical Practice Guidelines Committee of The American Society of Colon and Rectal Surgeons. ·Dis Colon Rectum · Pubmed #29219916.

ABSTRACT: -- No abstract --

4 Guideline Recommendations for standardized risk factor definitions in pediatric hospital-acquired venous thromboembolism to inform future prevention trials: communication from the SSC of the ISTH. 2017

Branchford, B R / Mahajerin, A / Raffini, L / Chalmers, E / van Ommen, C H / Chan, A K C / Goldenberg, N A / Anonymous3591006. ·Department of Pediatrics, Section of Hematology/Oncology and the Hemophilia and Thrombosis Center, University of Colorado School of Medicine and Children's Hospital Colorado, Aurora, CO, USA. · Division of Hematology, CHOC Children's Specialists, Orange, CA, USA. · Department of Pediatrics, Division of Hematology, The Children's Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, PA, USA. · Department of Haematology, Royal Hospital for Sick Children, Yorkhill, Glasgow, UK. · Department of Pediatric Haematology, Emma Children's Hospital/Academic Medical Centre, Amsterdam, the Netherlands. · Division of Hematology/Oncology, Department of Pediatrics, McMaster University, Hamilton, ON, Canada. · Division of Hematology, Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, MD, USA. · Johns Hopkins Medicine Pediatric Thrombosis Program, Johns Hopkins All Children's Hospital, St. Petersburg, FL, USA. · Johns Hopkins Children's Center, Baltimore, MD, USA. · All Children's Research Institute, Johns Hopkins All Children's Hospital, St. Petersburg, FL, USA. ·J Thromb Haemost · Pubmed #29027741.

ABSTRACT: -- No abstract --

5 Guideline [A statement the Polish Cardiac Society Working Group on Pulmonary Circulation on screening for CTEPH patients after acute pulmonary embolism]. 2017

Ciurzyński, Michał / Kurzyna, Marcin / Kopeć, Grzegorz / Błaszczak, Piotr / Chrzanowski, Łukasz / Kamiński, Karol / Mizia-Stec, Katarzyna / Mularek-Kubzdela, Tatiana / Mroczek, Ewa / Biederman, Andrzej / Pruszczyk, Piotr / Torbicki, Adam. ·Klinika Chorób Wewnętrznych i Kardiologii z Centrum Diagnostyki i Leczenia Żylnej Choroby Zakrzepowo Zatorowej, Warszawski Uniwersytet Medyczny, Warszawa, Polska. michal.ciurzynski@wum.edu.pl. ·Kardiol Pol · Pubmed #28628189.

ABSTRACT: Both pharmacological and invasive treatment of chronic thromboembolic pulmonary hypertension (CTEPH) is now available in Poland and the awareness of the disease among physicians is growing. Thus, the Polish Cardiac Society's Working Group on Pulmonary Circulation in cooperation with independent experts in this field, have launched the statement on algorithm to guide a CTEPH diagnosis in patients with previous acute pulmonary embolism (APE). In Poland, every year this disease affects about 250 patients. CTEPH should be suspected in individuals after APE with dyspnea, despite at least 3 months period of effective anticoagulation, particularly when specified risk factors are present. Echocardiography is a main screening tool. The authors suggest that a diagnostic process of patients with significant clinical suspicion of CTEPH and right ventricle overload in echocardiography should be performed in reference centres. The document contains a list of Polish centres diagnosing patients with suspected CTEPH. Pulmonary scintigraphy is a safe and highly sensitive screening test for CTEPH. Multi-detector computed tomography with precise detection of thromboembolic residues in pulmonary circulation is important for planning of pulmonary endarterectomy. Right heart catheterisation definitely confirms the presence of pulmonary hypertension and direct pulmonary angiography allows for identification of lesions suitable for thromboendarterectomy or pulmonary balloon angioplasty. In this document a diagnostic algorithm in patients with suspected CTEPH is also proposed. With individualised sequential diagnostic strategy each patient can be finally qualified for a particular mode of therapy by dedicated CTEPH Heart Team. Moreover the document contains short information for the primary care physician about the management of patients after APE.

6 Guideline ACR Appropriateness Criteria 2017

Anonymous3740905 / Kirsch, Jacobo / Brown, Richard K J / Henry, Travis S / Javidan-Nejad, Cylen / Jokerst, Clinton / Julsrud, Paul R / Kanne, Jeffrey P / Kramer, Christopher M / Leipsic, Jonathon A / Panchal, Kalpesh K / Ravenel, James G / Shah, Amar B / Mohammed, Tan-Lucien / Woodard, Pamela K / Abbara, Suhny. ·Principal Author, Cleveland Clinic, Weston, Florida. Electronic address: kirschj@gmail.com. · University Hospital, Ann Arbor, Michigan. · University of California San Francisco, San Francisco, California. · Mallinckrodt Institute of Radiology, Washington University School of Medicine, Saint Louis, Missouri. · Banner University Medical Center, Tucson, Arizona. · Mayo Clinic, Rochester, Minnesota. · University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin. · University of Virginia Health System, Charlottesville, Virginia; American College of Cardiology. · St. Paul's Hospital, Vancouver, British Columbia, Canada. · University of Cincinnati Hospital, Cincinnati, Ohio. · Medical University of South Carolina, Charleston, South Carolina. · Westchester Medical Center, Valhalla, New York. · Specialty Chair, University of Florida College of Medicine, Gainesville, Florida. · Specialty Chair, Mallinckrodt Institute of Radiology, Washington University School of Medicine, Saint Louis, Missouri. · Panel Chair, UT Southwestern Medical Center, Dallas, Texas. ·J Am Coll Radiol · Pubmed #28473076.

ABSTRACT: Pulmonary embolism (PE) remains a common and important clinical condition that cannot be accurately diagnosed on the basis of signs, symptoms, and history alone. The diagnosis of PE has been facilitated by technical advancements and multidetector CT pulmonary angiography, which is the major diagnostic modality currently used. Ventilation and perfusion scans remain largely accurate and useful in certain settings. Lower-extremity ultrasound can substitute by demonstrating deep vein thrombosis; however, if negative, further studies to exclude PE are indicated. In all cases, correlation with the clinical status, particularly with risk factors, improves not only the accuracy of diagnostic imaging but also overall utilization. Other diagnostic tests have limited roles. The American College of Radiology Appropriateness Criteria are evidence-based guidelines for specific clinical conditions that are reviewed annually by a multidisciplinary expert panel. The guideline development and revision include an extensive analysis of current medical literature from peer-reviewed journals and the application of well-established methodologies (RAND/UCLA Appropriateness Method and Grading of Recommendations Assessment, Development, and Evaluation or GRADE) to rate the appropriateness of imaging and treatment procedures for specific clinical scenarios. In those instances where evidence is lacking or equivocal, expert opinion may supplement the available evidence to recommend imaging or treatment.

7 Guideline Clinical Pharmacogenetic Testing and Application: Laboratory Medicine Clinical Practice Guidelines. 2017

Kim, Sollip / Yun, Yeo Min / Chae, Hyo Jin / Cho, Hyun Jung / Ji, Misuk / Kim, In Suk / Wee, Kyung A / Lee, Woochang / Song, Sang Hoon / Woo, Hye In / Lee, Soo Youn / Chun, Sail. ·Department of Laboratory Medicine, Ilsan Paik Hospital, Inje University College of Medicine, Goyang, Korea. · Department of Laboratory Medicine, Konkuk University Medical Center, Konkuk University School of Medicine, Seoul, Korea. · Department of Laboratory Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea. · Department of Laboratory Medicine, Konyang University Hospital, College of Medicine, Konyang University, Daejeon, Korea. · Department of Laboratory Medicine, Veterans Health Service Medical Center, Seoul, Korea. · Department of Laboratory Medicine, School of Medicine, Pusan National University, Busan, Korea. · Department of Laboratory Medicine, Yonsei University College of Medicine, Seoul, Korea. · Department of Laboratory Medicine, University of Ulsan College of Medicine and Asan Medical Center, Seoul, Korea. · Department of Laboratory Medicine, Seoul National University Hospital and College of Medicine, Seoul, Korea. · Department of Laboratory Medicine, Samsung Changwon Hospital, Sungkyunkwan University School of Medicine, Changwon, Korea. · Department of Laboratory Medicine and Genetics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea. suddenbz@skku.edu. · Department of Laboratory Medicine, University of Ulsan College of Medicine and Asan Medical Center, Seoul, Korea. sailchun@amc.seoul.kr. ·Ann Lab Med · Pubmed #28029011.

ABSTRACT: Pharmacogenetic testing for clinical applications is steadily increasing. Correct and adequate use of pharmacogenetic tests is important to reduce unnecessary medical costs and adverse patient outcomes. This document contains recommended pharmacogenetic testing guidelines for clinical application, interpretation, and result reporting through a literature review and evidence-based expert opinions for the clinical pharmacogenetic testing covered by public medical insurance in Korea. This document aims to improve the utility of pharmacogenetic testing in routine clinical settings.

8 Guideline Combined hormonal contraception and the risk of venous thromboembolism: a guideline. 2017

Anonymous330886 / Anonymous340886. ·American Society for Reproductive Medicine, Birmingham, Alabama. ·Fertil Steril · Pubmed #27793376.

ABSTRACT: While venous thromboembolism (VTE) is rare in young women of reproductive age, combined oral contraceptives increase the risk of VTE. In the patient in whom combined hormonal contraception is appropriate, it is reasonable to use any currently available preparation.

9 Guideline [ANMCO Position paper: Recommendations for the follow-up of patients with pulmonary thromboembolism]. 2016

D'Agostino, Carlo / Zonzin, Pietro / Enea, Iolanda / Gulizia, Michele Massimo / Ageno, Walter / Agostoni, Piergiuseppe / Azzarito, Michele / Becattini, Cecilia / Bongarzoni, Amedeo / Bux, Francesca / Casazza, Franco / Corrieri, Nicoletta / D'Alto, Michele / D'Amato, Nicola / D'Armini, Andrea Maria / De Natale, Maria Grazia / Di Minno, Giovanni / Favretto, Giuseppe / Filippi, Lucia / Grazioli, Valentina / Palareti, Gualtiero / Pesavento, Raffaele / Roncon, Loris / Scelsi, Laura / Tufano, Antonella. ·U.O.C. Cardiologia Ospedaliera, Azienda Ospedaliero-Universitaria Policlinico, Bari. · U.O.C. Cardiologia, Presidio Ospedaliero, Rovigo. · U.O.C. Medicina d'Urgenza, A.O.R.N. S. Anna e S. Sebastiano, Caserta. · U.O.C. Cardiologia, Ospedale Garibaldi-Nesima, Azienda Rilievo Nazionale e Alta Specializzazione "Garibaldi", Catania. · Dipartimento di Medicina Clinica e Sperimentale, Università dell'Insubria, Varese. · Centro Cardiologico Monzino, IRCCS, Milano. · Servizio di Cardiologia, Ospedale San Carlo di Nancy, Roma. · Medicina Interna e Vascolare, Azienda Ospedaliera di Perugia, Perugia. · U.O.C. Cardiologia, Ospedale San Carlo Borromeo, Milano. · U.O.C. Cardiologia-UTIC, Ospedale Di Venere ASL, Bari. · Fondazione Moscati, Buccinasco (MI). · Dipartimento di Scienze Cliniche e di Comunità, Università degli Studi, Milano. · U.O.C. Cardiologia-SUN, A.O.R.N. dei Colli-A.O. Monaldi, Napoli. · Chirurgia Cardio-Toracica, Università degli Studi, Fondazione IRCSS Policlinico San Matteo, Pavia. · Centro per le Coagulopatie, Università degli Studi "Federico II", Napoli. · U.O. Cardiologia Riabilitativa e Preventiva, Ospedale Riabilitativo Alta Specializzazione, Motta di Livenza (TV). · Dipartimento di Scienze Cardiologiche, Toraciche e Vascolari, Università degli Studi, Padova. · Divisione di Angiologia e Malattie della Coagulazione, Policlinico S. Orsola-Malpighi, Università degli Studi, Bologna. · U.O.C. Cardiologia, Ospedale S. Maria della Misericordia, Rovigo. · S.C. Cardiologia, Fondazione IRCSS Policlinico San Matteo, Pavia. ·G Ital Cardiol (Rome) · Pubmed #27869893.

ABSTRACT: Venous thromboembolism (VTE), including deep venous thrombosis and pulmonary embolism, is the third most common cause of cardiovascular death. The management of the acute phase of VTE is well described in several papers and guidelines, whereas the management of the follow-up of the patients affected from VTE is less defined. This position paper of the Italian Association of Hospital Cardiologists (ANMCO) tries to fill the gap using currently available evidence and the opinion of the experts to suggest the most useful way to manage patients in the chronic phase.The clinical and laboratory tests acquired during the acute phase of the disease drives the decision of the following period. Acquired or congenital thrombophilic factors may be identified to explain an apparently not provoked VTE. In some patients, a not yet clinically evident cancer could be the trigger of VTE and this could lead to a different strategy. The main target of the post-acute management is to prevent relapse of the disease and to identify those patients who could worsen or develop chronic thromboembolic pulmonary hypertension. The knowledge of the etiopathogenetic ground is important to address the therapeutic approach, choosing the best antithrombotic strategy and deciding how long therapy should last. During the follow-up period, prognostic stratification should be updated on the basis of new evidences eventually acquired.Treatment of VTE is mainly based on oral or parenteral anticoagulation. Oral direct inhibitors of coagulation represent an interesting new therapy for the acute and extended period of treatment.

10 Guideline [ANMCO position paper: Use of new oral anticoagulants for the treatment and prevention of pulmonary thromboembolism]. 2016

Enea, Iolanda / Roncon, Loris / Gulizia, Michele Massimo / Azzarito, Michele / Becattini, Cecilia / Bongarzoni, Amedeo / Casazza, Franco / Cuccia, Claudio / D'Agostino, Carlo / Rugolotto, Matteo / Vatrano, Marco / Vinci, Eugenio / Fenaroli, Paride / Formigli, Dario / Silvestri, Paolo / Nardi, Federico / Vedovati, Maria Cristina / Scherillo, Marino. ·U.O.C. Medicina d'Urgenza, A.O.R.N. S. Anna e S. Sebastiano, Caserta. · U.O.C. Cardiologia, Ospedale S. Maria della Misericordia, Rovigo. · U.O.C. Cardiologia, Ospedale Garibaldi-Nesima, Azienda di Rilievo Nazionale e Alta Specializzazione "Garibaldi", Catania. · Servizio di Cardiologia, Ospedale San Carlo di Nancy, Roma. · Medicina Interna e Vascolare, Azienda Ospedaliera di Perugia, Perugia. · U.O.C. Cardiologia, Ospedale San Carlo Borromeo, Milano. · Fondazione Moscati, Buccinasco (MI). · U.O. Cardiologia, Istituto Ospedaliero Fondazione Poliambulanza, Brescia. · U.O.C. Cardiologia Ospedaliera, Azienda Ospedaliero-Universitaria Policlinico, Bari. · U.O.C. Cardiologia, Ospedale Ca' Foncello, Treviso. · UTIC-Emodinamica e Cardiologia Interventistica, Ospedale Civile Pugliese, Catanzaro. · U.O.C. Cardiologia-UTIC, Ospedale Umberto I, Siracusa. · U.O. Nefrologia e Dialisi, IRCCS Fondazione Salvatore Maugeri, Università degli Studi, Pavia. · Cardiologia Interventistica-UTIC, A.O. G. Rummo, Benevento. · S.O.C. Cardiologia, Ospedale Castelli, Verbania. · Medicina Interna e Vascolare, Ospedale S. Maria della Misericordia, Università degli Studi, Perugia. ·G Ital Cardiol (Rome) · Pubmed #27869892.

ABSTRACT: The new oral anticoagulants (NOACs) have radically changed the approach to the treatment and prevention of thromboembolic pulmonary embolism. The authors of this position paper face, in succession, issues concerning NOACs, including 1) their mechanism of action, pharmacodynamics and pharmacokinetics; 2) the use in the acute phase with the "double drug single dose" approach or with "single drug double dose"; 3) the use in the extended phase with demonstrated efficacy and with low incidence of bleeding events; 4) the encouraging use of NOACs in particular subgroups of patients such as those with cancer, the ones under- or overweight, with renal insufficiency (creatinine clearance >30 ml/min), the elderly (>75 years); 5) they propose a possible laboratory clinical pathway for follow-up; 6) carry out an examination on the main drug interactions, their potential bleeding risk, and the way to deal with some bleeding complications. The authors conclude that the use of NOACs both in the acute phase and in the extended phase is equally effective to conventional therapy and associated with fewer major bleeding events, which make their use in patients at higher risk of recurrences safer.

11 Guideline [Clinical guidelines for the diagnosis and treatment of chronic thromboembolic pulmonary hypertension (Part 2)]. 2016

Chazova, I E / Martynyuk, T V. ·A.L. Myasnikov Institute of Clinical Cardiology, Russian Cardiology Research and Production Complex, Ministry of Health of the Russian Federation, Moscow, Russia. ·Ter Arkh · Pubmed #27801422.

ABSTRACT: The paper gives current approaches to treating chronic thromboembolic pulmonary hypertension (CTEPH) from the document «Federal Guidelines for the Diagnosis and Treatment of CTEPH» approved at the Third Russian Congress on Pulmonary Hypertension on December 11, 2015. The guidelines had been elaborated to optimize the treatment of patients with CTEPH on the basis of an analysis of the data of the present-day registries and multicenter randomized clinical trials, national and international guidelines and consensus documents, and documents published in recent years. CTEPH is a unique form of pulmonary hypertension since it is potentially curable by surgical treatment. The paper presents indications for and contraindications to pulmonary thromboendartectomy; preparation for surgery; operating room facilities; the specific features of postoperative management and possible complications; and long-term RESULTS: In terms of therapy, in addition to non-pharmacological measures, the authors discuss maintenance and specific treatment options for CTEPH, balloon pulmonary angioplasty, and lung/heart-lung transplantation. In conclusion they propose a management algorithm in patients with CTEPH and requirements for its problem to the center of experts.

12 Guideline [Clinical guidelines for the diagnosis and treatment of chronic thromboembolic pulmonary hypertension (Part 1)]. 2016

Chazova, I E / Martynyuk, T V. ·A.L. Myasnikov Institute of Clinical Cardiology, Russian Cardiology Research and Production Complex, Ministry of Health of the Russian Federation, Moscow, Russia. ·Ter Arkh · Pubmed #27735920.

ABSTRACT: Chronic thromboembolic pulmonary hypertension (CTEPH) is precapillary pulmonary hypertension, in which chronic obstruction of large and middle branches of pulmonary arteries (PAs) and secondary changes in the lung microcirculatory bed result in a progressive increase in pulmonary vascular resistance and PA pressure with the development of severe right cardiac dysfunction and heart failure. CTEPH is a unique form of pulmonary hypertension since it is potentially curable by surgical treatment. The diagnostic criteria for CTEPH are a mean PA pressure of ≥25 mm Hg, as evidenced by right heart catheterization; a PA wedge pressure of ≤15 mm Hg; a pulmonary vascular resistance of >2 Wood units; the presence of chronic/organized thrombi/emboli in the elastic PAs (pulmonary trunk, lobular, segmental, subsegmental PAs); effective anticoagulant therapy at therapeutic dosages over at least 3 months. Up to now, our country has had no guidelines for the diagnosis and treatment of this rare severe disease that, when appropriately untreated, has an extremely poor prognosis. The main task in the preparation of this document was to generalize and analyze the data of current registries, multicenter randomized clinical trials, national and international guidelines, and consensus documents recently published on this problem in order to optimize a diagnostic process and treatment in this category of patients. Part 1 gives a definition of CTEPH, its place in the clinical classification, epidemiology and prognosis, risk factors, pathogenesis and morphology, diagnostic approaches and determination of operability in patients, and specific features of differential diagnosis.

13 Guideline [Update on Current Care Guideline: Venous thromboembolism (VTE): deep venous thrombosis and pulmonary embolism]. 2016

Anonymous2080868. · ·Duodecim · Pubmed #27188093.

ABSTRACT: Key recommendations in management of VTE include prompt and systematic diagnostics based on clinical probability, D-dimer testing and imaging studies, and individualized antithrombotic treatment. Outpatient management is encouraged for patients with favourable prognosis. Interventions such as thrombolysis, venous stenting and inferior vena cava filters are limited to specific subgroups of patients. The duration of anticoagulation is tailored by balancing the risks of VTE recurrence and bleeding. Without contraindications, the minimal duration of anticoagulation is 3 months. The selection between warfarin, direct oral anticoagulants (apixaban, dabigatran, rivaroxaban) and low molecular weight heparin is based on individual patient characteristics and suitability of each drug.

14 Guideline Treatment of pregnancy-associated venous thromboembolism - position paper from the Working Group in Women's Health of the Society of Thrombosis and Haemostasis (GTH). 2016

Linnemann, Birgit / Scholz, Ute / Rott, Hannelore / Halimeh, Susan / Zotz, Rainer / Gerhardt, Andrea / Toth, Bettina / Bauersachs, Rupert / Anonymous1750864. ·1 Medical Practice of Angiology and Haemostaseology, Praxis am Grüneburgweg, Frankfurt/Main, Germany. · 2 Zentrum für Blutgerinnungsstörungen, MVZ Labor Dr. Reising-Ackermann und Kollegen, Leipzig, Germany. · 3 Gerinnungszentrum Rhein Ruhr, Duisburg, Germany. · 4 Centrum für Blutgerinnungsstörungen und Transfusionsmedizin, Düsseldorf, Germany. · 5 Blutgerinnung Ulm, Germany. · 6 Gynäkologische Endokrinologie und Fertilitätsstörungen, Ruprecht-Karls-Universität Heidelberg, Germany. · 7 Klinikum Darmstadt, Klinik für Gefäßmedizin - Angiologie, Darmstadt, Germany. · 8 Centrum für Thrombose und Hämostase, Johannes-Gutenberg-Universität, Mainz, Germany. ·Vasa · Pubmed #27058796.

ABSTRACT: Venous thromboembolism (VTE) is a major cause of maternal morbidity during pregnancy and the postpartum period. However, because there is a lack of adequate study data, management strategies for pregnancy-associated VTE must be deduced from observational stu-dies and extrapolated from recommendations for non-pregnant patients. In this review, the members of the Working Group in Women's Health of the Society of Thrombosis and Haemostasis (GTH) have summarised the evidence that is currently available in the literature to provide a practical approach for treating pregnancy-associated VTE. Because heparins do not cross the placenta, weight-adjusted therapeutic-dose low molecular weight heparin (LMWH) is the anticoagulant treatment of choice in cases of acute VTE during pregnancy. No differences between once and twice daily LMWH dosing regimens have been reported, but twice daily dosing seems to be advisable, at least peripartally. It remains unclear whether determining dose adjustments according to factor Xa activities during pregnancy provides any benefit. Management of delivery deserves attention and mainly depends on the time interval between the diagnosis of VTE and the expected delivery date. In particular, if VTE manifests at term, delivery should be attended by an experienced multidisciplinary team. In lactating women, an overlapping switch from LMWH to warfarin is possible. Anticoagulation should be continued for at least 6 weeks postpartum or for a minimum period of 3 months. Although recommendations are provided for the treatment of pregnancy-associated VTE, there is an urgent need for well-designed prospective studies that compare different management strategies and define the optimal duration and intensity of anticoagulant treatment.

15 Guideline Diagnosis of pregnancy-associated venous thromboembolism - position paper of the Working Group in Women's Health of the Society of Thrombosis and Haemostasis (GTH). 2016

Linnemann, Birgit / Bauersachs, Rupert / Rott, Hannelore / Halimeh, Susan / Zotz, Rainer / Gerhardt, Andrea / Boddenberg-Pätzold, Barbara / Toth, Bettina / Scholz, Ute / Anonymous1740864. ·1 Medical Practice of Angiology and Haemostaseology, Praxis am Grüneburgweg, Frankfurt/Main, Germany. · 2 Klinikum Darmstadt, Klinik für Gefäßmedizin - Angiologie, Darmstadt, Germany. · 9 Centrum für Thrombose und Hämostase (CTH), Johannes-Gutenberg-Universität, Mainz, Germany. · 3 Gerinnungszentrum Rhein Ruhr, Duisburg, Germany. · 4 Centrum für Blutgerinnungsstörungen und Transfusionsmedizin, Düsseldorf, Germany. · 5 Blutgerinnung Ulm, Germany. · 6 Nuramed, Gemeinschaftspraxis für Radiologie und Nuklearmedizin, Köln, Germany. · 7 Gynäkologische Endokrinologie und Fertilitätsstörungen, Ruprecht-Karls-Universität Heidelberg. · 8 Zentrum für Blutgerinnungsstörungen, MVZ Labor Dr. Reising-Ackermann und Kollegen, Leipzig, Germany. ·Vasa · Pubmed #27058795.

ABSTRACT: Pregnancy and the postpartum period are associated with an increased risk of venous thromboembolism (VTE). Over the past decade, new diagnostic algorithms have been established, combining clinical probability, laboratory testing and imaging studies for the diagnosis of deep vein thrombosis (DVT) and pulmonary embolism (PE) in the non-pregnant population. However, there is no such generally accepted algorithm for the diagnosis of pregnancy-associated VTE. Studies establishing clinical prediction rules have excluded pregnant women, and prediction scores currently in use have not been prospectively validated in pregnancy or during the postpartum period. D-dimers physiologically increase throughout pregnancy and peak at delivery, so a negative D-dimer test result, based on the reference values of non-pregnant subjects, becomes unlikely in the second and third trimesters. Imaging studies therefore play a major role in confirming suspected DVT or PE in pregnant women. Major concerns have been raised against radiologic imaging because of foetal radiation exposure, and doubts about the diagnostic value of ultrasound techniques in attempting to exclude isolated iliac vein thrombosis grow stronger as pregnancy progresses. As members of the Working Group in Women's Health of the Society of Thrombosis and Haemostasis (GTH), we summarise evidence from the available literature and aim to establish a more uniform strategy for diagnosing pregnancy-associated VTE.

16 Guideline [Diagnosis and management of acute pulmonary embolism. ESC guidelines 2014]. 2015

Saar, J A / Maack, C / Anonymous6050850. ·Klinik für Innere Medizin III, Kardiologie, Angiologie und internistische Intensivmedizin, Universitätsklinikum des Saarlandes, 66421, Homburg/Saar, Deutschland. · Klinik für Innere Medizin III, Kardiologie, Angiologie und internistische Intensivmedizin, Universitätsklinikum des Saarlandes, 66421, Homburg/Saar, Deutschland. christoph.maack@uks.eu. ·Herz · Pubmed #26626553.

ABSTRACT: Acute pulmonary embolism (PE) still represents a challenge regarding a rapid diagnosis and a risk-adapted therapy. In the 2014 guidelines of the European Society of Cardiology (ESC) on the diagnosis and management of acute PE, several new recommendations have been issued based on new study data. Some established scores for risk stratification were developed further and there is now good evidence for the use of age-adjusted D-dimer cut-off levels. For the risk stratification in patients without clinical features of shock, the utilization of the pulmonary embolism severity index (PESI) and simplified PESI (sPESI) scores is recommended. In patients with intermediate risk, right ventricular morphology and function can be evaluated by computer tomography or echocardiography and biomarkers facilitate further risk stratification. For the treatment of patients with venous thromboembolism with or without PE, the non-vitamin K-dependent oral anticoagulants (NOACs) are a safe alternative to the standard anticoagulation regimen with heparin and vitamin K antagonists. Systemic thrombolytic therapy should be restricted to patients with high risk or intermediate high risk with hemodynamic instability. Finally, new recommendations for the diagnosis and therapy of patients with chronic thromboembolic pulmonary hypertension (CTEPH), with cancer or during pregnancy are given.

17 Guideline Part 10: Special Circumstances of Resuscitation: 2015 American Heart Association Guidelines Update for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care. 2015

Lavonas, Eric J / Drennan, Ian R / Gabrielli, Andrea / Heffner, Alan C / Hoyte, Christopher O / Orkin, Aaron M / Sawyer, Kelly N / Donnino, Michael W. · ·Circulation · Pubmed #26472998.

ABSTRACT: -- No abstract --

18 Guideline Evaluation of Patients With Suspected Acute Pulmonary Embolism: Best Practice Advice From the Clinical Guidelines Committee of the American College of Physicians. 2015

Raja, Ali S / Greenberg, Jeffrey O / Qaseem, Amir / Denberg, Thomas D / Fitterman, Nick / Schuur, Jeremiah D / Anonymous420844. · ·Ann Intern Med · Pubmed #26414967.

ABSTRACT: DESCRIPTION: Pulmonary embolism (PE) can be a severe disease and is difficult to diagnose, given its nonspecific signs and symptoms. Because of this, testing patients with suspected acute PE has increased dramatically. However, the overuse of some tests, particularly computed tomography (CT) and plasma d-dimer measurement, may not improve care while potentially leading to patient harm and unnecessary expense. METHODS: The literature search encompassed studies indexed by MEDLINE (1966-2014; English-language only) and included all clinical trials and meta-analyses on diagnostic strategies, decision rules, laboratory tests, and imaging studies for the diagnosis of PE. This document is not based on a formal systematic review, but instead seeks to provide practical advice based on the best available evidence and recent guidelines. The target audience for this paper is all clinicians; the target patient population is all adults, both inpatient and outpatient, suspected of having acute PE. BEST PRACTICE ADVICE 1: Clinicians should use validated clinical prediction rules to estimate pretest probability in patients in whom acute PE is being considered. BEST PRACTICE ADVICE 2: Clinicians should not obtain d-dimer measurements or imaging studies in patients with a low pretest probability of PE and who meet all Pulmonary Embolism Rule-Out Criteria. BEST PRACTICE ADVICE 3: Clinicians should obtain a high-sensitivity d-dimer measurement as the initial diagnostic test in patients who have an intermediate pretest probability of PE or in patients with low pretest probability of PE who do not meet all Pulmonary Embolism Rule-Out Criteria. Clinicians should not use imaging studies as the initial test in patients who have a low or intermediate pretest probability of PE. BEST PRACTICE ADVICE 4: Clinicians should use age-adjusted d-dimer thresholds (age × 10 ng/mL rather than a generic 500 ng/mL) in patients older than 50 years to determine whether imaging is warranted. BEST PRACTICE ADVICE 5: Clinicians should not obtain any imaging studies in patients with a d-dimer level below the age-adjusted cutoff. BEST PRACTICE ADVICE 6: Clinicians should obtain imaging with CT pulmonary angiography (CTPA) in patients with high pretest probability of PE. Clinicians should reserve ventilation-perfusion scans for patients who have a contraindication to CTPA or if CTPA is not available. Clinicians should not obtain a d-dimer measurement in patients with a high pretest probability of PE.

19 Guideline [Management of venous thromboembolism in oncological patients: Spanish clinical practice guidelines. Consensus SEACV-SEOM]. 2015

Olmos, Vanessa Pachón / Ramos Gallo, María José / Rebollo, Maite Antonio / Ortega, Dolores Ballesteros / Docampo, Lara Iglesias / Romera-Villegas, Antonio / Díaz, Enrique Gallardo / Martín, Andrés Muñoz / Anonymous5260823 / Anonymous5270823. ·Servicio de Oncología Médica, Hospital Universitario Ramón y Cajal, Madrid, España. Grupo de Trabajo Cáncer y Trombosis SEOM. Electronic address: li_tor@hotmail.com. · Servicio de Angiología y Cirugía Vascular, Hospital de Cabueñes, Gijón, España. · Servicio de Oncología Médica, Institut Català d'Oncologia/Hospital Duran i Reynals, L'Hospitalet de Llobregat, Barcelona, España. Grupo de Trabajo Cáncer y Trombosis SEOM. · Servicio de Angiología y Cirugía Vascular, Hospital General Universitario de Albacete, Albacete, España. · Servicio de Oncología Médica, Hospital Universitario 12 de Octubre, Madrid, España. Grupo de Trabajo Cáncer y Trombosis SEOM. · Servicio de Angiología y Cirugía Vascular, Hospital Universitari de Bellvitge, L'Hospitalet de Llobregat, Barcelona, España. · Servicio de Oncología Médica, Hospital Universitari Parc Taulí, Sabadell, Barcelona, España. Grupo de Trabajo Cáncer y Trombosis SEOM. · Servicio de Oncología Médica, Hospital General Universitario Gregorio Marañón, Madrid, España. Grupo de Trabajo Cáncer y Trombosis SEOM. ·Med Clin (Barc) · Pubmed #25771086.

ABSTRACT: -- No abstract --

20 Guideline [European Society of Cardiology guidelines on the management of pulmonary embolism]. 2014

Melissopoulou, M / Ancion, A / Lancellotti, P / Anonymous3620824. · ·Rev Med Liege · Pubmed #25796771.

ABSTRACT: In recent years, several studies and new molecules have emerged in the field of pulmonary embolism. Initial patient management requires rapid assessment of clinical condition. In case of shock, a primary reperfusion approach is requi- red (i.e., pharmacological, surgical or percutaneous). In the other cases, the assessment of the risk of early mortality is needed and treatment with anticoagulant should be started. Very low risk patients can be discharged early. High-intermediate risk patients can sometimes benefit from a reperfusion approach. Individual risk stratification can be refined by the assessment of right ventricular function and biomarkers (troponin, B-type natriuretic peptide). The new anticoagulants can be used in this indication. For most patients, the duration of treatment is 3 months. In this article, we summarize the 2014 recommendations of the European Society of Cardiology for the management of pulmonary embolism.

21 Guideline [2014 ESC Guidelines on the diagnosis and management of acute pulmonary embolism]. 2014

Anonymous5680815 / Konstantinides, Stavros / Torbicki, Adam / Agnelli, Giancarlo / Danchin, Nicolas / Fitzmaurice, David / Galiè, Nazzareno / Gibbs, J Simon R / Huisman, Menno / Humbert, Marc / Kucher, Nils / Lang, Irene / Lankeit, Mareike / Lekakis, John / Maack, Christoph / Mayer, Eckhard / Meneveau, Nicolas / Perrier, Arnaud / Pruszczyk, Piotr / Rasmussen, Lars H / Schindler, Thomas H / Svítil, Pavel / Vonk Noordegraaf, Anton / Zamorano, Jose Luis / Zompatori, Maurizio. ·kardiologia_polska@op.pl. ·Kardiol Pol · Pubmed #25524375.

ABSTRACT: -- No abstract --

22 Guideline 2014 ESC guidelines on the diagnosis and management of acute pulmonary embolism. 2014

Konstantinides, Stavros V / Torbicki, Adam / Agnelli, Giancarlo / Danchin, Nicolas / Fitzmaurice, David / Galiè, Nazzareno / Gibbs, J Simon R / Huisman, Menno V / Humbert, Marc / Kucher, Nils / Lang, Irene / Lankeit, Mareike / Lekakis, John / Maack, Christoph / Mayer, Eckhard / Meneveau, Nicolas / Perrier, Arnaud / Pruszczyk, Piotr / Rasmussen, Lars H / Schindler, Thomas H / Svitil, Pavel / Vonk Noordegraaf, Anton / Zamorano, Jose Luis / Zompatori, Maurizio / Anonymous7780804. · ·Eur Heart J · Pubmed #25173341.

ABSTRACT: -- No abstract --

23 Guideline [Chronic thromboembolic pulmonary hypertension--a position paper]. 2014

Wilkens, H / Lang, I / Blankenburg, T / Grohé, C / Guth, S / Held, M / Klepetko, W / Konstantinides, S / Kramm, T / Krüger, U / Lankeit, M / Schäfers, H J / Seyfarth, H J / Mayer, E. ·Klinik für Innere Medizin V, Universitätsklinikum des Saarlandes, Homburg. · Klinik für Innere Medizin II, Abt. Kardiologie, Medizinische Universität Wien. · Krankenhaus Martha-Maria Halle-Dölau, Klinik für Innere Medizin II, Halle. · Klinik für Pneumologie, Evangelische Lungenklinik Berlin Buch. · Abteilung für Thoraxchirurgie, Kerckhoff Klinik, Bad Nauheim. · Missionsärztliche Klinik Würzburg, Abteilung Innere Medizin, Würzburg. · Klinische Abteilung für Thoraxchirurgie, Medizinische Universität Wien. · Centrum für Thrombose und Hämostase (CTH), Universitätsmedizin Mainz. · Klinik für Kardiologie und Angiologie, Herzzentrum Duisburg. · Klinik für Thorax-Herz-Gefäßchirurgie, Universitätsklinikum des Saarlandes, Homburg. · Abteilung Pneumologie (Department für Innere Medizin, Neurologie und Dermatologie), Universitätsklinikum Leipzig. ·Dtsch Med Wochenschr · Pubmed #25084309.

ABSTRACT: -- No abstract --

24 Guideline An official American Thoracic Society/American College of Chest Physicians policy statement: the Choosing Wisely top five list in adult pulmonary medicine. 2014

Wiener, Renda Soylemez / Ouellette, Daniel R / Diamond, Edward / Fan, Vincent S / Maurer, Janet R / Mularski, Richard A / Peters, Jay I / Halpern, Scott D. ·Pulmonary Center, Boston University School of Medicine, Boston, MA; Center for Healthcare Organization & Implementation Research, Edith Nourse Rogers Memorial Veterans Hospital, Bedford, MA; The Dartmouth Institute for Health Policy & Clinical Practice, Hanover, NH. Electronic address: rwiener@bu.edu. · Pulmonary and Critical Care Medicine, Henry Ford Health System, Detroit, MI. · Suburban Lung Associates, Elk Grove Village, IL. · Health Services Research and Development, VA Puget Sound Health Care System, Seattle, WA; Department of Medicine, University of Washington, Seattle, WA. · Department of Medicine, College of Medicine, The University of Arizona, Phoenix, AZ; Quality Improvement and Compliance, National Imaging Associates/Magellan Health Services, Inc, Phoenix, AZ. · The Center for Health Research, Kaiser Permanente Northwest, Portland, OR; Department of Pulmonary/Critical Care Medicine, Northwest Permanente PC, Portland, OR; Department of Medicine, Oregon Health & Science University, Portland, OR. · UT Health Science Center, San Antonio, TX; South Texas Veterans Health Care System, San Antonio, TX. · Departments of Medicine, Biostatistics and Epidemiology, and Medical Ethics and Health Policy, and the Leonard Davis Institute Center for Health Incentives and Behavioral Economics, The University of Pennsylvania, Philadelphia, PA. ·Chest · Pubmed #24889436.

ABSTRACT: The American Board of Internal Medicine Foundation's Choosing Wisely campaign aims to curb health-care costs and improve patient care by soliciting lists from medical societies of the top five tests or treatments in their specialty that are used too frequently and inappropriately. The American Thoracic Society (ATS) and American College of Chest Physicians created a joint task force, which produced a top five list for adult pulmonary medicine. Our top five recommendations, which were approved by the executive committees of the ATS and American College of Chest Physicians and published by Choosing Wisely in October 2013, are as follows: (1) Do not perform CT scan surveillance for evaluation of indeterminate pulmonary nodules at more frequent intervals or for a longer period of time than recommended by established guidelines; (2) do not routinely offer pharmacologic treatment with advanced vasoactive agents approved only for the management of pulmonary arterial hypertension to patients with pulmonary hypertension resulting from left heart disease or hypoxemic lung diseases (groups II or III pulmonary hypertension); (3) for patients recently discharged on supplemental home oxygen following hospitalization for an acute illness, do not renew the prescription without assessing the patient for ongoing hypoxemia; (4) do not perform chest CT angiography to evaluate for possible pulmonary embolism in patients with a low clinical probability and negative results of a highly sensitive D-dimer assay; (5) do not perform CT scan screening for lung cancer among patients at low risk for lung cancer. We hope pulmonologists will use these recommendations to stimulate frank discussions with patients about when these tests and treatments are indicated--and when they are not.

25 Guideline National Consensus on the Diagnosis, Risk Stratification and Treatment of Patients with Pulmonary Embolism. Spanish Society of Pneumology and Thoracic Surgery (SEPAR). Society Española Internal Medicine (SEMI). Spanish Society of Thrombosis and Haemostasis (SETH). Spanish Society of Cardiology (ESC). Spanish Society of Medicine Accident and Emergency (SEMES). Spanish Society of Angiology and Surgery Vascular (SEACV). 2013

Uresandi, Fernando / Monreal, Manuel / García-Bragado, Ferrán / Domenech, Pere / Lecumberri, Ramón / Escribano, Pilar / Zamorano, José Luis / Jiménez, Sonia / Ruiz-Artacho, Pedro / Lozano, Francisco / Romera, Antonio / Jiménez, David / Anonymous5300769 / Bellmunt, Sergi / Cuenca, Jorge / Fernández, Álvaro / Fernández, Fidel / Ibáñez, Vicente / Lozano, Francisco / March, José Ramón / Romera, Antonio / Almenar, Luis / Castro, Antonio / Escribano, Pilar / Lázaro, María / Luis Zamorano, José / Alonso, José Ramón / Ramón Casal, José / Miguel Franco, José / Jiménez, Sonia / Merlo, Marta / Perales, Ramón / Piñera, Pascual / Ruiz-Artacho, Pedro / Suero, Coral / Barba, Raquel / Fernández-Capitán, Carmen / García-Bragado, Ferrán / Gómez, Vicente / Monreal, Manuel / Nieto, José Antonio / Riera-Mestre, Antoni / Suárez, Carmen / Trujillo-Santos, Javier / Conget, Francisco / Jara, Luis / Jiménez, David / Lobo, José Luis / de Miguel, Javier / Nauffal, Dolores / Oribe, Mikel / Otero, Remedios / Uresandi, Fernando / Domenech, Pere / González-Porras, José Ramón / Lecumberri, Ramón / Llamas, Pilar / Mingot, Eva / Pina, Elena / Rodríguez-Martorell, Javier / Anonymous5310769 / Anonymous5320769 / Anonymous5330769 / Anonymous5340769 / Anonymous5350769 / Anonymous5360769. ·Servicio de Neumología, Hospital de Cruces, Bilbao, España. ·Arch Bronconeumol · Pubmed #24041726.

ABSTRACT: -- No abstract --

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