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Spinal Diseases: HELP
Articles by Carole Desthieux
Based on 2 articles published since 2009
(Why 2 articles?)
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Between 2009 and 2019, Carole Desthieux wrote the following 2 articles about Spinal Diseases.
 
+ Citations + Abstracts
1 Article Determinants of Patient-Physician Discordance in Global Assessment in Psoriatic Arthritis: A Multicenter European Study. 2017

Desthieux, Carole / Granger, Benjamin / Balanescu, Andra Rodica / Balint, Peter / Braun, Jürgen / Canete, Juan D / Heiberg, Turid / Helliwell, Philip S / Kalyoncu, Umut / Kvien, Tore K / Kiltz, Uta / Niedermayer, Dora / Otsa, Kati / Scrivo, Rossana / Smolen, Josef / Stamm, Tanja A / Veale, Douglas J / de Vlam, Kurt / de Wit, Maarten / Gossec, Laure. ·Sorbonne Universités, UPMC University Paris 06, Institut Pierre Louis d'Epidémiologie et de Santé Publique, GRC-UPMC 08 (EEMOIS), AP-HP, Hôpital Pitié Salpêtrière, Paris, France. · University of Medicine and Pharmacy Carol Davila and St Maria Hospital, Bucharest, Romania. · National Institute of Rheumatology and Physiotherapy, Budapest, Hungary. · Ruhrgebiet, Herne and Ruhr-Universität Bochum, Herne, Germany. · Hospital Clínic and IDIBAPS, Barcelona, Spain. · Østfold University College, Halden, and Regional Research Support, Oslo University Hospital, Oslo, Norway. · University of Leeds, Leeds, UK. · Hacettepe University, Ankara, Turkey. · Diakonhjemmet Hospital, Oslo, Norway. · Tallinn Central Hospital, Tallinn, Estonia. · Sapienza Università di Roma, Rome, Italy. · III Medical University of Vienna, Vienna, Austria. · Dublin Academic Medical Centre and St Vincent's University Hospital, Dublin, Ireland. · University Hospitals Leuven, Leuven, Belgium. · Patient Research Partner, People with Arthritis/Rheumatism in Europe, Zurich, Switzerland. ·Arthritis Care Res (Hoboken) · Pubmed #27998026.

ABSTRACT: OBJECTIVE: Patient-physician discordance in global assessment of disease activity concerns one-third of patients, but what does it reflect? We aimed to assess patient-physician discordance in psoriatic arthritis (PsA) and patient-reported domains of health (physical and psychological) associated with discordance. METHODS: We analyzed the PsAID (Psoriatic Arthritis Impact of Disease), a cross-sectional, multicenter European study of patients with PsA according to expert opinion. Patient global assessment (PGA) and physician global assessment (PhGA) were rated on a 0-10 numeric rating scale. Discordance was defined as the difference (PGA-PhGA) and as the absolute difference |PGA-PhGA| ≥3 points. Determinants of PGA-PhGA were assessed by a stepwise multivariate linear regression among 12 physical and psychological aspects of impact: pain, skin problems, fatigue, ability to work/leisure, functional incapacity, feeling of discomfort, sleep disturbance, anxiety/fear, coping, embarrassment/shame, social participation, and depressive affects. RESULTS: In 460 patients (mean ± SD age 50.6 ± 12.9 years, 52.2% female, mean ± SD disease duration 9.5 ± 9.5 years, mean ± SD Disease Activity Index for Psoriatic Arthritis score 30.8 ± 32.4, and 40.4% undergoing treatment with biologic agents), the mean ± SD PGA was higher than the mean PhGA, with a mean absolute difference of 1.9 ± 1.8 points. Discordance defined by |PGA-PhGA| ≥3 of 10 concerned 134 patients (29.1%), and 115 patients (85.8% of the patients with discordance) had PGA>PhGA. Higher fatigue (β = 0.14), lower self-perceived coping (β = 0.23), and impaired social participation (β = 0.16) were independently associated with a higher difference (PGA-PhGA). CONCLUSION: Discordance concerned 29.1% of these patient/physician dyads, mainly by PGA>PhGA. Factors associated with discordance were psychological rather than physical domains of health. Discordance was more frequent in patients in remission, indicating more work is needed on the patient perspective regarding disease activity.

2 Article Patient-physician discordance in global assessment in early spondyloarthritis and its change over time: the DESIR cohort. 2016

Desthieux, Carole / Molto, Anna / Granger, Benjamin / Saraux, Alain / Fautrel, Bruno / Gossec, Laure. ·Department of Rheumatology, Sorbonne Universités, UPMC Univ Paris 06, Institut Pierre Louis d'Epidémiologie et de Santé Publique, GRC-UPMC 08 (EEMOIS); AP-HP, Pitié Salpêtrière Hospital, Paris, France. · Department of Rheumatology, Paris Descartes University, Cochin Hospital, Paris, France. · Department of Biostatistics, Sorbonne Universités, UPMC Univ Paris 06, Institut Pierre Louis d'Epidémiologie et de Santé Publique, GRC-UPMC 08 (EEMOIS); AP-HP, Pitié Salpêtrière Hospital, Paris, France. · Department of Rheumatology, CHU Brest, La Cavale Blanche Hospital, Brest, France. ·Ann Rheum Dis · Pubmed #26493818.

ABSTRACT: OBJECTIVE: To assess patient-physician discordance in global assessment of disease activity in early axial spondyloarthritis (axSpA) over time and determinants of discordance. METHODS: DESIR (Devenir des Spondyloarthropathies Indifférenciées Récentes) is a French, multicentre, longitudinal cohort of patients with early inflammatory back pain suggestive of axSpA. Patient global assessment (PGA) and physician global assessment (PhGA) were rated with a 0-10 numerical rating scale, every 6 months during 2 years then at 3 years. Discordance was defined by the absolute difference |PGA-PhGA|≥3 (range 0-10) and was analysed at each visit. Determinants of (PGA-PhGA) were assessed at the visit level by a generalised linear mixed model. RESULTS: A total of 702 patients were analysed at baseline (401 with complete data over 3 years): mean age 33.8±8.6 years, 379 (54.0%) female, mean symptom duration 18.1±10.5 months. Mean PGA values were always higher than mean PhGA values with a mean absolute difference of 1.8 points. At baseline, 202 (28.8%) patients had discordance mainly by PGA>PhGA; over 3 years the frequency of discordance was stable (range 25.5-28.8%). Discordance was not stable at the patient level, 118 (29.4%) patients were discordant once and 88 (22.0%) twice, and only 92 (22.9%) more than twice. Determinants of (PGA-PhGA) were spine pain (β=0.24, p<0.001) and fatigue (β=0.13, p<0.001). CONCLUSIONS: Discordance concerned a quarter of patients with early axSpA. Over 3 years of follow-up, discordance did not decrease (no 'reference shift'). Discordance was not a stable trait, indicating discordance is not a patient characteristic.